Organic Letters, Год журнала: 2023, Номер 25(51), С. 9142 - 9146
Опубликована: Дек. 19, 2023
This paper describes a B(C6F5)3-catalyzed hydrogenation of β-substituted α,β-unsaturated imines by using as low 0.2 mol % catalyst. A variety tetrasubstituted enamines were afforded in 95-99% yields. It provides an efficient and facile way without the need for column chromatography purification.
Язык: Английский
Chemical Reviews, Год журнала: 2022, Номер 122(18), С. 14346 - 14404
Опубликована: Авг. 16, 2022
Asymmetric catalysis has emerged as a general and powerful approach for constructing chiral compounds in an enantioselective manner. Hence, developing novel ligands catalysts that can effectively induce asymmetry reactions is crucial modern chemical synthesis. Among such catalysts, dienes their metal complexes have received increased attention, great progress been made over the past two decades. This review provides comprehensive critical information on essential aspects of diene importance asymmetric catalysis. The literature covered ranges from August 2003 (when first effective ligand was reported) to October 2021. divided into parts. In part, are categorized according structures, preparation methods summarized. second applications transformations presented reaction types.
Язык: Английский
Процитировано
101
Chemical Society Reviews, Год журнала: 2023, Номер 52(24), С. 8580 - 8598
Опубликована: Янв. 1, 2023
This review provides an overview of the important progress in FLP-catalyzed asymmetric reactions made over past 15 years, and both merits limitations FLP-catalysis have been highlighted.
Язык: Английский
Процитировано
20
The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(5), С. 3335 - 3339
Опубликована: Фев. 17, 2023
A chiral phosphoric acid catalyzed asymmetric transfer hydrogenation of quinolines with regenerable dihydrophenanthridine derived by a borane-catalyzed phenanthridine under H2 has been successfully realized. Despite the competition racemic pathway, variety tetrahydroquinolines were furnished in high yields up to 91% ee.
Язык: Английский
Процитировано
13
Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Фев. 26, 2025
This paper describes an asymmetric hydrogenation of 1,3-disubstituted isoquinolines catalyzed by chiral borane derived from alkene, giving the desired cis-products in high yields with up to 96% ee. In particular, challenging 1,3,4-trisubstituted could proceed smoothly afford corresponding products moderate ee's for first time.
Язык: Английский
Процитировано
0
The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Апрель 8, 2025
An enantioselective synthesis of 2-aryl 3,3-disubstituted 3H-indoles has been successfully developed via a deracemization process involving borane-catalyzed hydrogenation and chiral phosphoric-acid-catalyzed asymmetric transfer hydrogenation. A variety were effective substrates to afford the desired indolines in 86-95% yields with 45-92% ee's.
Язык: Английский
Процитировано
0
The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(5), С. 3666 - 3671
Опубликована: Фев. 15, 2024
The asymmetric hydrogenation of quinoxalines represents one the most efficient approaches for synthesis optically active tetrahyroquinoxalines. In this paper, we demonstrate a metal-free transfer 2-substituted with regenerable dihydrophenanthridine under H2 using combination chiral phosphoric acid and achiral borane as catalysts. A wide range tetrahydroquinoxalines were produced in high yields ≤98% ee.
Язык: Английский
Процитировано
2
Chem Catalysis, Год журнала: 2022, Номер 2(11), С. 2865 - 2875
Опубликована: Сен. 29, 2022
Язык: Английский
Процитировано
10
Angewandte Chemie International Edition, Год журнала: 2023, Номер 63(5)
Опубликована: Дек. 9, 2023
The asymmetric reduction of 1,2-diketones for the synthesis optically active 1,2-diols, especially 1,2-anti-diols, remains a formidable challenge. In this paper, we describe first highly stereoselective hydrosilylation unsymmetrical vicinal diketones with PhSiH
Язык: Английский
Процитировано
3
Chinese Journal of Chemistry, Год журнала: 2023, Номер 42(6), С. 631 - 635
Опубликована: Ноя. 21, 2023
Comprehensive Summary The asymmetric hydrogenation of N ‐heteroarenes provides an efficient method for the synthesis optically active cyclic secondary amines. In this paper, we described phenanthridines using a chiral mono‐alkene‐derived borane. A variety dihydrophenanthridines were furnished in high yields with up to 93% ee. current catalytic system was very sensitive steric hindrance phenanthridines. Bulky substituents at one phenyl group required obtain enantioselectivity. But large on carbon C=N bonds would diminish reactivity sharply.
Язык: Английский
Процитировано
2
Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(10), С. 3558 - 3558
Опубликована: Янв. 1, 2023
Organosilicon products have become an indispensable part of our lives today.Catalytic hydrosilylation reaction is one the important methods for preparing organosilicon chemicals and materials.The research development inexpensive excellent catalysts received extensive attention.At present, on catalytic mainly focuses exploring properties new noble metal non-precious complexes.However, due to high cost metals low activity non-noble complexes, photocatalysis environmentally friendly safe method.Catalytic photocatalytic reactions much attention.In this paper, progress in recent years introduced.
Язык: Английский
Процитировано
1