Lichen Planus: A Cross-Sectional Evaluation of US Dermatologists’ Comorbidity Screening and Management Patterns

Dermatology and Therapy, Год журнала: 2025, Номер unknown

Опубликована: Апрель 24, 2025

Язык: Английский

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Characteristics, comorbidities, and treatment practices of lichen planus in Northern Finland: A register‐based study among 619 subjects

Health Science Reports, Год журнала: 2023, Номер 6(6)

Опубликована: Июнь 1, 2023

Lichen planus (LP) is a common itching skin disease where lesions appear on the and mucous membranes. However, epidemiology of LP not yet sufficiently understood. The aim this study was to retrospectively map out characteristics, comorbidities treatments patients diagnosed with LP.

Язык: Английский

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Crossroads between Skin and Endocrine Glands: The Interplay of Lichen Planus with Thyroid Anomalies

Biomedicines, Год журнала: 2023, Номер 12(1), С. 77 - 77

Опубликована: Дек. 28, 2023

In this narrative review, we aimed to overview the interplay between lichen planus (LP) and thyroid conditions (TCs) from a dual perspective (dermatologic endocrine), since current gap in understanding LP-TC connections is found so far topic still matter of debate. We searched PubMed Inception October 2023 by using key terms “lichen planus” “thyroid”, (alternatively, “endocrine” or “hormone”). included original clinical studies humans according three sections: LP TC dysfunction, autoimmunity, neoplasia. Six confirmed an association dysfunction (exclusively hypothyroidism) LP/OL (oral LP); note, only one study addressed cutaneous LP. The sample size LP/OLP groups varied 12–14 1500 individuals. Hypothyroidism prevalence OLP was 30–50%. A higher rate levothyroxine replacement identified among patients, at 10% versus 2.5% controls. highest OR (odd ratio) treated hypothyroidism amid 2.99 (p < 0.005). be associated with milder phenotype two studies. single cohort revealed similar non-LP. Non-confirmatory (only on OLP, not LP) five cohorts: controls, showed that subjects actually had lower controls (1% 4%). Positive autoimmunity eight studies; cohorts varied, for instance, 619 persons 76, 92, 105, 108, 192, 247, 585 patients (a total 1405) respectively; notably, largest control group 10,441 Four clusters approaches respect were found: analysis HT/ATD (Hashimoto’s thyroiditis/autoimmune diseases) prevalence; considerations over specific antibody levels; sex-related features females are more prone autoimmunity; associations (if any) aspects LP/OLP. HT statistically significantly higher, as follows: 19% 5%; 12% 6%; 20% 9.8%. addressing ATDs. One did confirm correlation OLP-associated elements (and severity) values against thyroid, another positive TPOAb (anti-thyroperoxidase antibodies) often erosive than non-erosive (68% 33%). Just reverse, (9% 15%). Five case-control issue prior diagnosed (no identified); them treatment (at 8.9%, 9.7%, 10.6%) conclusion, regard LP/OLP-TC, note several main practical points multidisciplinary practitioners: rather requires awareness; when it comes type mostly, should expected; female ATDs; potential ratio taking found, thus good collaboration endocrinology team mandatory; far, individuals have been risk nodules/cancer.

Язык: Английский

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Lichen planus—the role of age and gender in clinical appearance and treatment

Wiener Medizinische Wochenschrift, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 12, 2024

Язык: Английский

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