
Macromolecular Rapid Communications, Год журнала: 2024, Номер 45(22)
Опубликована: Авг. 6, 2024
Abstract Digitally‐encoded poly(phosphodiesters) ( d ‐PPDE) with highly complex primary structures are evaluated for layer‐by‐layer (LbL) assembly. To be easily decoded by mass spectrometry (MS), these digital polymers contain many different monomers: 2 coding units allowing binary encryption, 1 cleavable spacer controlled MS fragmentation, and 3 tags fragment identification. These heteropolymers therefore composed of 6 motifs. Despite this strong sequence heterogeneity, it is found that they enable a LbL film formation. For instance, regular growth observed when alternating the deposition negatively‐charged ‐PPDE positively‐charged poly(allyl amine hydrochloride) (PAH). Yet, in approach, interdistance between consecutive coded layers remains relatively small, which may an issue data storage applications, especially selective decoding stored information. Using poly(sodium 4‐styrene sulfonate) (PSS) as intermediate non‐coded polyanion, shown can achieved, while still maintaining growth. Last but not least, work small molecular weight (i.e., significantly smaller than those PAH PSS) enables
Язык: Английский