AJP Cell Physiology,
Год журнала:
2023,
Номер
326(1), С. C74 - C88
Опубликована: Ноя. 20, 2023
We
demonstrate
the
expression
and
function
of
voltage-gated
delayed
rectifier
potassium
channel
Kv2
in
vagal
nodose
neurons.
Within
sensory
neurons,
channels
limit
width
broader
C-type
but
not
narrow
A-type
action
potential.
nucleus
solitary
tract
(nTS),
location
terminal
field,
does
influence
glutamate
release.
However,
limits
potential
discharge
nTS
relay
These
data
suggest
a
critical
role
for
vagal-nTS
reflex
arc.
Frontiers in Neurology,
Год журнала:
2023,
Номер
14
Опубликована: Окт. 6, 2023
Respiratory
difficulties
and
mortality
following
severe
cervical
spinal
cord
injury
(CSCI)
result
primarily
from
malfunctions
of
respiratory
pathways
the
paralyzed
diaphragm.
Nonetheless,
individuals
with
CSCI
can
experience
partial
recovery
function
through
neuroplasticity.
For
decades,
researchers
have
revealed
potential
mechanism
nerve
plasticity
after
CSCI,
made
progress
in
tissue
healing
functional
recovery.
While
most
existing
studies
on
injuries
focused
cord,
there
is
a
paucity
research
respiratory-related
brain
structures
such
injuries.
Given
interconnectedness
brain,
traumatic
changes
to
former
also
impact
latter.
Consequently,
are
other
therapeutic
targets
consider?
This
review
introduces
anatomy
physiology
typical
centers,
explores
alterations
injuries,
delves
into
structural
foundations
modified
patients
CSCI.
Additionally,
we
propose
that
magnetic
resonance
neuroimaging
holds
promise
study
post-CSCI.
By
studying
hope
guide
future
clinical
work.
Experimental Physiology,
Год журнала:
2023,
Номер
109(12), С. 2001 - 2005
Опубликована: Сен. 26, 2023
Abstract
Patients
diagnosed
with
heart
failure
have
high
rates
of
mortality
and
morbidity.
Based
on
promising
preclinical
studies,
vagal
nerve
stimulation
has
been
trialled
in
these
patients
using
whole
electrical
stimulation,
but
the
results
mixed.
This
is,
at
least
part,
due
to
an
inability
selectively
recruit
activity
specific
fibres
within
vagus
as
well
not
knowing
which
‘therapeutic’
are.
symposium
review
focuses
a
population
cardiac‐projecting
efferent
cell
bodies
located
dorsal
motor
nucleus
new
method
targeting
projections
potential
treatment
failure.
AJP Cell Physiology,
Год журнала:
2023,
Номер
326(1), С. C74 - C88
Опубликована: Ноя. 20, 2023
We
demonstrate
the
expression
and
function
of
voltage-gated
delayed
rectifier
potassium
channel
Kv2
in
vagal
nodose
neurons.
Within
sensory
neurons,
channels
limit
width
broader
C-type
but
not
narrow
A-type
action
potential.
nucleus
solitary
tract
(nTS),
location
terminal
field,
does
influence
glutamate
release.
However,
limits
potential
discharge
nTS
relay
These
data
suggest
a
critical
role
for
vagal-nTS
reflex
arc.
