Toxicological and genotoxicological assessment of water extracts of sewage sludge and other biogenic wastes: A piece of the SLURP jigsaw puzzle
Chemosphere,
Год журнала:
2025,
Номер
374, С. 144175 - 144175
Опубликована: Фев. 20, 2025
Given
the
considerable
quantities
of
biogenic
matrices
employed
in
agricultural
applications,
there
is
growing
concern
about
potential
negative
effects
resulting
from
presence
harmful
contaminants.
The
project
"SLURP
-
SLUdge
Recovery
Agriculture:
Environment
and
Health
Protection"
planned
a
multi-stage
approach
which
application
wide
battery
bioassays
was
proposed
as
an
effective
tool
to
measure
direct
interaction
with
different
components
ecosystem,
molecular
whole
organism
level.
aim
present
study,
part
"SLURP"
project,
characterise
toxicological
genotoxicological
properties
water
extracts
wastes
using
several
assays
based
on
plant,
bacterial
human
cells.
aqueous
four
sewage
sludges,
liming
material,
two
manure
slurries
swine
bovine
origin,
digestate
compost
were
chemically
characterised
for
inorganic
ions
heavy
metals.
Then
analysed
tests
A.cepa,
C.sativus,
L.sativum,
S.typhimurium
hepatoma
cell
line
(HepG2)
assess
toxicity
(seed
germination,
root
elongation,
proliferation),
mutagenicity
genotoxicity
(primary
DNA
damage,
chromosomal
aberrations).
exhibited
chemical
heterogeneity.
Ammonia
nitrogen,
Ca2+,
Fe
Zn
most
abundant
elements.
Toxic
caused
A.cepa
L.sativum
by
all
extracts,
while
non-toxic
Genotoxic
instead
almost
at
least
highest
dose
tested,
only
samples
one
sludge,
digestate,
compost,
damage
None
induced
mutagenic
S.typhimurium.
A
comprehensive
interpretation
these
results
can
be
achieved
through
integrated
evaluation
eco-toxicological
data
obtained
throughout
entire
project.
Язык: Английский
Evaluation of Ecotoxicity in Waste Leachate: A Current Status of Bioassay and Chemical Analysis
Toxics,
Год журнала:
2025,
Номер
13(3), С. 198 - 198
Опубликована: Март 10, 2025
As
global
waste
generation
increases,
toxicity
has
become
a
significant
issue.
Among
various
hazardous
properties,
ecotoxicity
refers
to
the
risks
that
may
pose
environment.
It
is
evaluated
through
aquatic
bioassays
assess
effects
of
leaching
contaminants,
as
well
soil
assessments
where
buried.
To
clarify
these
issues,
this
study
collected
methods
from
international
organizations
and
countries
analyzed
case
studies
for
leachates.
The
criteria
determining
leachates
were
also
reviewed,
revealing
inconsistencies
in
across
European
Union,
United
States,
Canada,
Asian
countries.
Additionally,
applied
leachates,
further
contributing
inconsistencies.
Given
variations,
we
recommend
developing
unified
method,
standardized
bioassays,
consistent
assessing
Язык: Английский