Synthesis of 4‐Cyclobutene‐Isoquinolines From Aryl Imidates by Ru(II)‐Catalyzed Domino C–H Activation/Cyclization DOI

Min Wang,

Lei Gao, Maozhong Miao

и другие.

Applied Organometallic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 13, 2024

ABSTRACT A highly regioselective approach for constructing 4‐cyclobutene‐isoquinoline derivatives through ruthenium‐catalyzed domino C–H activation/cyclization of aryl imidates has been demonstrated. This new transformation tolerates various substituted functional groups on and propargylic monofluoroalkynes, resulting in the corresponding products being delivered moderate yields.

Язык: Английский

Synthesis of Alkynylsilanes: A Review of the State of the Art DOI
Krzysztof Kuciński

Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(11), С. 2382 - 2431

Опубликована: Апрель 12, 2024

Abstract This contribution offers a comprehensive overview of methods for forging sp C−Si bonds. Over time, alkynylsilanes (silylacetylenes), once considered mere byproducts hydrosilylation processes, have become essential building blocks in organic synthesis. literature review traces the evolution their synthesis, from traditional methodologies relying on organolithium and organomagnesium compounds to more advanced cross‐coupling reactions involving hydro‐ carbosilanes. Focused primarily past 25 years (2000–2024), it also extensively references significant historical breakthroughs. By analyzing synthetic methodologies, not only survey current state knowledge but identifies areas improvement. Furthermore, emphasize importance 1‐alkynylsilanes (1‐silyl‐1‐alkynes), selected applications these are highlighted, confirming potential

Язык: Английский

Процитировано

6
Co(III)-Catalyzed Regioselective Benzannulation of Substituted Pyridones with 1,6-Diynes via Dual C-H Bond Activation DOI
Suresh Kumar Yadav, Masilamani Jeganmohan

Chemical Communications, Год журнала: 2024, Номер 60(63), С. 8296 - 8299

Опубликована: Янв. 1, 2024

A Co(III)-catalyzed site-selective C5 and C6 benzannulation of substituted pyridones with 1,6-diynes

Язык: Английский

Процитировано

4
Palladium-Catalyzed Oxidative Cycloaddition of 1-Indanones and Internal Aryl Alkynes toward Benzo[c]fluorenone Derivatives DOI
Xu Zhang,

Tongtong Ni,

Mengfan Chang

и другие.

Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

An efficient palladium-catalyzed dehydrogenative [4+2] annulation of 1-indanones with alkynes results in the generation diverse benzo[ c ]fluorenone derivatives satisfactory yields and regioselectivity.

Язык: Английский

Процитировано

0
Synthesis of Sulfonimidamide‐Based 1,2‐Benzothiazines by [4+2] Oxidative Annulation of Sulfonimidamides and Alkynes in Water under Visible Light DOI

N. Karthikeyan,

S. Ravindra,

V. R. Padma Priya

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(6)

Опубликована: Янв. 5, 2024

Abstract Herein, we disclose a visible‐light‐induced rhodium‐catalyzed oxidative C−H/N−H bond activation of sulfonimidamides (SIAs) and subsequent [4+2] annulation with an alkyne in water to yield SIA‐based 1,2‐benzothiazines good high yields short reaction times. Further, the C=C benzothiazine can be cleaved under environmentally friendly conditions (oxygen atmosphere blue LEDs) deliver o ‐acyl‐ N ‐acyl SIAs. Interestingly, SIAs also synthesized directly from very without isolating benzothiazine. The selective efficient reduction presence InCl 3 /R SiH led formation hitherto unknown dihydro‐1,2‐benzothiazine quantitative yield.

Язык: Английский

Процитировано

2
Ru(II)-Catalyzed Divergent C–H Alkynylation Cascade with Bifunctional α-Alcohol Haloalkynes DOI

Qiaoya Zhang,

Yinling Li,

Yabo Chen

и другие.

Organic Letters, Год журнала: 2024, Номер 26(11), С. 2186 - 2191

Опубликована: Март 7, 2024

Native functionality directed the C–H activation cascade to enable rapid construction of molecular complexity, featuring step-economy and synthetic efficiency. Herein, by exploiting bifunctional α-alcohol haloalkynes, we developed Ru(II)-catalyzed carboxylic acid, amine, amide assisted divergent alkynylation annulation cascade, affording polyfunctional heterocycles. Significantly, a bilateral aryl polycyclization azobenzenes was achieved using versatile haloalkynes.

Язык: Английский

Процитировано

2
Chemoselective Preparation of Alkynes from Vicinal and Geminal Dibromoalkenes DOI
Hisashi Okumura, Nurcahyo Iman Prakoso,

Tatsuya Morozumi

и другие.

Organic Letters, Год журнала: 2024, Номер 26(46), С. 9817 - 9821

Опубликована: Ноя. 9, 2024

The reductive conversion of vicinal and geminal dibromoalkenes into the corresponding alkynes with

Язык: Английский

Процитировано

1
Theoretical Study on the Mechanism of Ru(II)-Catalyzed Intermolecular [3 + 2] Annulation between o-Toluic Acid and 3,5-Bis(trifluoromethyl)benzaldehyde: Octahedral vs Trigonal Bipyramidal DOI
Dan-Yang Liu, De‐Cai Fang

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Сен. 23, 2024

Density functional theory was utilized to investigate the mechanism of Ru(II)-catalyzed aromatic C-H activation and addition aldehydes. The proposed catalytic cycle consists bond activation, aldehyde carbonyl insertion for C-C coupling, lactonization formation final product, product separation, catalyst recovery. Our calculations suggest that Ru(OAc)

Язык: Английский

Процитировано

0
Synthesis of 4‐Cyclobutene‐Isoquinolines From Aryl Imidates by Ru(II)‐Catalyzed Domino C–H Activation/Cyclization DOI

Min Wang,

Lei Gao, Maozhong Miao

и другие.

Applied Organometallic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 13, 2024

ABSTRACT A highly regioselective approach for constructing 4‐cyclobutene‐isoquinoline derivatives through ruthenium‐catalyzed domino C–H activation/cyclization of aryl imidates has been demonstrated. This new transformation tolerates various substituted functional groups on and propargylic monofluoroalkynes, resulting in the corresponding products being delivered moderate yields.

Язык: Английский

Процитировано

0