Oxytocin Increases Negative Cognitive Bias in Females with Eating Disorders DOI Creative Commons
Victoria Burmester, E. Marcia Sheridan, Nikita Julius

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Июль 5, 2023

Abstract Eating disorders typically emerge in adolescence 1 , a critical period for brain development and social change 2 meaning interpersonal difficulties—including interpretation biases—frequently co-occur 3 . Oxytocin is neuropeptide that modulates cognition has been particularly linked to prosocial effects 4 However, date, no study investigated oxytocin’s on negative bias adolescents with eating disorders. Here we show adolescent females anorexia or bulimia nervosa made more interpretations than controls when presented ambiguous scenarios. As predicted, intranasal oxytocin reduced interpretations, but only participants without an disorder. Unexpectedly, increased large effect disorder reaching threshold autism screen. also neutral overall effect. The results of this suggest administration may not benefit girls because it the degree situations these groups compared controls. increase signal populations extant biases, which clinical practice might from addressing.

Язык: Английский

Oxytocin Amplifies Negative Response to Ambiguity in Adolescent Females With and Without Eating Disorders DOI Creative Commons
Victoria Burmester, E. Marcia Sheridan, Nikita Julius

и другие.

European Eating Disorders Review, Год журнала: 2025, Номер unknown

Опубликована: Янв. 30, 2025

ABSTRACT Objective Eating disorders (ED) typically emerge in adolescence, a critical period for brain development and peer bonding. Interpersonal difficulties—particularly social anxiety—frequently co‐occur with ED. Oxytocin is neuropeptide that modulates cognition linked to prosocial effects. To date, no study has investigated oxytocin's effects on negative interpretation bias toward ambiguous information adolescents Methods Forty‐eight female aged 16 17 years without EDs took part placebo‐controlled, double‐blinded, randomised, crossover trial investigating the of 24 IU intranasal oxytocin interpretations scenarios. Participants controls were tested twice, approximately one week apart. Results Contrary hypothesis, increased overall ( p = 0.019, large effect). Adolescent females AN or BN made more than when presented information. There was group effect those who reached did not reach threshold an autism screen. Conclusions This suggests interpret negatively administration amplifies responses ambiguity adolescent females, including controls. Research tools effectively identify these biases would help widen scope ED treatments adolescents.

Язык: Английский

Процитировано

0
The Status and Prospects of Research on Interpretation Bias DOI Creative Commons

Wang Jielin

The Frontiers of Society Science and Technology, Год журнала: 2024, Номер 6(5)

Опубликована: Янв. 1, 2024

Interpretation bias stands as one of the three fundamental concepts within cognitive processing bias, representing final stage in continuum. When individuals encounter information or situations characterized by ambiguity and unclear meanings, some tend to attribute positive interpretations them (positive interpretation bias), while others exhibit tendencies towards assigning neutral negative (negative bias). This paper delineates concept its associated research materials, paradigms, pertinent studies. Future endeavors should devote greater attention elucidating distinctive characteristics internal mechanisms across diverse demographic groups.

Язык: Английский

Процитировано

1
Oxytocin Increases Negative Cognitive Bias in Females with Eating Disorders DOI Creative Commons
Victoria Burmester, E. Marcia Sheridan, Nikita Julius

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Июль 5, 2023

Abstract Eating disorders typically emerge in adolescence 1 , a critical period for brain development and social change 2 meaning interpersonal difficulties—including interpretation biases—frequently co-occur 3 . Oxytocin is neuropeptide that modulates cognition has been particularly linked to prosocial effects 4 However, date, no study investigated oxytocin’s on negative bias adolescents with eating disorders. Here we show adolescent females anorexia or bulimia nervosa made more interpretations than controls when presented ambiguous scenarios. As predicted, intranasal oxytocin reduced interpretations, but only participants without an disorder. Unexpectedly, increased large effect disorder reaching threshold autism screen. also neutral overall effect. The results of this suggest administration may not benefit girls because it the degree situations these groups compared controls. increase signal populations extant biases, which clinical practice might from addressing.

Язык: Английский

Процитировано

0