Heteroleptic (NHC/MIC) Biscarbene Ag(I) and Au(I) Complexes: Synthesis, Characterization and Catalytic Applications
ChemPlusChem,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 29, 2025
A
series
of
hetero-biscarbene
silver(I)
and
gold(I)
complexes
the
general
formula
[NHC-M-MIC]PF6
(NHC=imidazol-2-ylidene,
MIC=1,2,3-triazol-5-ylidene)
have
been
prepared
via
treatment
NHC-M-Cl
precursors
in
reaction
with
an
situ
generated
mesoionic
carbene
(MIC).
The
new
heteroleptic
fully
characterized
including
NMR
spectroscopy,
elemental
analysis,
melting
points
single
crystal
X-ray
diffraction.
derivatives
were
employed
successfully
solvent
free
KA2
(ketone-alkyne-amine)
coupling
for
preparation
a
quaternary
carbon-containing
propargyl
amines
while,
biscarbenes,
demonstrated
good
performance
A3
(aldehyde,
amine,
alkyne)
benzylic
oxidation
processes
under
low
catalyst
loadings.
Язык: Английский
Electrochemical Oxidation of Benzyl Alcohols via Hydrogen Atom Transfer Mediated by 2,2,2-Trifluoroethanol
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 29, 2025
We
report
a
novel
electrochemical
oxidation
of
benzyl
alcohols.
found
that
trifluoroethanol
plays
role
as
hydrogen
atom
transfer
(HAT)
mediator,
enabling
the
electron-deficient
substrates
are
difficult
to
directly
oxidize
on
electrode
surfaces.
Density
functional
theory
calculations,
cyclic
voltammetry
measurements,
and
constant
potential
electrolysis
studies
supported
proposed
HAT
mechanism.
Moreover,
obtained
carbonyl
compounds
could
be
functionalized
in
an
one-pot
manner,
further
highlighting
their
synthetic
utility.
Язык: Английский
Electrooxidative Pd-Catalyzed Remote Hydrofunctionalization of Alkenes with Nucleophiles
ACS Catalysis,
Год журнала:
2024,
Номер
14(21), С. 15858 - 15868
Опубликована: Окт. 11, 2024
The
catalytic
hydrofunctionalization
of
alkenes
with
nucleophiles
via
the
generation
carbocationic
intermediates
has
been
extensively
studied
as
an
efficient
strategy
for
regioselective
installation
functional
groups
on
alkene
feedstocks.
However,
since
established
methods
are
confined
to
functionalization
position
where
is
originally
located,
it
highly
desirable
develop
a
broadly
applicable
platform
that
offers
alternative
regioselectivity
otherwise
challenging
achieve
existing
protocols.
Herein,
we
report
remote
method
enabled
by
electrooxidative
palladium
hydride
catalysis.
key
success
formation
carbocation
intermediate
through
mechanistic
pathway,
which
involves
chain-walking
process
followed
anodic
oxidation
organopalladium
species.
This
allows
terminal
and
internal
broad
range
oxygen,
carbon,
nitrogen,
fluoride
nucleophiles,
including
complex
drug-like
molecules.
Язык: Английский