THE ROLE OF PHARMACISTS IN PERSONALISED MEDICINE: A REVIEW OF INTEGRATING PHARMACOGENOMICS INTO CLINICAL PRACTICE
Obe Destiny Balogun,
Oluwatoyin Ayo-Farai,
Oluwatosin Ogundairo
и другие.
International Medical Science Research Journal,
Год журнала:
2024,
Номер
4(1), С. 19 - 36
Опубликована: Янв. 8, 2024
This
paper
explores
the
transformative
role
of
pharmacists
in
integrating
pharmacogenomics
into
clinical
practice.
Pharmacogenomics,
study
genetic
influences
on
drug
response,
presents
an
unprecedented
opportunity
to
personalise
medication
management.
The
pharmacist's
has
evolved
from
dispensing
becoming
crucial
interpreting
and
applying
genomic
data
for
optimised
therapeutic
outcomes.
We
delve
foundations
pharmacogenomics,
historical
milestones,
its
applications
responsibilities
include
data,
collaborating
with
healthcare
providers,
counselling
patients,
Medication
Therapy
Management.
Challenges,
such
as
ethical
considerations
legal
frameworks,
are
navigated
ensure
responsible
Education
emerges
a
cornerstone,
recommendations
enhance
literacy
through
comprehensive
educational
programs.
Ethical
highlight
importance
informed
consent,
privacy
safeguards,
equitable
access
pharmacogenomic
information.
future
pharmacy
practice
relies
interdisciplinary
collaboration,
continuous
education,
adherence,
positioning
integral
contributors
personalised
medicine
landscape.
Keywords:
Personalised
Medicine,
Pharmacy
Practice,
Genomic
Literacy,
Interdisciplinary
Collaboration.
Язык: Английский
Integrating pharmacogenomic testing into personalized medicine practices in the USA: Implications for medication quality control and therapeutic efficacy
James Tabat Bature,
Michael Alurame Eruaga,
Esther Oleiye Itua
и другие.
GSC Biological and Pharmaceutical Sciences,
Год журнала:
2024,
Номер
26(3), С. 019 - 026
Опубликована: Март 9, 2024
This
concept
paper
explores
the
integration
of
pharmacogenomic
testing
into
personalized
medicine
practices
in
USA
and
its
implications
for
medication
quality
control
therapeutic
efficacy.
By
leveraging
genetic
information
to
optimize
selection
dosing,
this
aims
improve
patient
outcomes
minimize
adverse
drug
reactions,
thereby
enhancing
safety
efficacy
clinical
practice.
Integrating
has
potential
revolutionize
healthcare
by
improving
USA.
The
begins
discussing
current
landscape
role
optimizing
dosing.
It
then
examines
benefits
integrating
practice,
including
improved
safety,
efficacy,
cost-effectiveness.
Key
considerations
implementing
are
discussed,
regulatory
considerations,
reimbursement
challenges,
ethical
considerations.
also
highlights
importance
provider
education
engagement
successful
implementation
testing.
Through
a
comprehensive
analysis,
provide
insights
testing,
providers
can
personalize
leading
patients.
Язык: Английский
A call to action for ambulatory care pharmacists for the treatment of depression and anxiety in primary care: An opinion paper of the ambulatory care and central nervous system practice research networks of the American College of Clinical Pharmacy
JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
Abstract
The
need
for
mental
health
care
has
increased
in
recent
years,
especially
due
to
the
coronavirus
disease
2019
pandemic.
Simultaneously,
supply
of
clinicians
declined
alongside
decreases
primary
clinicians.
As
management
depression
and
anxiety
increasingly
moved
care,
ambulatory
pharmacists
must
be
equipped
with
knowledge
skills
needed
patients
these
illnesses.
objective
this
collaborative
Opinion
Paper
Ambulatory
Care
Central
Nervous
System
Practice
Research
Networks
is
provide
practical
guidance
on
role
educational
needs
within
settings
serve
as
a
call
action.
authors
performed
narrative
review
PubMed
database
from
January
1,
1990
November
10,
2024
using
search
terms
pertaining
care.
reference
lists
articles
were
then
reviewed
additional
references.
can
help
meet
Their
evidence‐based
medicine,
drug
interactions,
adverse
effects,
other
areas
pharmaceutical
coupled
their
training
interprofessional
team‐based
make
them
an
ideal
addition
team
anxiety.
