Cited by New insights into the hepato-protective effects of ferulic acid based on transcriptomic and metabolomic profiling

High-fiber basil seed flour reduces insulin resistance and hepatic steatosis in high-fat diet mice DOI

Camila Farías, Camila Cisternas,

Angie Caicedo

и другие.

npj Science of Food, Год журнала: 2024, Номер 8(1)

Опубликована: Ноя. 8, 2024

The incidence of insulin resistance (IR) and hepatic steatosis is increasing, with dietary fiber playing a protective role against these disorders. Ocimum basilicum L., widely used in food, pharmaceutical, cosmetic industries, but their health-promoting properties remain underexplored. This study evaluated the effects fiber-rich fraction partially defatted basil seeds (BSF) on IR, steatosis, polyunsaturated fatty acid short-chain (SCFA) profiles high-fat diet (HFD)-fed C57BL/6 J male mice. Mice were assigned to four groups fed either control or HFD, supplemented BSF oat flour for 4 weeks. HFD induced proinflammatory state, significant decreased SCFA production. In contrast, supplementation attenuated liver damage, oxidative stress, inflammation, while increasing n-3 acids liver, adipocytes, erythrocytes, enhancing production, suggesting potential therapeutic benefits managing conditions.

Язык: Английский

Процитировано

Anti-inflammatory diet reduces risk of metabolic dysfunction-associated fatty liver disease among US adults: a nationwide survey DOI

Wei Hu,

Ling Luo,

Mingzi Li

и другие.

Scandinavian Journal of Gastroenterology, Год журнала: 2024, Номер unknown, С. 1 - 10

Опубликована: Авг. 31, 2024

Background While dietary intervention was an important public health strategy for the prevention and of metabolic dysfunction-associated fatty liver disease (MAFLD), effect diet-induced inflammation on MAFLD has not been studied in detail. Therefore, we aimed to analyze relationship between inflammatory index (DII) MAFLD.

Язык: Английский

Процитировано

LDT409 (pan-PPAR partial agonist) mitigates metabolic dysfunction-associated steatotic liver disease in high-fructose-fed mice DOI