Vitamin C in Allergy Mechanisms and for Managing Allergic Diseases: A Narrative Review DOI Creative Commons
Chiara Trincianti, Matteo Naso, Maria Angela Tosca

и другие.

Children, Год журнала: 2025, Номер 12(6), С. 718 - 718

Опубликована: Май 30, 2025

Allergic diseases share a type 2 immune reaction and elevated oxidative stress, contributing to disease pathogenesis exacerbations. Vitamin C (ascorbic acid), fundamental exogenous antioxidant, has been hypothesized attenuate these pathological mechanisms. This narrative review critically examined the most recent evidence concerning role of vitamin in preventing managing allergic diseases, including asthma, rhinitis, atopic dermatitis. consisted three steps: conducting search, reviewing abstracts full texts, discussing results. For this reason, we consulted PubMed database detect pertinence studies according review’s conduct. The final search ended March 2025 included English-language-based international articles, online reports, electronic books. keywords “vitamin disease” system” were used. After complete read ensure that they concerned topic interest. Recent suggests protective for with several reporting reduced stress markers, improved lung function, decreased airway inflammation following regular intake or supplementation. Higher dietary correlates lower asthma prevalence severity, particularly pediatric populations. Conversely, findings regarding rhinitis dermatitis are heterogeneous. While topical ascorbic acid derivatives show promise models, oral does not appear affect risk significantly. demonstrates potential as an add-on therapy management by attenuating respiratory inflammation. However, its remains less clear. Further multicentric, well-designed clinical trials necessary establish definitive guidelines supplementation management.

Язык: Английский

Vitamin C in Allergy Mechanisms and for Managing Allergic Diseases: A Narrative Review DOI Creative Commons
Chiara Trincianti, Matteo Naso, Maria Angela Tosca

и другие.

Children, Год журнала: 2025, Номер 12(6), С. 718 - 718

Опубликована: Май 30, 2025

Allergic diseases share a type 2 immune reaction and elevated oxidative stress, contributing to disease pathogenesis exacerbations. Vitamin C (ascorbic acid), fundamental exogenous antioxidant, has been hypothesized attenuate these pathological mechanisms. This narrative review critically examined the most recent evidence concerning role of vitamin in preventing managing allergic diseases, including asthma, rhinitis, atopic dermatitis. consisted three steps: conducting search, reviewing abstracts full texts, discussing results. For this reason, we consulted PubMed database detect pertinence studies according review’s conduct. The final search ended March 2025 included English-language-based international articles, online reports, electronic books. keywords “vitamin disease” system” were used. After complete read ensure that they concerned topic interest. Recent suggests protective for with several reporting reduced stress markers, improved lung function, decreased airway inflammation following regular intake or supplementation. Higher dietary correlates lower asthma prevalence severity, particularly pediatric populations. Conversely, findings regarding rhinitis dermatitis are heterogeneous. While topical ascorbic acid derivatives show promise models, oral does not appear affect risk significantly. demonstrates potential as an add-on therapy management by attenuating respiratory inflammation. However, its remains less clear. Further multicentric, well-designed clinical trials necessary establish definitive guidelines supplementation management.

Язык: Английский

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