Synthesis of 5‐Arylselenyluracils via Bromide‐Catalyzed Selective C(sp2)‐H Selenylation of Uracils
Asian Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 28, 2025
Abstract
Herein,
an
efficient
method
for
the
synthesis
of
5‐arylselenyluracils
via
bromide‐catalyzed
selective
C(
sp
2
)‐H
selenylation
uracils
using
boronic
acid
and
elemental
selenium
as
selenyl
source
was
successfully
developed.
This
proceeded
smoothly
a
series
arylboronic
acids
under
metal‐free
strong
oxidant‐free
conditions.
protocol
offered
simple
catalytic
conditions,
high
efficiency,
good
functional
group
compatibility,
easy
operation,
scalable.
Furthermore,
mechanistic
studies
suggested
that
this
transformation
possibly
undergone
radical
pathway.
Язык: Английский
Electrochemical Synthesis of 4‐Selenylated Oxazolones via Oxyselenylation of Ynamides
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 19, 2024
Abstract
Electrosynthesis
of
selenylated‐oxazolone
derivatives
via
cascade
selenylation/cyclization
ynamides
was
disclosed.
A
series
diaryl
diselenides,
dialkyl
and
heteroaryl‐substituted
tolerated
in
this
protocol
delivered
4‐selenyloxazolones
28–83%
yields.
The
scale‐up
reaction
the
oxidation
performed
to
showcase
practicability
method.
Furthermore,
mechanistic
experiments
indicated
that
a
cationic
pathway
instead
radical
probably
involved.
Язык: Английский