Electrochemical stereoselective synthesis of polysubstituted 1,4-dicarbonyl Z-alkenes via three-component coupling of sulfoxonium ylides and alkynes with water
Haoran Li,
Y. Ran,
Yu-Yi Zhu
и другие.
Chemical Science,
Год журнала:
2024,
Номер
15(21), С. 8156 - 8162
Опубликована: Янв. 1, 2024
The
first
straightforward
strategy
for
the
synthesis
of
1,4-dicarbonyl
Z-alkenes
has
been
developed
via
an
electrochemical
cross-coupling
reaction
sulfoxonium
ylides
and
alkynes
with
water.
metal-free
protocol
showed
easy-to-handle
nature,
good
functional
group
tolerance,
high
Z-stereoselectivity,
which
is
rare
in
previous
cases.
proposed
mechanism
was
convincingly
established
by
carrying
out
a
series
control
experiments,
cyclic
voltammetry
density
theory
(DFT)
studies.
Язык: Английский
An electrochemical method for direct sulfonylation of BODIPYs under green conditions
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
11(2), С. 477 - 483
Опубликована: Дек. 1, 2023
An
environmentally
benign
electrochemical
approach
has
been
developed
for
the
construction
of
β-sulfonylated
BODIPYs
by
using
sulfonylhydrazide
as
sulfonyl
source.
Язык: Английский
Highly Selective Hydrolysis of Amides via Electroreduction
Green Chemistry,
Год журнала:
2024,
Номер
26(14), С. 8204 - 8210
Опубликована: Янв. 1, 2024
Deprotection
of
amides
is
a
virtually
universal
transformation
in
organic
synthesis,
often
employing
traditional
active
reductants.
Herein,
we
describe
sustainable
electrocatalytic
hydrolysis
utilizing
water
as
the
hydrogen
source.
Язык: Английский
Electrochemical Cascade Annulation for the Synthesis of 3‐Sulfanylquinoline Derivatives Under Mild Conditions
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
42(16), С. 1833 - 1838
Опубликована: Апрель 17, 2024
Comprehensive
Summary
An
efficient
electrochemical
approach
has
been
developed
for
the
construction
of
3‐sulfanylquinoline
derivatives
by
treating
phenylethynylbenzoxazinanones
with
disulfides
in
an
undivided
cell.
The
protocol
provided
a
convenient
route
to
functionalized
quinolines
good
functional
group
tolerance.
Moreover,
it
does
not
require
any
metal
catalysts
or
additives,
furnishing
series
biological
moderate
yields.
Язык: Английский
Electrochemical dehydrogenative phosphorothiolation of heteroarenes
Tetrahedron,
Год журнала:
2024,
Номер
163, С. 134131 - 134131
Опубликована: Авг. 1, 2024
Язык: Английский
Electrochemically Driven α,β-Dehydrogenation of Flavanones, Azaflavanones, and Thioflavanones
Organic Letters,
Год журнала:
2024,
Номер
26(44), С. 9547 - 9552
Опубликована: Окт. 25, 2024
α,β-Dehydrogenation
of
flavanones
represents
an
ideal
strategy
to
synthesize
various
flavones
but
remains
challenging
because
the
requirements
for
rigorous
conditions.
Herein,
a
straightforward
and
efficient
route
synthesis
via
electrocatalysis
is
disclosed.
This
electro-oxidative
approach
shows
broad
substrate
scope,
including
azaflavanones
thioflavanones,
which
could
be
performed
in
undivided
cell
without
removal
air
or
water
absence
metal
catalysts,
ligands,
external
oxidants.
Moreover,
combination
cyclic
voltammetry,
square
wave
voltammetry
experiments,
density
functional
theory
(DFT)
calculations
revealed
plausible
mechanism.
Язык: Английский
Regioselectively electrochemical Csp3-H alkoxylation for functionalized indanone
Green Synthesis and Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 1, 2024
Язык: Английский
Non-classical effective methods for reduction of heteroaromatic compounds
Russian Chemical Reviews,
Год журнала:
2024,
Номер
93(11), С. RCR5149 - RCR5149
Опубликована: Окт. 30, 2024
The
review
summarizes
the
known
data
on
various
methods
for
saturation
and
dearomatization
of
heterocyclic
moieties,
forming
diverse
aromatic
compounds.
Since
classical
hydrogenation
substrates
with
molecular
hydrogen
has
a
number
fundamental
drawbacks
that
hinder
both
its
use
at
laboratory
level
widespread
implementation
in
industrial
production,
main
attention
is
paid
to
non-classical
described
literature
over
last
20–25years.
ammonia-free
Birch
reduction,
transfer
hydrogenation,
reduction
by
Hantzsch
esters
some
other
reactions
involving
compounds
are
summarized
systematized.
It
shown
such
or
heterocycles
can
cases
be
more
efficient
than
procedures.<br>
bibliography
includes
173
references.
Язык: Английский
Electrochemical Reductive Bimolecular Cycloaddition of 2-Arylideneindane-1,3-diones for the Synthesis of Spirocyclopentanole Indane-1,3-diones
Luchao Li,
Binyan Xu,
Chenglong Jia
и другие.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 25, 2024
An
electrochemical
reductive
bimolecular
cycloaddition
of
2-arylideneindane-1,3-diones
has
been
reported
for
the
synthesis
spirocyclopentanole
indane-1,3-diones
bearing
five
contiguous
stereocenters
with
vicinal
tetrasubstituted
stereocenters,
especially
involving
a
quaternary
carbon
center,
in
moderate
to
good
yields
and
excellent
diastereoselectivities.
The
present
protocol
features
mild
reaction
conditions,
no
external
chemical
redox
reagents,
atom
economy,
gram-scale
synthesis.
In
addition,
mechanistic
investigation
indicates
that
reactions
proceed
through
radical
pathway.
Язык: Английский