Silver N-Heterocyclic Carbene (NHC) Complexes as Antimicrobial and/or Anticancer Agents DOI Creative Commons
Jessica Ceramella, Alessia Catalano, Annaluisa Mariconda

и другие.

Pharmaceuticals, Год журнала: 2024, Номер 18(1), С. 9 - 9

Опубликована: Дек. 25, 2024

The strict connections/interactions between microbial infections and cancer are nowadays widely accepted. Hence, the dual (or multiple) targeting of is an essential issue to be addressed. In this context, metal complexes have gained considerable importance effectiveness in medicinal chemistry. Particularly, N-heterocyclic carbene (NHC) with transition metals emerged as very promising compounds. Among myriad NHC–metal complexes, those bearing silver will subject review. Numerous Ag(I)-NHC revealed high antibacterial and/or anticancer properties, even higher than reference drugs. Herein, we summarize most recent studies while also discussing proposed mechanism action offering interesting remark about research field. Literature databases (PubMed/MEDLINE, Scopus, Google Scholar) were used sources search literature, referring last five years.

Язык: Английский

Silver N-Heterocyclic Carbene (NHC) Complexes as Antimicrobial and/or Anticancer Agents DOI Creative Commons
Jessica Ceramella, Alessia Catalano, Annaluisa Mariconda

и другие.

Pharmaceuticals, Год журнала: 2024, Номер 18(1), С. 9 - 9

Опубликована: Дек. 25, 2024

The strict connections/interactions between microbial infections and cancer are nowadays widely accepted. Hence, the dual (or multiple) targeting of is an essential issue to be addressed. In this context, metal complexes have gained considerable importance effectiveness in medicinal chemistry. Particularly, N-heterocyclic carbene (NHC) with transition metals emerged as very promising compounds. Among myriad NHC–metal complexes, those bearing silver will subject review. Numerous Ag(I)-NHC revealed high antibacterial and/or anticancer properties, even higher than reference drugs. Herein, we summarize most recent studies while also discussing proposed mechanism action offering interesting remark about research field. Literature databases (PubMed/MEDLINE, Scopus, Google Scholar) were used sources search literature, referring last five years.

Язык: Английский

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