Vicinal diphosphorylation of enaminones with diaryl phosphine oxides via AlCl3-mediated C N bond cleavage
Tetrahedron Letters,
Год журнала:
2025,
Номер
158, С. 155472 - 155472
Опубликована: Фев. 20, 2025
Язык: Английский
Recent Advances in the Electrochemical Functionalization of Imidazoheterocycles
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 18, 2024
Abstract
Imidazoheterocycles
have
extensive
applications
in
the
pharmaceutical
industry
and
agrochemicals.
A
comprehensive
overview
has
been
provided
on
current
advancements
electrochemical
functionalization
of
imidazo‐fused
heterocycles,
which
classified
into
ten
different
types
reactions.
Electrochemical
synthesis
emerged
as
a
highly
effective
method
for
producing
organic
molecules,
especially
context
sustainable
development.
Employing
electrons
traceless
oxidant,
several
C−H
reactions
heterocycles
achieved
at
either
C3
or
C5
positions.
Electrons
may
serve
reducing
agent
to
synthesize
pyridine
rings
that
are
partially
fully
saturated
imidazo[1,2‐
]pyridines.
The
purpose
review
is
attract
interest
scientific
community
promote
additional
research
imidazoheterocycles
using
methods.
Язык: Английский
Dibromomethane-Triggered Electrochemical Cyclization of Enaminones with Amidines for the Synthesis of 5-Acylimidazoles
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 29, 2024
An
electrochemical
tandem
cyclization
of
enaminones
with
amidines
has
been
reported
for
the
first
time
using
dibromomethane
as
an
initiating
agent
in
undivided
cell.
Following
this
protocol,
a
vast
variety
polysubstituted
5-acylimidazoles
were
obtained
moderate
to
good
yields
without
use
external
oxidants.
Mechanistic
studies
indicate
that
bromide
anion,
electroreductively
generated
from
dibromomethane,
acts
redox
mediator
complete
catalytic
cycle.
Язык: Английский
Divergent Sc(OTf)3‐Catalyzed Tandem Cyclization of o‐Hydroxyphenyl Enaminones with 1,3,5‐Triazinanes: Access to C3‐Aminomethyl Chromones and Tetrahydropyrimidines
Asian Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 9, 2024
Abstract
A
Sc(OTf)
3
‐catalyzed
tandem
cyclization
reaction
of
o
‐hydroxyphenyl
enaminones
with
1,3,5‐triazinanes
has
been
developed
to
generate
two
distinct
annulated
products
in
moderate
good
yields,
which
is
dominated
by
the
electronic
characteristics
1,3,5‐triazinanes.
The
1,3,5‐triaryl‐1,3,5‐triazinane
reacted
as
C−N
synthon
produce
C3‐aminomethyl
chromone,
while
1,3,5‐trialkyl‐1,3,5‐triazinane
acted
C−N−C−N
synthons
deliver
N
,
‐dialkyl
tetrahydropyrimidine
a
free
hydroxyl
group.
Язык: Английский