Exploring the Impact of Click Chemistry on Carbohydrate Derivatives and their Biological Properties DOI Open Access

Dipali G. Pisal,

S. R. Patil,

Chandrashekhar P. Mane

и другие.

Asian Journal of Chemistry, Год журнала: 2025, Номер 37(4), С. 745 - 757

Опубликована: Март 29, 2025

The application of click chemistry in the synthesis intricate carbohydrate derivatives has revolutionized domains chemical biology and synthetic chemistry. This review examines function chemistry, namely copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), effectively altering structures producing practical glycoconjugates. Carbohydrates are essential several biological functions, such as cellular recognition immunological responses, however, their complicated structure makes production difficult. Click provides an optimal answer to these issues due its simplicity, high yields bioorthogonality. methodology been extensively used advancement glycoproteins, glycodendrimers glycopeptides, which play a crucial role fields drug discovery, vaccine development diagnostics. In addition, facilitated biodegradable polymers glycomacromolecules that have potential be materials science, for sustainable smart technology. flexibility accuracy CuAAC carbohydrate-based new opportunities investigation, stimulating advancements both biomedicine industrial applications. evaluation also emphasizes capacity expedite multifunctional therapeutic drugs target ailments like cancer.

Язык: Английский

Cuprous iodide implanted in hot-water-soluble-starch coating of ferrite nanoparticles: efficient catalysts for on–water click synthesis of 1,2,3-triazoles DOI Creative Commons
Mohammad Mousavi, Kurosh Rad‐Moghadam

Nanoscale Advances, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Conglomerates of CuI nanoparticles combined with ferrous ferrite (FF) and cobalt (CF) were obtained using hot-water-soluble starch (HWSS) as a green adhesive possessing strong complexing affinity for both the ferrites nanoparticles. Our findings indicate that size is closely related to nanoparticles, suggesting grafted from HWSS coating The TEM image, histograms derived FE-SEM images XRD patterns resulting composites revealed growth led formation conglomerates not encapsulation More interestingly, impacts oppositely on coercivities ferrites. catalytic efficacy nano-composites, CuI@HWSS@CF CuI@HWSS@FF, in one-pot synthesis 1,2,3-triazoles through click reaction alkyl halides, sodium azide, phenylacetylene "on water" described. use biocompatible nano-catalyst, easy catalyst recycling high yields triazoles within short times are significant advantages synthetic method presented here.

Язык: Английский

Процитировано

0

A sustainable approach for the bis-selenylation of alkynes: Design, synthesis and mechanistic studies DOI
Lucas Martins Correa Böhs,

Calebe Hebrom Livistom Silva,

Natália Emanuele Biolosor Kuntz

и другие.

Tetrahedron Letters, Год журнала: 2025, Номер unknown, С. 155504 - 155504

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Exploring the Impact of Click Chemistry on Carbohydrate Derivatives and their Biological Properties DOI Open Access

Dipali G. Pisal,

S. R. Patil,

Chandrashekhar P. Mane

и другие.

Asian Journal of Chemistry, Год журнала: 2025, Номер 37(4), С. 745 - 757

Опубликована: Март 29, 2025

The application of click chemistry in the synthesis intricate carbohydrate derivatives has revolutionized domains chemical biology and synthetic chemistry. This review examines function chemistry, namely copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), effectively altering structures producing practical glycoconjugates. Carbohydrates are essential several biological functions, such as cellular recognition immunological responses, however, their complicated structure makes production difficult. Click provides an optimal answer to these issues due its simplicity, high yields bioorthogonality. methodology been extensively used advancement glycoproteins, glycodendrimers glycopeptides, which play a crucial role fields drug discovery, vaccine development diagnostics. In addition, facilitated biodegradable polymers glycomacromolecules that have potential be materials science, for sustainable smart technology. flexibility accuracy CuAAC carbohydrate-based new opportunities investigation, stimulating advancements both biomedicine industrial applications. evaluation also emphasizes capacity expedite multifunctional therapeutic drugs target ailments like cancer.

Язык: Английский

Процитировано

0