Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles DOI
Peng‐Fei Huang,

Jia-Le Fu,

Ying Peng

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(18), С. 3752 - 3760

Опубликована: Янв. 1, 2024

2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur as source. Both aliphatic amines aryl demonstrate good compatibility at room temperature, highlighting broad group tolerance this approach. Additionally, selenium demonstrated reactivities comparable to those sulfur.

Язык: Английский

Magnetic Hollowed CoFe Alloy@C Prism Catalyst for N-Alkylation of Alcohols and Amines DOI
Xin Zhuo,

Jianyao Kou,

Chun Li

и другие.

Inorganic Chemistry, Год журнала: 2025, Номер 64(10), С. 4784 - 4790

Опубликована: Март 5, 2025

A novel magnetic hollowed CoFe@C-650 prism catalyst has been successfully prepared and applied in the N-alkylation of alcohols amines through a hydrogen borrowing strategy. The demonstrates good to excellent activities reaction with broad substrate scope afford up 99% yield target products. preliminary mechanistic study reveals that high valent Co species may promote adsorption conversion alcohols, while Fe assists hydrogenating imine intermediates.

Язык: Английский

Процитировано

0

Electro-Oxidative Three-Component Synthesis of 3,5-Disubstituted-1,2,4-Thiadiazoles from Amines, Amidines, and CS2 DOI
Peng‐Fei Huang, Ying Peng,

Jia-Le Fu

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 29, 2025

1,2,4-Thiadiazoles, a significant class of heterocyclic compounds, are widely found in biologically active molecules. Herein, we report green electrochemical three-component reaction amines, amidines, and CS2 for the effective synthesis 3,5-disubstituted-1,2,4-thiadiazoles under metal- oxidant-free conditions. Both aliphatic aryl amines well-tolerated at room temperature simple undivided cell. A series 1,2,4-thiadiazoles prepared with excellent functional groups.

Язык: Английский

Процитировано

0

Base-promoted ring-opening/recyclization of naphthoquinones to access benzo[5,6][1,4]thiazino[4,3-b]isoquinoline-7,12-diones at room temperature DOI
Bin Tan,

Zhuoqin Li,

Xinlin Zhou

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(17), С. 4779 - 4784

Опубликована: Янв. 1, 2024

A novel and unique nitrogen atom insertion into naphthoquinone rings to construct structurally valuable polycyclic heterocycles at room temperature under transition-metal-free conditions has been described.

Язык: Английский

Процитировано

2

Base-Promoted Tandem Cyclization of 2-(Indol-3-yl)naphthoquinones with Benzamidines toward Polysubstituted Pyrimido[4,5-b]indoles DOI
Bin Tan, Kai Hu, Chao Zhang

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Сен. 19, 2024

A novel and unique approach for the construction of polysubstituted pyrimido[4,5-

Язык: Английский

Процитировано

1

Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles DOI
Peng‐Fei Huang,

Jia-Le Fu,

Ying Peng

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(18), С. 3752 - 3760

Опубликована: Янв. 1, 2024

2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur as source. Both aliphatic amines aryl demonstrate good compatibility at room temperature, highlighting broad group tolerance this approach. Additionally, selenium demonstrated reactivities comparable to those sulfur.

Язык: Английский

Процитировано

0