Polyglycerol‐Grafted Graphene Oxide with pH‐Responsive Charge‐Convertible Surface to Dynamically Control the Nanobiointeractions for Enhanced in Vivo Tumor Internalization
Small,
Год журнала:
2025,
Номер
unknown
Опубликована: Июнь 1, 2025
Abstract
pH‐responsive
charge‐convertible
nanomaterials
(NMs)
ameliorate
the
treatment
of
cancer
via
simultaneously
reducing
nonspecific
interactions
during
systemic
circulation
and
improving
targeted
uptake
within
solid
tumors.
While
promising,
little
is
known
about
how
pH‐responsiveness
NMs
directs
their
with
biological
systems,
leading
to
compromised
performance,
including
off‐target
retention
low
specificity
tumor
cells.
In
present
study,
polyglycerol‐grafted
graphene
oxide
bearing
amino
groups
(GOPGNH
2
)
at
different
densities
are
reacted
dimethylmaleic
anhydride
(DMMA),
a
moiety,
generate
set
GOPGNH‐DMMA
variants.
This
permits
assessment
quantitative
correlation
between
structure
pH‐responsiveness,
dynamic
proteins
cells,
as
well
in
vivo
fate.
Through
systematic
investigation,
it
revealed
that
GOPGNH115‐DMMA
prepared
from
GOPGNH
higher
amine
density
experienced
fast
charge
conversion
pH
7.4
induce
non‐specific
early
stages,
whereas
GOPGNH60‐DMMA
GOPGNH30‐DMMA
lower
retarded
enhance
accumulation.
Notably,
also
associated
enough
amounts
under
acidic
conditions
promote
internalization.
The
findings
will
inform
design
for
enhanced
accuracy
efficacy.
Язык: Английский
Smart chitosan Schiff base ferrite: a dual-action visible light photocatalyst for dye degradation and antimicrobial defense
Musaib Y. Wani,
Shakeel A. Shah
New Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
This
study
presents
the
synthesis
and
applications
of
visible-light
photocatalyst
for
environmental
remediation.
Язык: Английский
A catfish Skin-inspired dual-antifouling epoxy thermoset as coatings for marine antifouling applications
Chemical Engineering Journal,
Год журнала:
2024,
Номер
unknown, С. 159057 - 159057
Опубликована: Дек. 1, 2024
Язык: Английский
Eco‐Friendly, Recyclable Supramolecular Inks Incorporating Multi‐Walled Carbon Nanotubes
Chunxiao Ding,
Meng Bai,
Ruirui Liu
и другие.
Macromolecular Chemistry and Physics,
Год журнала:
2024,
Номер
225(21)
Опубликована: Авг. 26, 2024
Abstract
In
contemporary
society,
with
its
emphasis
on
environmental
stewardship,
the
development
of
“green”
(eco‐friendly)
inks
is
paramount
importance.
These
are
utilized
across
a
broad
spectrum
applications,
ranging
from
printing
packaging
material
to
3D
functional
components.
This
study
explores
synthesis
eco‐friendly,
biodegradable
supramolecular
polymer
materials
predicated
ureido‐pyrimidinone
(UPy).
The
subsequent
formulation
these
into
achieved
by
incorporation
multi‐walled
carbon
nanotubes
(MWCNTs).
resultant
exhibit
outstanding
photothermal
conversion
properties,
robust
electrical
conductivity,
intrinsic
self‐repair
capabilities,
and
superior
writability.
Moreover,
this
research
demonstrates
recyclability
MWCNTs
within
ink
matrix,
exhibiting
recovery
efficiency
≈90%.
Such
high
rate
offers
novel
perspective
sustainable
reuse
conductive
fillers
in
polymer‐based
inks.
Язык: Английский