Recent Developments of Palladium- and Rhodium-Catalyzed β-Carbon Elimination Strategies
Synthesis,
Год журнала:
2023,
Номер
55(15), С. 2285 - 2303
Опубликована: Янв. 22, 2023
Abstract
The
activation
of
C–C
bonds
via
transition
metal
catalysis
has
become
an
increasingly
popular
strategy
in
organic
synthesis.
An
emerging
method
to
cleave
is
facilitate
a
β-carbon
elimination
using
rhodium
or
palladium
catalysis.
This
elementary
step
typically
relies
on
thermodynamic
driving
force,
such
as
the
relief
ring
strain
steric
strain.
More
recently,
use
neopentyl
species
chelation
assistance
enabled
this
difficult
transformation.
review
will
cover
recent
synthetic
applications
eliminations
under
and
1
Introduction
2
Chelation-Assisted
β-Carbon
Elimination
Reactions
3
from
Neopentyl–Pd
Species
4
Pd-Catalyzed
Catellani
5
Cyclopropanes
6
Conclusion
Язык: Английский
Rh(III)-Catalyzed Dienylation and Cyclopropylation of 1,2,3-Benzotriazinones with Alkylidenecyclopropanes
Organic Letters,
Год журнала:
2023,
Номер
25(28), С. 5179 - 5184
Опубликована: Июль 6, 2023
Rh
(III)-catalyzed
dienylation
and
cyclopropylation
of
1,2,3-benzotriazinones
with
alkylidenecyclopropanes
(ACPs)
has
been
achieved.
Different
from
the
previous
reports
1,2,3-benzotriazinones,
triazinone
ring
remained
intact
in
this
C-H
bond
functionlization
reaction.
Also,
denitrogenative
could
also
be
realized
by
changing
reaction
temperature.
This
protocol
is
featured
high
E
selectivity,
wide
substrate
scope,
divergent
structures
products.
Язык: Английский
Rh(iii)-Catalyzed dienylation and cyclopropylation of indoles at the C4 position with alkylidenecyclopropanes
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(16), С. 4287 - 4293
Опубликована: Янв. 1, 2022
Herein,
we
report
a
Rh(
iii
)-catalyzed
C–H
functionalization
of
indoles
at
the
C4
position
with
alkylidenecyclopropanes
(ACPs).
Язык: Английский
Transition Metal‐Catalyzed C2 and C3 Functionalization of Indoles
Опубликована: Март 25, 2023
Transition
metal-catalyzed
C2
and
C3
functionalization
of
indoles
has
been
summarized
in
this
article.
This
chapter
encompasses
a
wide
range
useful
directed
non-directed
transformations.
article
highlights
selective
with
respect
to
C–H
arylation,
alkenylation,
alkynylation,
acylation,
nitration,
borylation,
annulations,
amidation
using
coupling
partners.
Язык: Английский
Synthesis of Indolyl‐1,3‐dienes from β ‐Sulphonyl Aldehydes through One‐Pot Sequential Brønsted Acid/Base Catalysis
European Journal of Organic Chemistry,
Год журнала:
2022,
Номер
2022(18)
Опубликована: Апрель 8, 2022
Abstract
Introduction
of
a
1,3‐diene
moiety
at
the
C3‐position
pyrrole
and
indole
bearing
various
aliphatic
as
well
aromatic
functional
groups
with
good
stereoselectivity
remains
challenging
task.
Keeping
synthetic
applicability
in
mind,
an
eccentric
strategy
is
developed
to
synthesize
1,3‐dienyl
pyrroles
indoles
from
unprotected
employing
β‐sulphonyl
aldehyde
dienylating
agent.
This
method
by
using
one‐pot
sequential
Brønsted
acid/base
catalysis
strategy.
The
nucleophilicity
transmitted
through
conjugation
eliminate
sulfonyl
step‐wise
manner.
Further,
this
protocol
was
extended
incorporation
1,3,5‐triene
unprecedented
successive
three
group
elimination.
As
application
strategy,
Diels−Alder
reaction
hydrothiolation
were
demonstrated.
Язык: Английский