Obesity,
Год журнала:
2021,
Номер
30(2), С. 482 - 490
Опубликована: Дек. 28, 2021
The
present
study
aimed
to
investigate
the
associations
of
cholecystectomy
with
low
muscle
mass,
strength,
sarcopenia,
and
sarcopenic
obesity.This
population-based
included
data
from
4,909
participants
aged
18
80
years.
History
was
diagnosed
using
abdominal
ultrasonography.
Muscle
mass
evaluated
a
dual-energy
x-ray
absorptiometry
scan,
strength
an
electronic
hand
dynamometer.
Sarcopenia
defined
as
presence
both
strength.
Sarcopenic
obesity
sarcopenia
obesity.
Multivariable
logistic
regression
models
were
performed
obesity.Participants
history
more
likely
than
those
without
have
sarcopenia.
Furthermore,
compared
that
occurred
within
7
years
(7
is
median
interval
between
physical
examination),
ago
had
higher
odds
Finally,
whether
by
BMI
or
body
fat
percentage,
positively
associated
obesity.Cholecystectomy
PeerJ,
Год журнала:
2022,
Номер
10, С. e14429 - e14429
Опубликована: Ноя. 23, 2022
Background
Sarcopenia
is
prevalent
and
associated
with
the
occurrence
of
cardiovascular
complications
in
patients
undergoing
maintenance
hemodialysis
(MHD).
It
unknown
how
skeletal
muscle
may
be
aspects
myocardial
structure
function.
This
study
aimed
to
evaluate
association
between
sarcopenia
cardiac
function
MHD.
We
also
examined
prognostic
role
for
mortality
events
(CVE)
this
population.
Methods
Participants
from
a
single
center
underwent
bioimpedance
body
composition
analysis
measure
echocardiography
assess
was
diagnosed
based
on
Asian
Working
Group
criteria.
The
end
points
were
all-cause
CVE.
Results
Of
158
participants,
46
(29.1%)
had
sarcopenia,
102
(64.6%)
left
ventricular
diastolic
dysfunction
(LVDD),
106
(67.0%)
hypertrophy
(LVH).
smaller
right
sizes
(2.54
±
0.77
vs
2.76
0.28;
P
<
0.01),
inter-ventricular
thickness
(1.07
0.19
1.14
0.20;
=
0.039),
posterior
wall
(0.96,
0.89–1.10
1.06,
0.95–1.20;
0.018).
Skeletal
mass
strongly
correlated
(LVM)
(r
0.577;
0.0001).
Furthermore,
risk
LVDD
(OR:
4.92,
95%
confidence
interval
(CI)
[1.73–13.95])
LVH
4.88,
CI
[1.08–21.96])
much
higher
sarcopenic
group
than
non-sarcopenic
group.
During
follow-up
period
18
months,
11
(6.9%)
died,
which
seven
died
(4.4%)
CVE,
36
(22.8%)
experienced
presence
(adjusted
hazard
ratio
(HR),
6.59;
[1.08–39.91];
0.041)
low
index
(HR,
3.41;
[1.01–11.57];
0.049)
handgrip
strength
0.88;
[0.78–0.99];
0.037)
independently
predicted
death.
significant
predictor
CVE
10.96;
[1.14–105.10];
0.038).
Conclusion
Our
findings
demonstrated
that
LVH,
probability
death
Diabetes/Metabolism Research and Reviews,
Год журнала:
2024,
Номер
40(2)
Опубликована: Фев. 1, 2024
Abstract
Aims
The
impact
of
donor
abdominal
fat‐to‐muscle
ratio
(FMR)
on
kidney
transplant
(KT)
outcomes
was
assessed.
Given
the
transient
nature
donor's
metabolic
environment
in
recipients,
this
study
investigated
capacity
body
composition
to
induce
memory
effects.
Materials
and
Methods
KT
patients
(
n
=
895)
who
received
allografts
from
living
donors
(2003–2013)
were
included.
Donor
fat
muscle
quantified
using
pre‐KT
computed
tomography
scans.
