Nickel-Catalyzed Alkylation of Oxindoles with Secondary Alcohols DOI
Atanu Bera, Adrija Ghosh, Debasis Banerjee

и другие.

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(11), С. 7162 - 7171

Опубликована: Май 10, 2023

Herein, we have demonstrated a simple nickel-catalyzed C-3-selective alkylation of 2-oxindoles using wide variety secondary alkyl alcohols. As special highlight, functionalization the cholesterol derivative was reported. Control experiments, initial mechanistic studies, and deuterium-labeling experiments were performed for process.

Язык: Английский

Manganese-Catalyzed C(α)-Alkylation of Oxindoles with Secondary Alcohols via Borrowing Hydrogen DOI
Jagannath Rana,

Palaniyappan Nagarasu,

Murugan Subaramanian

и другие.

Organometallics, Год журнала: 2021, Номер 40(6), С. 627 - 634

Опубликована: Март 3, 2021

A general and efficient C(α)-alkylation of oxindoles with unactivated secondary alcohols as alkylating agents catalyzed by a newly developed NNN-Mn(II) complex is reported. Mechanistic studies illustrate that the importance NH moiety in M–L cooperation play very important roles during catalytic transformation.

Язык: Английский

Процитировано

31
One-Pot Conversion of Allylic Alcohols to α-Methyl Ketones via Iron-Catalyzed Isomerization–Methylation DOI Creative Commons

Daniel E. Latham,

Kurt Polidano,

Jonathan M. J. Williams

и другие.

Organic Letters, Год журнала: 2019, Номер 21(19), С. 7914 - 7918

Опубликована: Сен. 19, 2019

A one-pot iron-catalyzed conversion of allylic alcohols to α-methyl ketones has been developed. This isomerization–methylation strategy utilized a (cyclopentadienone)iron(0) carbonyl complex as precatalyst and methanol the C1 source. diverse range undergoes form in good isolated yields (up 84% yield).

Язык: Английский

Процитировано

31
(Cyclopentadienone)iron Complexes: Synthesis, Mechanism and Applications in Organic Synthesis DOI

Monalisa Akter,

Pazhamalai Anbarasan

Chemistry - An Asian Journal, Год журнала: 2021, Номер 16(13), С. 1703 - 1724

Опубликована: Май 17, 2021

(Cyclopentadienone)iron tricarbonyl complexes are catalytically active, inexpensive, easily accessible and air-stable that extensively studied as an active pre-catalyst in homogeneous catalysis. Its versatile catalytic activity arises exclusively due to the presence of a non-innocent ligand, which can trigger its unique redox properties effectively. These have been employed widely (transfer)hydrogenation (e. g., reduction polar multiple bonds, Oppenauer-type oxidation alcohols), C-C C-N bond formation reductive aminations, α-alkylation ketones) other synthetic transformations. In this review, we discuss remarkable advancement various applications along with synthesis mechanistic studies, until February 2021.

Язык: Английский

Процитировано

24
Transition metal-free functionalization of 2-oxindolesviasequential aldol and reductive aldol reactions using rongalite as a C1 reagent DOI

Sivaparwathi Golla,

Swathi Jalagam,

Soumya Poshala

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2022, Номер 20(24), С. 4926 - 4932

Опубликована: Янв. 1, 2022

Rongalite induced transition metal and hydride-free reductive aldol reaction is developed for 3-methylindoline-2-ones 3-(hydroxymethyl)-3-methylindolin-2-ones from 2-oxindoles. Here, plays a key role of being reductant C1 source.

Язык: Английский

Процитировано

18
Nickel-Catalyzed Alkylation of Oxindoles with Secondary Alcohols DOI
Atanu Bera, Adrija Ghosh, Debasis Banerjee

и другие.

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(11), С. 7162 - 7171

Опубликована: Май 10, 2023

Herein, we have demonstrated a simple nickel-catalyzed C-3-selective alkylation of 2-oxindoles using wide variety secondary alkyl alcohols. As special highlight, functionalization the cholesterol derivative was reported. Control experiments, initial mechanistic studies, and deuterium-labeling experiments were performed for process.

Язык: Английский

Процитировано

10