Crystal Growth & Design,
Год журнала:
2024,
Номер
25(2), С. 444 - 451
Опубликована: Дек. 25, 2024
Solid-state
synthesis
is
an
approach
to
organic
that
desirable
because
it
can
offer
minimal
or
no
solvent
waste,
high
yields,
and
relatively
low
energy
footprints.
Herein,
we
report
the
solid-state
of
a
novel
Schiff
base,
4-{(E)-[(4-methylpyridin-3-yl)imino]methyl}benzoic
acid
(4-PIBZ),
synthesized
through
reaction
amine
aldehyde.
4-PIBZ
was
prepared
via
solvent-drop
(water)
grinding
(SDG)
on
multigram
scale
with
97%
yield
characterized
using
FTIR,
1H
NMR,
SCXRD.
The
pyridyl
carboxylate
moiety
present
in
make
suitable
for
use
as
linker
ligand
indeed
found
coordinate
Cu(II),
Zn(II),
Cd(II)
cations,
enabling
serve
assembly
coordination
polymers.
thereby
formed
1D
(spiro
chain)
2D
(square
lattice,
sql,
topology)
polymers
solvent-induced
(layering
slurry)
methods.
resulting
were
though
X-ray
diffraction
(SCXRD,
PXRD)
TGA,
further
demonstrating
utility
green
methods
preparation
some
classes
new
ligands
turn
be
used
The Journal of Physical Chemistry Letters,
Год журнала:
2024,
Номер
15(26), С. 6880 - 6889
Опубликована: Июнь 27, 2024
Perovskite
solar
cells
(PSCs)
represent
a
promising
avenue
for
producing
cost-effective
energy
by
harnessing
sunlight,
but
challenges
persist
in
their
solution
processing,
which
uses
large
amount
of
organic
solvent
existing
PSC
technology.
The
use
water
as
offers
an
environmentally
friendly
alternative
to
traditional
solvents,
aligning
with
the
global
drive
sustainable
renewable
technologies.
This
Perspective
provides
overview
research
area
fabrication
using
solvent,
highlighting
key
advancements
synthesis
process.
We
delve
into
kinetics
crystallization
and
physical-chemical
transformations
perovskite
materials
water-based
processing.
Key
scalability
processing
are
discussed.
sheds
light
on
broader
potential
enhancing
ecofriendliness
cell
Royal Society of Chemistry eBooks,
Год журнала:
2024,
Номер
unknown, С. 50 - 84
Опубликована: Окт. 18, 2024
Solid-phase
peptide
synthesis
(SPPS)
is
a
ubiquitous
methodology
for
making
peptides
from
R&D
to
manufacturing
plant,
not
least
in
the
context
of
using
and
peptidometics
as
pharmaceuticals.
Nevertheless,
SPPS
has
long
been
plagued
by
its
reliance
on
large
amounts
hazardous
materials
such
dimethylformamide
solvent
trifluoroacetic
acid
cleavage
reagent.
Consequently,
with
methods
producing
sustainable
manner
being
high
demand,
numerous
reports
covering
various
aspects
greening
have
appeared
recent
years.
In
this
chapter,
an
integrated
overview
state-of-the-art
field
presented,
highlighting
advances
within
entire
workflow
starting
amino
coupling
cycle
cleaving
off
polymer
support.
Greener
assembly
complex
waste
minimization
tactics
are
also
delineated,
together
discussion
adoption
practice,
scale-up,
procurement,
costs
intellectual
property
key
considerations
attaining
truly
SPPS.
Finally,
perspective
future
directions
towards
elevating
versatile,
platform
provided.
Organic Letters,
Год журнала:
2024,
Номер
26(15), С. 3284 - 3288
Опубликована: Март 28, 2024
This
work
reports
the
first
solvent-free
catalytic
approach
for
cleavage
of
fluorenylmethoxycarbonyl
(Fmoc)
protecting
group
from
amine
and
alcohol
functionalities.
Various
saccharide,
peptide,
glyco-amino
acid
substrates
were
efficiently
deprotected
by
simple
treatment
with
20
mol
%
neat
4-dimethylaminopyridine
(DMAP)
(one
effective
base
catalysts
found),
without
any
solvent
or
stoichiometric
additives.
Small
model
structures
finally
assembled
through
one-pot,
base-catalyzed,
multistep
sequences
combining
Fmoc
esterification,
amidation,
and/or
glycosylation
steps.
Organic Letters,
Год журнала:
2024,
Номер
26(31), С. 6787 - 6791
Опубликована: Июль 29, 2024
The
widely
used
Fmoc/t-Bu
solid-phase
peptide
synthesis
(SPPS)
is
hampered
by
relying
on
corrosive,
per/polyfluoroalkyl
substance
(PFAS)
classified
trifluoroacetic
acid
(TFA)
as
a
universal
protecting
group
(PG)
removal/resin
cleavage
reagent.
