Halonium and Chalconium Salt-Catalyzed Schiff Condensation: Kinetics and DFT Insights into Organocatalyst Activity Parameters

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Chalconium and halonium salts catalyze Schiff condensation. Kinetic data DFT calculations show that the catalytic activity correlates with maximum electrostatic potential on σ-holes, whereas other factors are less significant.

Язык: Английский

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Unexpected Inhibition of the Knoevenagel Condensation in Methanol by Iodonium Salt Served as Electrophilic Activator

Journal of Physical Organic Chemistry, Год журнала: 2025, Номер 38(3)

Опубликована: Фев. 14, 2025

ABSTRACT Halogen bond donors are recognized as electrophilic catalysts in reactions involving carbonyl compounds. This study describes an unexpected inhibition of the Knoevenagel condensation by catalyst. To elucidate intricacies mechanism, overall reaction order and rate constants were determined using 1 H NMR spectroscopy, further experiments with different nucleophiles conducted. The findings revealed that primary is attributed to a substantial acceleration side aldehyde methanolysis, which hinders formation final alkene product.

Язык: Английский

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Re-Evaluating Chalcogen Bonding Trends: Catalytic Performance of Chaclonium(IV) Salts in the Povarov [4+2] Cycloaddition Reaction

Russian Journal of General Chemistry, Год журнала: 2024, Номер 94(11), С. 2910 - 2914

Опубликована: Ноя. 1, 2024

Язык: Английский

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Comparative Study of the Catalytic Activity of Hypervalent Halogen(III) and Chalcogen(IV) Salts in the Imine–Isocyanide Coupling

Russian Journal of General Chemistry, Год журнала: 2024, Номер 94(10), С. 2632 - 2637

Опубликована: Окт. 1, 2024

Язык: Английский

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