Dysregulated Signaling Pathways in Canine Mammary Tumor and Human Triple Negative Breast Cancer: Advances and Potential Therapeutic Targets DOI Open Access
Chen Mei,

Ying Liu,

Zhenyi Liu

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 26(1), С. 145 - 145

Опубликована: Дек. 27, 2024

In 2022, human breast cancer (HBC) and canine mammary tumors (CMTs) remained the most prevalent malignant worldwide, with high recurrence lethality rates, posing a significant threat to dog health. The development of involves multiple signaling pathways, highlighting need for effective inhibitory drugs that target key proteins in these pathways. This article reviews dysregulation EGFR, PI3K/AKT/mTOR, Hippo, pyroptosis, PD-1/PD-L1 pathways HBC CMT, as well corresponding used inhibit tumor growth, aim providing theoretical support more efficient drugs.

Язык: Английский

Combining photodynamic therapy and ATM inhibition using modified bovine serum albumin: A co-delivery nano platform for eliciting pyroptosis and apoptosis to fuel TNBC therapy DOI

Yuao Feng,

Zeliang Wu,

Hui Liu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142140 - 142140

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Dying to survive: harnessing inflammatory cell death for better immunotherapy DOI
Long Cheng, Yibo Wang, Ying Zhang

и другие.

Trends in cancer, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Dysregulated Signaling Pathways in Canine Mammary Tumor and Human Triple Negative Breast Cancer: Advances and Potential Therapeutic Targets DOI Open Access
Chen Mei,

Ying Liu,

Zhenyi Liu

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 26(1), С. 145 - 145

Опубликована: Дек. 27, 2024

In 2022, human breast cancer (HBC) and canine mammary tumors (CMTs) remained the most prevalent malignant worldwide, with high recurrence lethality rates, posing a significant threat to dog health. The development of involves multiple signaling pathways, highlighting need for effective inhibitory drugs that target key proteins in these pathways. This article reviews dysregulation EGFR, PI3K/AKT/mTOR, Hippo, pyroptosis, PD-1/PD-L1 pathways HBC CMT, as well corresponding used inhibit tumor growth, aim providing theoretical support more efficient drugs.

Язык: Английский

Процитировано

2