Nanofiber Drug Delivery Systems: Recent Advances in Nanofabrication and Their Role in Targeted Therapy in Cancer, Neurodegenerative, and Cardiovascular Diseases DOI

Satyam Yadav,

Amit Sharma, Balak Das Kurmi

и другие.

Polymers for Advanced Technologies, Год журнала: 2025, Номер 36(5)

Опубликована: Май 1, 2025

ABSTRACT Nanofiber‐based drug delivery systems show strong potential due to their high surface area‐to‐volume ratio and adjustable structure. Recent studies demonstrated loading efficiencies exceeding 85%, with sustained release kinetics up 96 h. In cancer models, nanofiber‐based carriers improved accumulation at tumor sites by 3–4 fold compared conventional formulations, enhancing therapeutic efficacy minimizing systemic toxicity. This review outlines methods for precise nanofiber shape function control through electrospinning solution blow spinning techniques. advancements in technology have proven promising biomedical applications where they are utilized tissue engineering, neurodegenerative disease management, wound healing, targeted therapy. Nanofibers as an optimal system that improves cellular restoration, together controlled deep penetration capabilities. The recent development of dual‐drug systems, stimuli‐responsive nanofibers, scaffolds composed nanofibers smart materials has expanded usage precision medicine. Research now demonstrates facilitate remodeling functions along angiogenesis promotion, inflammatory response stability improvement. also focuses on the patents a system. addition, this presents new approaches overcome these challenges based interdisciplinary cooperation, AI‐driven design such sophisticated bioinformatics tools. review, advances prospects realizing revolution field improving healthcare outcomes presented detailed overview.

Язык: Английский

Polymeric Nanofibers via Green Electrospinning for Safe Food Engineering DOI Open Access

Weiqiang Wang,

Xingjian Yang, Hongyi Yin

и другие.

Macromolecular Rapid Communications, Год журнала: 2025, Номер unknown

Опубликована: Фев. 22, 2025

Abstract Electrospun functional nanofibers enable controlled release of the loaded active ingredient and an adjustable dissolution rate. However, widespread use toxic organic solvents in electrospinning poses risks to human health environment whereas increasing production costs complexity. This article examines application eco‐friendly technologies food engineering, with a focus on water‐based melt methods. It provides detailed analysis water‐soluble biopolymers synthetic polymers, highlighting their current applications challenges engineering. Water‐based is proposed as sustainable alternative, offering scalability reduced environmental impact. transition essential for advancing engineering toward more environmentally responsible practices.

Язык: Английский

Процитировано

3

Sustainable Electrospun Hybrid Nanofibers for Triboelectric Nanogenerators DOI Creative Commons

Sweetly Thomas‐Kochakkadan,

Marcos Duque, Gonzalo Murillo

и другие.

Small, Год журнала: 2025, Номер unknown

Опубликована: Янв. 29, 2025

Abstract Triboelectric nanogenerators (TENGs) have emerged as potential energy‐harvesting modules for miniaturized devices. TENG are derived often from components having low sustainability whereas the current environmental and economic circumstances demand a focus on sustainable, ecologically friendly approaches development of advanced hybrid materials. Herein, recycled polyethylene terephthalate (PET) along with commercially available nylon electrospun into nanofibers The obtained characterized using microscopy, spectroscopy, thermal mechanical analysis. Electrospinning pristine titanium dioxide nanoparticles (TiO 2 NPs) blended polymer solutions resulted in uniform without beads. addition TiO NPs improved properties significantly stability nanofibers. performance fabricated device has been by functionalizing NPs. Particularly, combination PET (5%) functionalized reached peak power density 23.44 mW m − surface charge 6.81 µC , max output voltage 111 V −1.61µA. This study opens new avenue to utilize upcycled cost‐effective polymers processed electrospinning powerful tool fabrication next generation sustainable

Язык: Английский

Процитировано

0

Advancements in nanotechnology for biomedical and wearable applications DOI
Nagender Singh, Amandeep Kaur, Amit Madhu

и другие.

Next Materials, Год журнала: 2025, Номер 8, С. 100658 - 100658

Опубликована: Апрель 18, 2025

Язык: Английский

Процитировано

0

Nanofiber Drug Delivery Systems: Recent Advances in Nanofabrication and Their Role in Targeted Therapy in Cancer, Neurodegenerative, and Cardiovascular Diseases DOI

Satyam Yadav,

Amit Sharma, Balak Das Kurmi

и другие.

Polymers for Advanced Technologies, Год журнала: 2025, Номер 36(5)

Опубликована: Май 1, 2025

ABSTRACT Nanofiber‐based drug delivery systems show strong potential due to their high surface area‐to‐volume ratio and adjustable structure. Recent studies demonstrated loading efficiencies exceeding 85%, with sustained release kinetics up 96 h. In cancer models, nanofiber‐based carriers improved accumulation at tumor sites by 3–4 fold compared conventional formulations, enhancing therapeutic efficacy minimizing systemic toxicity. This review outlines methods for precise nanofiber shape function control through electrospinning solution blow spinning techniques. advancements in technology have proven promising biomedical applications where they are utilized tissue engineering, neurodegenerative disease management, wound healing, targeted therapy. Nanofibers as an optimal system that improves cellular restoration, together controlled deep penetration capabilities. The recent development of dual‐drug systems, stimuli‐responsive nanofibers, scaffolds composed nanofibers smart materials has expanded usage precision medicine. Research now demonstrates facilitate remodeling functions along angiogenesis promotion, inflammatory response stability improvement. also focuses on the patents a system. addition, this presents new approaches overcome these challenges based interdisciplinary cooperation, AI‐driven design such sophisticated bioinformatics tools. review, advances prospects realizing revolution field improving healthcare outcomes presented detailed overview.

Язык: Английский

Процитировано

0