Royal Society of Chemistry eBooks,
Год журнала:
2024,
Номер
unknown, С. 287 - 298
Опубликована: Фев. 21, 2024
Organophosphorus
chemistry
is
a
broad
and
exciting
field,
with
potential
opportunities
for
researchers
involved
in
multi-disciplinary
areas
of
scientific
endeavour,
including
organic,
medicinal,
pharmaceutical,
agricultural,
industrial
chemistry.
compounds
find
extensive
applications
all
these
fields
owing
to
their
inherent
physical
biological
properties.
Since
its
first
development
the
90s,
green
sustainable
has
grown
considerably
over
past
two
decades.
It
become
much
more
prevalent
among
working
branches
chemical
science.
As
part
noteworthy
developments,
synthetic
organic
chemists
have
been
motivated
develop
eco-friendly
methodologies
generating
phosphorus-functionalised
interest,
focusing
on
various
principles.
result,
considerable
progress
towards
accomplished
during
last
decade.
In
continuation
our
earlier
contributions,
this
chapter
also
aims
offer
an
overview
such
developments
approaches
organophosphorus
reported
2021.
Green Chemistry,
Год журнала:
2021,
Номер
24(2), С. 585 - 613
Опубликована: Ноя. 30, 2021
Organophosphorus
compounds
play
an
important
role
in
the
modern
chemical
industry
and
have
a
broad
range
of
applications
as
flame
retardants,
agrochemicals,
warfare
agents.
ACS Omega,
Год журнала:
2025,
Номер
10(17), С. 17887 - 17897
Опубликована: Апрель 25, 2025
Primary
vinylarenes
are
important
monomers
for
the
production
of
materials,
which
in
our
case
ion
exchange
membranes
electrolyzers.
Given
high
cost
certain
but
relative
affordability
their
aldehyde
precursors,
we
explored
synthesis
using
flow
chemistry
to
enable
facile
and
safe
scale-up.
While
a
soluble,
methanolic
Wittig
reaction
found
limited
success,
an
alternative
approach
involving
Peterson
olefination
was
high-yielding.
This
required
(trimethylsilyl)methyl
Grignard
reagent,
generated
magnesium-filled
column.
Thus,
2-vinylthiophene
obtained
93%
yield
at
37
g
scale,
route
applicable
other
nonpolar
arenes.
For
polar
arenes,
precipitation
oxymagnesium
chloride
stage
inefficient
elimination
were
observed,
these
challenges
could
be
mitigated
by
employing
(phenyldimethylsilyl)methyl
reagent
instead
stronger
acid
higher
temperature
elimination.
Metals,
Год журнала:
2025,
Номер
15(5), С. 524 - 524
Опубликована: Май 6, 2025
Organophosphorus
compounds
(OPC)
are
a
large
class
of
organic
that
provide
wide
range
applications,
and
their
importance
has
grown
steadily
in
recent
years.
In
each
category
family,
these
have
similarities
differences.
Due
to
immense
variety,
chemicals
various
properties
and,
therefore,
applications.
fact,
works
been
published
recently
present
the
main
applications
OPC,
especially
metal
extraction.
Despite
extemsive
use,
optimizing
performance
as
extractant
agents
remains
challenge
due
structural
variability
sensitivity
process
parameters.
This
review
provides
critical
analysis
pentavalent
OPCs,
focusing
on
how
chemical
nature
influences
heavy
extraction
efficiency.
For
first
time,
we
novel
classification
system
for
OPCs
based
phosphorus
valency
heteroatom
coordination,
offering
framework
guide
future
research.
Our
findings
reveal
direct
coordination
heteroatoms
such
oxygen,
sulfur,
nitrogen
great
influence
physicochemical
characteristics
observation
is
line
with
Pearson’s
Hard
Soft
Acids
Bases
(HSAB)
theory
sense
it
demonstrates
altering
alters
affinity
ligand.
As
result,
modifications
can
improve
by
up
40%
some
metals,
highlighting
potential
optimized
molecular
designs
maximize
industrial
future,
this
work
offers
solid
foundation
studies
rational
design
organophosphorus-based
extractants.
Using
HSAB
our
system,
researchers
rationally
target
unparalleled
precision.
These
results
transformative
impacts
recovery
efficiency-intensive
sectors
like
mining,
waste
recycling,
clean
energy
technologies.
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 12, 2025
Denton's
redox-neutral
catalytic
Mitsunobu
reaction
is
remarkable
in
that
it
translates
a
traditionally
driven
by
the
consumption
of
sacrificial
chemical
reagents
to
an
additive-free
manifold.
Rational
attempts
improve
system
have
been
met
with
only
marginal
improvements,
and
lack
consensus
concerning
rate-determining
step
continues
limit
effective
development.
Here,
we
analyze
mechanism
focusing
on
critical,
largely
overlooked
element:
removal
water
using
Dean-Stark
apparatus.
Experimental
analysis
process,
coupled
extensive
kinetic
simulations,
demonstrates
overall
rate
intimately
tied
removal.
This
process
can
be
viewed
as
transition
between
potential
energy
surfaces
and,
consequently,
subsequent
steps
progress
spontaneously
absence
water,
allowing
explanation
how
Le
Chatelier's
principle,
thermodynamic
effect,
profound
influence
over
reaction.
We
identify
three
bottlenecks
inform
catalyst
design.
Additionally,
(a)
clarify
ongoing
discussion
regarding
step,
(b)
provide
clear
advice
future
design
taking
into
account
role
(c)
discuss
context
formally
endergonic
esterification
reactions,
noting
parallels
ratchet
mechanisms.
Finally,
highlight
general
principles
catalyst/reaction
emerge
from
our
implement
findings
demonstrate
50%
acceleration
resulting
improved
removal,
substantially
greater
enhancement
than
previously
obtained
computationally
guided
structural
changes.
Chemical Science,
Год журнала:
2021,
Номер
12(21), С. 7561 - 7568
Опубликована: Янв. 1, 2021
An
asymmetric
Michael
addition
of
malononitrile
to
vinyl
phosphonates
was
accomplished
by
hydrogen
bond-enhanced
bifunctional
halogen
bond
(XB)
catalysis.
NMR
titration
experiments
were
used
demonstrate
that
bonding,
with
the
support
hydrogen-bonding,
played
a
key
role
in
activation
acceptors
through
phosphonate
group.
This
is
first
example
use
XBs
for
organophosphorus
compounds
synthesis.
In
addition,
iodo-perfluorophenyl
group
proved
be
better
directing
unit
than
different
iodo-
and
nitro-substituted
phenyl
groups.
The
developed
approach
afforded
products
up
excellent
yields
diastereoselectivities
good
enantioselectivities.
Due
to
its
unique
in‐plane
anisotropic
structure,
high
carrier
mobility,
and
adjustable
direct
bandgap,
2D
black
phosphorus
(BP)
has
emerged
as
an
important
graphene‐like
material
for
various
micro‐
optoelectronic,
energy,
catalytic,
biomedical
applications.
However,
lack
of
environmental
stability
severely
limits
processing
in
ambient
conditions.
Chemical
functionalization
is
effective
method
increasing
the
material.
Herein,
main
approaches
chemical
BP
with
organic
inorganic
substrates,
well
routes
preparation
0D/2D
2D/2D
heterostructures,
are
discussed.
Furthermore,
recent
advances
BP‐based
materials
energy
catalysis
fields
summarized.
Finally,
challenges
future
prospects
also
highlighted.
