American Journal of Neuroradiology,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 9, 2024
Precise
and
individualized
targeting
of
the
ventral
intermediate
thalamic
nucleus
for
MR-guided
focused
ultrasound
is
crucial
enhancing
treatment
efficacy
avoiding
undesirable
side
effects.
In
this
study,
we
tested
hypothesis
that
spatial
relationships
between
Thalamus
Optimized
Multi
Atlas
Segmentation
derived
segmentations
post-focused
lesion
can
predict
post-operative
effects
in
patients
treated
with
ultrasound.
Movement Disorders,
Год журнала:
2024,
Номер
39(2), С. 453 - 454
Опубликована: Фев. 1, 2024
The
data
that
support
the
findings
of
this
study
are
available
on
request
from
corresponding
author.
not
publicly
due
to
privacy
or
ethical
restrictions.
Frontiers in Neurology,
Год журнала:
2024,
Номер
15
Опубликована: Фев. 26, 2024
MRI-guided
focused
ultrasound
(MRgFUS)
lesioning
is
an
innovative,
safe
and
effective
treatment
which
provides
innovative
development
in
the
field
of
minimally
invasive
stereotactic
neurosurgery.
Based
on
application
energy
under
full
MR
planning
thermal
imaging
control,
unilateral
thalamus,
subthalamic
nucleus,
globus
pallidus
indicated
for
movement
disorders,
including
essential
tremor,
Parkinson’s
disease,
dystonia.
We
started
to
apply
this
technique
February
2019
patients
with
disorders.
The
authors
developed
a
diagnostic
therapeutic
care
pathway,
herewith
proposed
applied
as
explication
standard
clinical
practice
use.
project
was
result
different
methods
such
Health
Technology
Assessment
(HTA),
Strengths,
Weaknesses,
Opportunities
Threats
analysis
(SWOT)
Demin
-Plan,
Do,
Check,
Act
(PDCA)
cycle.
aim
standardize
MRgFUS
diagnostic-therapeutic
pathway
(DTP),
describe
its
appropriateness
phases
(patient
selection,
intervention
phase
follow-up).
Here,
we
described
detail
our
experience
DTP
from
up
now
610
Stereotactic and Functional Neurosurgery,
Год журнала:
2024,
Номер
102(4), С. 203 - 208
Опубликована: Янв. 1, 2024
<b><i>Introduction:</i></b>
Magnetic
resonance
guided
focused
ultrasound
(MRgFUS)
thalamotomy
is
an
effective
treatment
for
drug-resistant
tremor.
The
most
frequent
side
effects
are
ataxia,
gait
disturbance,
paresthesias,
dysgeusia,
and
hemiparesis.
Here,
we
report
the
first
case
of
thalamic
hand
dystonia
rapidly
occurring
after
MRgFUS
ventral
intermediate
nucleus
(V.im).
<b><i>Case
Presentation:</i></b>
was
performed
in
a
60-year-old
left-handed
patient
his
disabling
medically
refractory
essential
intervention
resulted
marked
reduction
action
However,
developed
unvoluntary
abnormal
posture
left
few
days
procedure
with
difficulty
holding
cigarette
between
fingers.
Brain
MRI
revealed
expected
lesion
within
right
V.im
as
well
extension
anteriorly
to
ventro-oralis
nucleus.
Tractography
showed
that
disrupted
dentato-rubro-thalamic
tract
suppressing
also
interrupted
fibers
connecting
superior
frontal
pre-central
cortices
(primary
motor
cortex,
premotor
supplementary
area).
We
hypothesized
interventional
slightly
off
target,
which
induced
dysfunction
cortico-striato-thalamo-cortical
network
cerebello-thalamo-cortical
pathway
reaching
sufficient
threshold
basal
ganglia/cerebellum
circuitry
interference
induce
dystonia.
<b><i>Conclusion:</i></b>
This
rare
effect
emphasizes
risk
imbalance
(i.e.,
ganglia-cerebello-thalamo-cortical
circuit)
secondary
thalamotomy.
American Journal of Neuroradiology,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 9, 2024
Precise
and
individualized
targeting
of
the
ventral
intermediate
thalamic
nucleus
for
MR-guided
focused
ultrasound
is
crucial
enhancing
treatment
efficacy
avoiding
undesirable
side
effects.
In
this
study,
we
tested
hypothesis
that
spatial
relationships
between
Thalamus
Optimized
Multi
Atlas
Segmentation
derived
segmentations
post-focused
lesion
can
predict
post-operative
effects
in
patients
treated
with
ultrasound.