Patients
categorised
into
FMR
tertiles
followed
up
for
graft
outcomes.
Additionally,
genome‐wide
DNA
methylation
analysis
performed
28
samples
low‐
high‐FMR
groups.
Results
Mean
recipient
age
42.9
±
11.4
years
60.9%
males.
averaged
1.67
0.79.
Over
a
median
120.9
42.5
months,
failure
127)
death‐censored
109)
more
frequent
higher
tertiles.
Adjusted
hazard
ratios
highest
versus
lowest
tertile
1.71
(95%
CI,
1.06–2.75)
overall
1.90
1.13–3.20)
failure.
Genome‐wide
identified
58
differentially
methylated
regions
p
<
0.05,
|Δ
β
|
>
0.2)
35
genes
showed
differential
between
high‐
(FMR
>1.91)
low‐FMR
<1.27)
Conclusions
Donors
with
increased
reduced
may
negatively
allograft
survival
possibly
through
transmission
epigenetic
changes,
implying
body‐composition‐related
effect.
Clinical Medicine Insights Endocrinology and Diabetes,
Год журнала:
2024,
Номер
17
Опубликована: Янв. 1, 2024
Objective:
There
is
no
study
on
the
relationship
between
triglyceride-glucose
index
(TyG
index)
and
skeletal
muscle
mass
in
middle-aged
elderly
C
population.
Therefore,
aim
of
to
investigate
TyG
weight-adjusted
relative
(RSMI)
Methods:
We
retrospectively
studied
947
aged
⩾40
years
subjects
who
got
a
routine
medical
examination
Department
Geriatrics
R
Hospital
from
May
2021
March
2023.
The
RSMI
was
designed
evaluate
calculated
based
lean
limbs(kg)/body
weight(kg)
×
100%.
Skeletal
reduction
defined
as
1-2
standard
deviations
(SD)
below
healthy
adults
30-49
old.
Considering
quartile
groups
index,
were
assigned
4
groups:
Q1
(less
than
or
equal
8.171),
Q2
(from
8.172
8.569),
Q3
8.570
8.992),
Q4
(greater
8.993).
Results:
With
increased,
levels
significantly
reduced(
P
<
.001).
Spearman’s
correlation
analysis
showed
that
negatively
correlated
with
males
(r
=
−0.320)
females
−0.240).
positively
body
(BMI),
systolic
blood
pressure
(SBP),
diastolic
(DBP),
triglyceride
(TG),
total
cholesterol
(TC),
low-density
lipoprotein
(LDL-C),
fasting
plasma
glucose
(FPG),
alanine
aminotransferase
(ALT),
aspartate
(AST)
(
.05).
Besides,
binary
logistic
regression
risk
developing
reduced
group
2.131
(95%CI:1.118-4.064)
males;
2.472
(95%CI:1.581-3.867)
compared
group.
Conclusion:
higher
associated
development
independently
other
influencing
factors.
promises
be
predictor
loss.
Obesity,
Год журнала:
2021,
Номер
30(2), С. 482 - 490
Опубликована: Дек. 28, 2021
The
present
study
aimed
to
investigate
the
associations
of
cholecystectomy
with
low
muscle
mass,
strength,
sarcopenia,
and
sarcopenic
obesity.This
population-based
included
data
from
4,909
participants
aged
18
80
years.
History
was
diagnosed
using
abdominal
ultrasonography.
Muscle
mass
evaluated
a
dual-energy
x-ray
absorptiometry
scan,
strength
an
electronic
hand
dynamometer.
Sarcopenia
defined
as
presence
both
strength.
Sarcopenic
obesity
sarcopenia
obesity.
Multivariable
logistic
regression
models
were
performed
obesity.Participants
history
more
likely
than
those
without
have
sarcopenia.
Furthermore,
compared
that
occurred
within
7
years
(7
is
median
interval
between
physical
examination),
ago
had
higher
odds
Finally,
whether
by
BMI
or
body
fat
percentage,
positively
associated
obesity.Cholecystectomy