1,3-Thiazole Derivatives as a Promising Scaffold in Medicinal Chemistry: A Recent Overview

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, Год журнала: 2023, Номер 22(3), С. 133 - 163

Опубликована: Сен. 1, 2023

Abstract: The thiazole ring is a unique heterocyclic motif among compounds. This five-member with one nitrogen and sulphur atom displays wide array of pharmacological activities, including anti-inflammatory, antimicrobial, anticancer, antidiabetic, antiviral, etc., by acting on several targets. Its broad range medical applications has inspired us to study this opulent molecule. current review summarizes synthetic approaches for the preparation derivatives in brief discusses promising biological activities scaffold. will be useful drug discovery community facilitate synthesis development novel potent derivatives, which may serve as lead molecules treatment various diseases.

Язык: Английский

Copper-Catalyzed One-Pot Synthesis of N,N-4-Triphenylthiazol-2-amines

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(22), С. 16390 - 16400

Опубликована: Окт. 28, 2024

Herein, we reported an efficient copper-catalyzed strategy for the synthesis of

Язык: Английский