The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(20), С. 15225 - 15233
Опубликована: Окт. 8, 2024
A novel and environmentally friendly photocatalytic strategy is presented for generating acyl radicals from benzoylformic acids, which are subsequently trapped by various sulfone-based SOMOphiles. This provides a robust toolkit to access variety of synthetically important functionalized aryl-ketone derivatives, efficiently directly construct acyl–S, acyl–Se, acyl–C, acyl–N bonds. The broad substrate scope, excellent functional group compatibility, mild reaction conditions make this protocol practical attractive.
Язык: Английский