Resting-state functional brain connectivity in female adolescents with first-onset anorexia nervosa

NeuroImage Clinical, Год журнала: 2025, Номер unknown, С. 103745 - 103745

Опубликована: Янв. 1, 2025

Women with anorexia nervosa (AN) have been shown to demonstrate differences in functional connectivity brain regions associated cognitive control, somatosensory processing, and emotion regulation. However, previous studies conducted on small samples inconsistent findings. Therefore, this study aimed identify aberrant networks related the core clinical symptoms of AN explore longitudinal association outcome a large population adolescents experiencing their first episode AN. Functional MRI (fMRI) resting-state (RS-FC) female first-onset (n = 56) were compared age- education-matched typically developing (TD) 64). To account for severity underweight, separate analyses performed investigate RS-FC between underweight participants TD adolescents, as well 30) weight-restored 26) participants. Clinical outcomes, i.e. body mass index eating disorder (ED) symptoms, assessed at baseline one-year follow-up. Independent component (ICA) used extract interest: default mode (DMN), left right frontoparietal (FPN), insular (IN) networks. Linear regression assess participants, whether was Two statistical models used: model 1 adjusted age socioeconomic status (SES), 2 additionally anxiety depressive symptoms. Underweight had lower DMN-IN, FPN-IN adolescents. After correction multiple testing, no significant found whole group group. not nor is changes DMN-IN during state. These longer observed emphasizing impact Changes these may partly explain impaired control difficulties behavioral regulation individuals

Язык: Английский

Altered value-based decision-making in anorexia nervosa: A systematic review

Neuroscience & Biobehavioral Reviews, Год журнала: 2024, Номер unknown, С. 105944 - 105944

Опубликована: Ноя. 1, 2024

Язык: Английский