A
variety
programs
are
available
augment
skills.
Similarly,
at
all
levels,
student
resident,
should
incorporate
experiences
prepare
future
address
patients.
leverage
they
possess
fill
gap
living
settings.
Язык: Английский
Understanding Adverse Drug Effects and The Clinical Pharmacist's Role in Their Management
Journal of Natural Science Review,
Год журнала:
2024,
Номер
2(4), С. 1 - 35
Опубликована: Дек. 30, 2024
Pharmacological
interventions
are
the
cornerstone
of
modern
medical
treatment,
designed
to
address
specific
diseases,
alleviate
symptoms,
and
improve
patients'
quality
life.
However,
misconceptions
persist
regarding
drug
effects,
such
as
belief
that
all
pharmacological
effects
beneficial
side
adverse.
Clinical
Pharmacists
(CPs)
play
a
crucial
role
in
managing
drug-related
problems,
but
their
contributions
remain
underrecognized
Afghanistan.
This
study
aims
these
emphasize
CPs
adverse
(ADEs).
A
comprehensive
literature
review
was
conducted
explore
categorization
ADE
management.
The
findings
reveal
not
always
intended
vital
identifying
risk
factors
polypharmacy
characteristics,
establishing
therapeutic
goals,
mitigating
ADEs.
In
conclusion,
ineffectiveness
lack
efficacy
should
be
categorized
ADEs,
contribute
outcomes
deemed
Integrating
more
effectively
into
healthcare
systems
is
essential
optimize
medication
management,
ensure
safer
treatments,
enhance
patient
outcomes.
Язык: Английский
Clinical Utility and Implementation of Pharmacogenomics for the Personalisation of Antipsychotic Treatments
Pharmaceutics,
Год журнала:
2024,
Номер
16(2), С. 244 - 244
Опубликована: Фев. 7, 2024
Decades
of
pharmacogenetic
research
have
revealed
genetic
biomarkers
clinical
response
to
antipsychotics.
Genetic
variants
in
antipsychotic
targets,
dopamine
and
serotonin
receptors
particular,
metabolic
enzymes
been
associated
with
the
efficacy
toxicity
treatments.
However,
prediction
based
on
these
is
far
from
accurate.
Despite
validity
findings,
utility
remains
unclear.
Nevertheless,
information
CYP
responsible
for
biotransformation
most
commercially
available
antipsychotics
has
proven
be
effective
personalisation
dosing,
resulting
a
reduction
induced
side
effects
an
increase
efficacy.
rarely
used
psychiatric
settings
as
prescription
aid.
Lack
studies
cost-effectiveness,
absence
guidelines
several
commonly
antipsychotics,
cost
testing
delay
results
delivery
hamper
implementation
interventions
settings.
This
narrative
review
will
comment
existing
information,
their
current
future
implementations.
Язык: Английский
The role of pharmacogenomics in personalized medicine: A focus on drug metabolism
Ali Nasser Alsuwaileh,
Ibrahim A. Ibrahim,
Hammad Abdullah Aljaloud
и другие.
International Journal of Health Sciences,
Год журнала:
2024,
Номер
8(S1), С. 1844 - 1859
Опубликована: Янв. 15, 2024
Background:
The
conventional
model
of
drug
treatment
may
involve
set
protocols
use
and
not
the
currently
variegated
pharmacology
patterns
due
to
mutations
in
metabolism
enzymes.
But
recent
innovations
pharmacogenomics
have
provided
new
insight
on
feeds
processing
drugs
through
genetic
environment
components
that
present
a
more
divergent
view
treatment.
Aim:
purpose
this
study
is
understand
specificity
framework
individualized
medicine
its
potential
enhance
efficacy
safety
lifestyle
differences.
Methods:
A
literature
search
was
performed
compare
effects
variations
as
metabolism.
research
also
focuses
at
how
testing
used
developing
custom
therapies.
Results:
major
impact
rate
along
with
their
effectiveness
toxicity.
Of
course,
assessing
health-promoting
behaviours
include
diet
physical
activity,
or
lack
thereof,
well
others,
can
strongly
therapeutic
success.
Conclusion:
Potential
for
manufactured
Meal
ability
highlight
vests
are
crucial
finding
personalized
treatments.
Язык: Английский