We
report
that
suitable
combinations
of
Brønsted
acids
(BAs)
and
Lewis
(LAs)
such
HCl/FeCl3
AcOH/FeCl3
constitute
viable
alternatives
for
TFA
PFAS-free
agents.
Using
water
miscible
dimethyl
carbonate
(DMC)
acetonitrile
(MeCN)
solvents
enabled
diluting
mixtures
with
aqueous
solutions,
allowing
direct
use
in
purification
which
removal
>99.99%
iron
from
an
induced
was
demonstrated.
ACS Applied Energy Materials,
Год журнала:
2024,
Номер
7(22), С. 10212 - 10229
Опубликована: Ноя. 11, 2024
The
breakthrough
in
2012
showed
how
next-generation
solar
cells
lead
to
perovskite-based
materials
and
devices.
Perovskite
(PSCs)
have
achieved
power
conversion
efficiency
(PCE)
∼26.1%
on
rigid
∼25.09%
flexible
substrates.
long
lifetime
of
∼8760
h
is
reported
for
PSCs
using
Pb-based
perovskites
as
an
absorber.
However,
the
question
Pb
toxicity
still
a
major
issue
commercialization
path.
poor
stability
Pb-related
hinder
their
industrial
applications.
various
efforts
from
past
decade
resulted
development
tin
halide
perovskites,
defect-structured
double
perovskite-inspired
such
rudorffites.
PCE
these
newly
developed
falls
short
that
corresponding
Pb-halide-based
perovskites.
Hence,
herein,
review
present
status
Pb-free
perovskite
related
cell
devices
will
be
discussed.
Further,
summarize
recent
developments
free
useful
cells.
Sn-,
Ge-,
Sb-,
Bi-based
combinations
would
explored
futuristic
use
In
summary,
latest
progress,
outstanding
challenges,
future
directions
thin
films,
nanocrystals
also
reviewed.
focus
optical
optoelectronic
properties
give
researchers
today
tomorrow
who
are
working
field
may
join
shortly.
Organic Process Research & Development,
Год журнала:
2024,
Номер
28(12), С. 4501 - 4512
Опубликована: Дек. 10, 2024
Peptide
therapeutics
have
exploded
in
popularity
recent
years,
motivating
the
need
for
advanced
manufacturing
methods
which
can
be
applied
across
solid-phase
peptide
synthesis
(SPPS)
process.
The
Food
and
Drug
Administration's
Process
Analytical
Technology
(PAT)
initiative
offers
a
platform
to
implement
improve
efficiency
understanding
of
pharmaceutical
processes
shows
great
promise
application
toward
industrial
SPPS.
In
this
work,
Raman
spectroscopy
was
used
as
main
PAT
tool
on-line
real-time
monitoring
entire
SPPS
process,
from
Fmoc
removal,
coupling,
through
extensive
solvent-washing
steps.
is
rapid,
specific,
nondestructive
technique
that
provide
rich
information
solvent
use
save
process
time.
Specifically,
work
reports
on
development
amino
acid
coupling
during
stage
residual
piperidine
concentration
post-deprotection
washing
SPPS,
help
reduce
better
understand
reaction
its
time
frame.
We
show
significant
reduction
possible
by
employing
along
with
partial
least
squares
model
predict
real
continuous
wash.
addition,
greater
kinetics
could
lead
improvements
total
Nanoscale,
Год журнала:
2024,
Номер
16(20), С. 9742 - 9747
Опубликована: Янв. 1, 2024
Heterobimetallic
Pt(II)/Cu(II)
single-chain
polymer
nanoparticles
(SCNPs)
were
sequentially
synthesized
from
a
polymeric
precursor
featuring
both
α-diazo-β-ketoester
and
naked
β-ketoester
functional
groups.
Photoactivated
carbene
generation
at
λexc
=
365
nm
moieities
was
triggered
for
bonding
Pt(II)
ions
dichloro(1,5-cyclooctadiene)Pt(II)
to
the
precursor,
whereas
Cu(II)
subsequently
incorporated
via
Cu(II)-(β-ketoester)2
complex
formation
using
acetate.
Both
intrachain
complexation
found
contribute
folding
of
generating
Pt(II)/Cu(II)-SCNPs
as
evidenced
by
infrared
spectroscopy,
size
exclusion
chromatography
dynamic
light
scattering.
These
heterobimetallic
SCNPs
proved
highly
efficient
soft
nanocatalysts
consecutive
one-pot
alkyne
semihydrogenation/alkene
dioxygenation
reactions
room
temperature
in
N-butylpyrrolidone,
non-toxic
alternative
solvent
N,N-dimethylformamide.
