Catalyst- and Solvent-Free Hydrosulfonylation of Alkenes with Sulfinates Enabling Green Synthesis of β-Sulfonyl Amides

Tetrahedron, Год журнала: 2025, Номер unknown, С. 134632 - 134632

Опубликована: Март 1, 2025

Язык: Английский

Direct Photoactivation of Sulfinic Acids to Access Hydrosulfonylation and Arylsulfonylation of Alkenes

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 2, 2025

Simple and atom-economical hydrosulfonylation arylsulfonylation of alkenes have been developed using sulfinic acid as both the sulfonyl group source hydrogen atom donor under light irradiation. These reactions feature catalyst-, oxidant-, additive-free conditions, offering a highly practical approach for synthesis diversely functionalized sulfones. Preliminary mechanistic studies indicate that these proceed via photoactivation to generate radical, followed by radical chain process.

Язык: Английский

Visible‐Light‐Initiated Uranyl‐Catalyzed Hydrosilylation and Hydrosulfonylation of Alkenes and Alkynes

Advanced Synthesis & Catalysis, Год журнала: 2024, Номер unknown

Опубликована: Авг. 27, 2024

Abstract This study investigates the visible‐light‐initiated uranyl(VI)‐catalyzed activation of Si−H bonds through direct hydrogen atom transfer, which facilitates formation silyl radicals from silanes. The radical can abstract a chlorine sulfonyl chloride, leading to generation radicals. These and could react with alkenes alkynes, achieving first example uranyl‐catalyzed hydrosilylation hydrosulfonylation unsaturated C−C bonds. method features mild reaction conditions broad substrate scope, exhibits exceptional functional‐group tolerance. Consequently, it is suitable for late‐stage functionalization drug derivatives.

Язык: Английский