Beilstein Journal of Organic Chemistry, Год журнала: 2025, Номер 21, С. 630 - 638

Опубликована: Март 19, 2025

The electrochemical synthesis of 2-aminoprolines based on anodic decarboxylation–intramolecular amidation readily available N -acetylamino malonic acid monoesters is reported. decarboxylative under Hofer–Moest reaction conditions proceeds in an undivided cell constant current aqueous acetonitrile and provides access to -sulfonyl, -benzoyl, -Boc-protected 2-aminoproline derivatives.

Язык: Английский