Multicomponent Electrosynthesis of Enaminyl Sulfonates Starting from Alkylamines, SO2, and Alcohols DOI Creative Commons

Florian A. Breitschaft,

Alicia L. Saak,

Christian Krumbiegel

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

An electrochemical one-pot synthesis of enaminyl sulfonate esters was established, featuring a quasidivided cell under constant current conditions. The multicomponent reaction utilizes simple and readily available alkylamines an easy-to-use stock solution SO2 alcohols. Omission additional supporting electrolyte through in-situ-generated monoalkylsulfite facilitates the downstream processing. A diverse scope with more than 28 examples yields up to 85% as well 20-fold scale-up prove feasibility this novel protocol.

Язык: Английский

Trends and Challenges in Electrifying Technical Organic Synthesis DOI Creative Commons
Philipp Röse,

Paul Neugebauer,

Siddharth Tamang

и другие.

Chemie Ingenieur Technik, Год журнала: 2025, Номер unknown

Опубликована: Март 18, 2025

Abstract Organic electrosynthesis is a potential enabler for the energy and resource transition in chemical industry as it offers sustainable alternative to homogeneous or heterogeneous processes producing fine commodity chemicals. It utilizes electricity instead of hazardous reagents and, thus, also allows reducing product's carbon footprint waste production. enables dynamic operation safe due galvanostatic process control. Electro‐organic are not yet widespread. Engineering tools have been tailored electro‐organic processes, more quantitative model‐based insight needed. Extensive adoption requires efforts regarding electrode material performance stability, scalable reactor design, digitization. Addressing these issues interdisciplinary collaboration, particularly between chemists engineers, accelerate implementation with high efficiency economic feasibility.

Язык: Английский

Процитировано

1

Multicomponent Electrosynthesis of Enaminyl Sulfonates Starting from Alkylamines, SO2, and Alcohols DOI Creative Commons

Florian A. Breitschaft,

Alicia L. Saak,

Christian Krumbiegel

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

An electrochemical one-pot synthesis of enaminyl sulfonate esters was established, featuring a quasidivided cell under constant current conditions. The multicomponent reaction utilizes simple and readily available alkylamines an easy-to-use stock solution SO2 alcohols. Omission additional supporting electrolyte through in-situ-generated monoalkylsulfite facilitates the downstream processing. A diverse scope with more than 28 examples yields up to 85% as well 20-fold scale-up prove feasibility this novel protocol.

Язык: Английский

Процитировано

0