Advances in exosomes utilization for clinical applications in cancer
Trends in cancer,
Год журнала:
2024,
Номер
10(10), С. 947 - 968
Опубликована: Авг. 20, 2024
Язык: Английский
Recent Exploration of Solid Cancer Biomarkers Hidden Within Urine or Blood Exosomes That Provide Fundamental Information for Future Cancer Diagnostics
Diagnostics,
Год журнала:
2025,
Номер
15(5), С. 628 - 628
Опубликована: Март 5, 2025
Cancer
cells
exhibit
abnormal
behavior
compared
to
normal
cells.
They
ignore
growth
arrest
signals
such
as
contact
inhibition,
a
mechanism
that
stops
their
proliferation
when
they
collide
with
surrounding
cells,
and
proliferate
in
an
uncontrolled
manner,
destroying
tissue.
Early
detection
treatment
of
cancer
are
therefore
important
for
healthy
longevity.
differ
from
characteristic
gene
expression
due
abnormalities.
markers
reflect
these
characteristics
have
been
searched
applied
diagnosis.
Although
analysis
blood
antigens
has
the
main
method,
further
development
diagnostic
system
is
needed
early
cancer.
Next-generation
sequencers
improved
technology,
making
it
possible
analyze
detailed
nucleic
acid
molecules
or
urine.
In
addition,
release
extracellular
vesicles,
exosomes,
which
known
contain
may
serve
markers.
This
review
summarizes
latest
findings
on
exosomal
Язык: Английский
The diagnostic accuracy of urine-derived exosomes for bladder cancer: a systematic review and meta-analysis
World Journal of Surgical Oncology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Окт. 29, 2024
Язык: Английский
Recent Electrochemical Advancements for Liquid-Biopsy Nucleic Acid Detection for Point-of-Care Prostate Cancer Diagnostics and Prognostics
Biosensors,
Год журнала:
2024,
Номер
14(9), С. 443 - 443
Опубликована: Сен. 14, 2024
Current
diagnostic
and
prognostic
tests
for
prostate
cancer
require
specialised
laboratories
have
low
specificity
detection.
As
such,
recent
advancements
in
electrochemical
devices
point
of
care
(PoC)
detection
seen
significant
interest.
Liquid-biopsy
relevant
circulating
exosomal
nucleic
acid
markers
presents
the
potential
minimally
invasive
testing.
In
combination,
DNA
RNA
present
an
innovative
approach
novel
diagnostics,
potentially
directly
within
clinic.
Recent
research
impedance
spectroscopy,
voltammetry,
chronoamperometry
potentiometric
sensing
using
field-effect
transistors
will
be
discussed.
Evaluation
PoC
relevance
these
techniques
their
fulfilment
WHO’s
REASSURED
criteria
medical
diagnostics
is
described.
Further
areas
exploration
testing
progression
to
clinical
implementation
are
assessed.
Язык: Английский
Urinary miRNAs in bladder cancer
Clinica Chimica Acta,
Год журнала:
2024,
Номер
unknown, С. 120113 - 120113
Опубликована: Дек. 1, 2024
Язык: Английский
Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer
International review of cell and molecular biology,
Год журнала:
2024,
Номер
unknown, С. 135 - 197
Опубликована: Сен. 12, 2024
Язык: Английский
Non-coding RNAs in bladder cancer, a bridge between gut microbiota and host?
Frontiers in Immunology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 19, 2024
In
recent
years,
the
role
of
gut
microbiota
(GM)
in
bladder
cancer
has
attracted
significant
attention.
Research
indicates
that
GM
not
only
contributes
to
carcinogenesis
but
also
influences
efficacy
adjuvant
therapies
for
cancer.
Despite
this,
interventions
targeting
have
been
widely
employed
prevention
and
treatment
cancer,
mainly
due
incomplete
understanding
complex
interactions
between
host
flora.
Simultaneously,
aberrantly
expressed
non-coding
RNAs
(ncRNAs)
frequently
associated
with
playing
crucial
roles
processes
such
as
cell
proliferation,
invasion,
drug
resistance.
It
is
known
regulation
GM-mediated
pathophysiological
partly
regulated
through
epigenetic
pathways.
At
same
time,
ncRNAs
are
increasingly
regarded
signaling
molecules
involved
regulation.
Accordingly,
this
review
analyzes
closely
related
context
occurrence
treatment,
summarizes
their
interaction
cancer-related
phenotypes.
The
aim
delineate
a
regulatory
network
provide
new
perspective
study
Язык: Английский