Molecular Catalysis, Год журнала: 2023, Номер 545, С. 113185 - 113185
Опубликована: Май 16, 2023
Язык: Английский
European Journal of Organic Chemistry, Год журнала: 2022, Номер 26(1)
Опубликована: Дек. 9, 2022
Abstract Dual catalysis is one of the most powerful strategies for development chemical reactions in organic synthesis. This strategy can be divided into cooperative catalysis, relay and sequential according to actual mode operation communication between catalysts. In recent years, such has been applied a large number studies since it advantages of: 1) increasing reactivity enabling challenging transformations; 2) offering way controlling stereoselectivity asymmetric reactions, which traditional catalytic systems; 3) catalyze stereodivergent synthesis molecules bearing or more stereocenters from same starting materials. Perspective, intends introduce reader EurJOC special collection on Catalysis , aims summarize different categories dual demonstrate their benefits constructing new bonds selective manner. Finally, current challenges trends will also presented.
Язык: Английский
Процитировано
57
Science China Chemistry, Год журнала: 2023, Номер 66(8), С. 2238 - 2255
Опубликована: Июль 20, 2023
Язык: Английский
Процитировано
19
Green Chemistry, Год журнала: 2024, Номер 26(4), С. 1846 - 1875
Опубликована: Янв. 1, 2024
Organocatalytic enantioselective cross-dehydrogenative coupling reaction provides a great opportunity for the synthesis of highly enantioenriched molecules. In this review, recent progress in field is summarized.
Язык: Английский
Процитировано
7
European Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 2, 2025
Abstract This review collects the recent developments in synthesis of chiral heterocycles through enantioselective silver‐catalyzed transformations published since 2018. It demonstrates power silver catalysts as special mild Lewis acids to provide an impressive diversity reaction pathways, such 1,3‐dipolar cycloadditions, various types cyclizations, along with a wide variety more complex domino/tandem reactions, allowing many novel heterocyclic products be achieved high enantioselectivities.
Язык: Английский
Процитировано
1
Molecules, Год журнала: 2023, Номер 28(6), С. 2694 - 2694
Опубликована: Март 16, 2023
Aldehydes constitute a main class of organic compounds widely applied in synthesis. As such, catalyst-controlled enantioselective α-functionalization aldehydes has attracted great interest over the years. In this context, α-branched are especially challenging substrates because reactivity and selectivity issues. Firstly, transient trisubstituted enamines enolates resulting upon treatment with an aminocatalyst or base, respectively, would exhibit attenuated reactivity; secondly, mixtures E- Z-configured enamines/enolates may be formed; third, effective face-discrimination on such sp2 carbon intermediates by incoming electrophilic reagent is not trivial. Despite these issues, last 15 years, several catalytic approaches for prostereogenic that proceed useful yields diastereo- enantioselectivity have been uncovered. Developments include both organocatalytic metal-catalyzed as well dual catalysis strategies forging new carbon–carbon carbon–heteroatom (C-O, N, S, F, Cl, Br, …) bond formation at Cα starting aldehyde. review, some key early contributions to field presented, but focus most recent methods, mainly covering literature from year 2014 onward.
Язык: Английский
Процитировано
17
Organic Letters, Год журнала: 2024, Номер 26(9), С. 1792 - 1796
Опубликована: Фев. 28, 2024
A mild and effective strategy for the asymmetric synthesis of C2-quaternary indolin-3-ones from 2-alkynyl arylazides ketones by gold/chiral amine relay catalysis is described. In this reaction, undergo gold-catalyzed cyclization, nucleophilic attack, oxidation to form intermediate 2-phenyl-3H-indol-3-ones, followed an l-proline-catalyzed Mannich reaction with ketones, afford corresponding products in satisfactory yields excellent enantio- diastereoselectivities.
Язык: Английский
Процитировано
5
ChemCatChem, Год журнала: 2023, Номер 15(14)
Опубликована: Июнь 14, 2023
Abstract Radical covalent catalysis, namely radical catalysis via a catalyst addition and elimination process, has emerged in the past few decades. This review is aimed to summarize recent advances of by highlighting some outstanding challenges confirming potential areas improvement, which may offer inspiration for future studies.
Язык: Английский
Процитировано
11
Organic Preparations and Procedures International, Год журнала: 2025, Номер unknown, С. 1 - 95
Опубликована: Апрель 11, 2025
Язык: Английский
Процитировано
0
Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(8), С. 1140 - 1146
Опубликована: Март 22, 2023
Abstract Herein, we report synergistic copper/amine‐catalyzed reactions for directly α‐benzylating carbonyl compounds with arylacetic acids. These represent the first examples of decarboxylative oxidative transition‐metal/enamine catalysis α‐functionalizing compounds. The process features starting‐material availability, good functional group tolerance, mild reaction conditions, and good‐to‐excellent yields. Dibenzylated products were formed in moderate yields under slightly altered some transformed into 1,2,3,4‐tetrahydrocyclopenta[ b ]indole derivatives by acid‐catalyzed intermolecular cyclization indoles. Moreover, biological studies revealed that have anticancer properties may be useful drug‐discovery studies. magnified image
Язык: Английский
Процитировано
6
Chemistry - An Asian Journal, Год журнала: 2022, Номер 17(24)
Опубликована: Окт. 22, 2022
Abstract The development of novel methodologies that enable the construction complex chiral molecular scaffolds in an atom and step‐economic manner has always been area immense interest significant synthetic value. transition metal‐catalyzed enantioselective sp 3 C−H activation functionalization reactions serve as expeditious means for introducing diverse functionalities a straightforward manner. However, controlling chemo‐ stereoselectivity these is challenge owing to their ubiquity low reactivity. In this review, we present comprehensive account on recent advances inter‐ intramolecular asymmetric bond utilizing ruthenium, rhodium, iridium catalysts get insights into mechanistic aspects transformations.
Язык: Английский
Процитировано
10