Photocatalytic Radical Cascade Cyclization of N-(o-Cyanobiaryl)acrylamides with Sulfonyl Chlorides DOI
Min Gao, Jian-Hong Fan, Yu Liu

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 2, 2025

A photoredox-catalyzed radical cascade cyclization of N-(o-cyanobiaryl)acrylamides with sulfonyl chlorides for the construction sulfonyl-containing pyrido[4,3,2-gh]phenanthridines has been disclosed. The developed synthetic tool tolerates a broad range to undergo sequence, including addition, nitrile insertion, and cyclization.

Язык: Английский

Stereospecific Assembly of Trisubstituted Alkenes via Photoinduced Nitrogen‐Centered Radical‐Triggered C—C Bond Cleavage/Functionalization of Oxime Esters DOI

Yu Bao,

Zhi‐Jie Song,

Jin‐Long Dai

и другие.

Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(12), С. 1399 - 1406

Опубликована: Фев. 29, 2024

Comprehensive Summary A general and convenient photoredox‐catalyzed acylation alkylcyanation of MBH acetates has been established, enabling the assembly C(sp 2 )–C(sp 3 ) bond by a nitrogen‐centered radical strategy for synthesis trisubstituted alkenes in moderate to excellent chemical yields (48 examples total). The reaction with acyl (indanone) oxime esters afforded containing 1,4‐dicarbonyl groups. Interestingly, use Eosin Y as photocatalyst catalytic system resulted formation distal cyano group‐anchored via deconstructive functionalization cycloketone esters. Notably, these resulting compounds could be applied late‐stage transformations, providing important methods dihydropyridazin‐3(2 H )‐one.

Язык: Английский

Процитировано

9
Photoredox catalytic alkylarylation of alkynes with arylsulfonylacetate as bifunctional reagent DOI

Chonglong He,

Min Wang, Yulong Wang

и другие.

Science China Chemistry, Год журнала: 2024, Номер 67(6), С. 2022 - 2028

Опубликована: Март 7, 2024

Язык: Английский

Процитировано

9
A radical Smiles rearrangement difunctionalization of activated alkenes via desulfonylation and insertion of sulfur dioxide relay strategy DOI

Si‐Wei Tian,

Zhentao Luo,

Biquan Xiong

и другие.

Green Chemistry, Год журнала: 2024, Номер 26(11), С. 6774 - 6778

Опубликована: Янв. 1, 2024

A novel and attractive photochemical difunctionalization of N -tosyl acrylamide for constructing alkylsulfonylated oxindoles amides with excellent substrate adaptability via a radical Smiles rearrangement strategy is described.

Язык: Английский

Процитировано

8
Photo‐/Electrocatalytic Difunctionalization of Alkenes Enabled by C‐H Radical Functionalization DOI

Zilong Zhou,

Yin Zhang,

Peizhe Cui

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 30(62)

Опубликована: Авг. 10, 2024

The difunctionalization of alkenes represents a powerful tool to incorporate two functional groups into the alkene bones for increasing molecular complexity and has been widely utilizations in chemical synthesis. Upon catalysis green, sustainable, mild photo-/electrochemistry technologies, much attentions have attracted development new tactics transformations important alkane feedstocks driven by C-H radical functionalization. Herein, we summarize recent advances photo-/electrocatalytic enabled We detailedly discuss substrate scope mechanisms reactions selecting impressive synthetic examples, which are divided four sections based on final terminated step, including oxidative radical-polar crossover coupling, reductive radical-radical transition-metal-catalyzed coupling.

Язык: Английский

Процитировано

8
Photocatalytic Radical Cascade Cyclization of N-(o-Cyanobiaryl)acrylamides with Sulfonyl Chlorides DOI
Min Gao, Jian-Hong Fan, Yu Liu

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 2, 2025

A photoredox-catalyzed radical cascade cyclization of N-(o-cyanobiaryl)acrylamides with sulfonyl chlorides for the construction sulfonyl-containing pyrido[4,3,2-gh]phenanthridines has been disclosed. The developed synthetic tool tolerates a broad range to undergo sequence, including addition, nitrile insertion, and cyclization.

Язык: Английский

Процитировано

1