Clinical Endocrinology,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 11, 2024
ABSTRACT
Background
Paediatric
obesity
is
a
global
public
health
concern.
While
in
most
countries
the
incidence
keeps
rising,
need
for
effective
and
long‐term
management
children
adolescents
living
with
this
chronic,
relapsing
disease
pressing.
Health
behaviour
lifestyle
treatment
(HBLT)
recommended
as
first‐line
treatment.
Methods
Narrative
review.
Results
A
new
generation
of
recently
approved
anti‐obesity
medications
(AOM)
now
has
potential
to
fill
gap
between
limited
effects
on
body
mass
index
(BMI)
by
HBLT
alone
large
metabolic
bariatric
surgery
aged
12
years
older.
While,
semaglutide
phentermine/topiramate,
effectiveness
substantial
relevant,
but
mostly
mild
moderate
adverse
events,
there
evidence
regarding
safety,
outcomes
beyond
BMI
reduction
data
certain
groups
patients,
such
<
minority
groups.
When
integrating
AOM
into
national
healthcare
systems
it
should
be
offered
part
comprehensive
patient‐centred
approach.
Conclusion
This
article
summarizes
recent
developments,
integration
paediatric
management,
identifies
research
gaps.
JAMA Network Open,
Год журнала:
2024,
Номер
7(9), С. e2435425 - e2435425
Опубликована: Сен. 30, 2024
Importance
In
2022,
the
US
House
of
Representatives
passed
a
bipartisan
resolution
(House
Resolution
1118
at
117th
Congress
[2021-2022])
calling
for
meaningful
nutrition
education
medical
trainees.
This
was
prompted
by
increasing
health
care
spending
attributed
to
growing
prevalence
nutrition-related
diseases
and
substantial
federal
funding
via
Medicare
that
supports
graduate
education.
March
2023,
professional
organizations
agreed
identify
competencies
Objective
To
recommend
inclusion
in
improve
patient
population
health.
Evidence
Review
The
research
team
conducted
rapid
literature
review
existing
published
between
July
2013
2023.
Additional
were
identified
from
learning
objectives
selected
nutrition,
culinary
medicine,
teaching
kitchen
curricula;
dietetic
core
competencies;
team–generated
de
novo
competencies.
An
expert
panel
22
subject
matter
experts
15
residency
program
directors
participated
modified
Delphi
process
completed
4
rounds
voting
reach
consensus
on
recommended
competencies,
level
which
they
should
be
included,
recommendations
monitoring
implementation
evaluation
these
Findings
A
total
articles
met
criteria
competency
extraction
yielded
187
Through
gray
other
sources,
researchers
167
additional
354
These
compiled
refined
prior
voting.
After
voting,
36
recommendation:
30
both
undergraduate
levels,
2
only,
only.
Competencies
fell
into
following
themes:
foundational
knowledge,
assessment
diagnosis,
communication
skills,
public
health,
collaborative
support
treatment
specific
conditions,
indications
referral.
panelists
(97%)
assessed
as
part
licensing
board
certification
examinations.
Conclusions
Relevance
represent
US-based
effort
use
establish
students
physician
will
require
an
iterative
institutional
prioritization,
refinement,
current
future
educational
curricula
well
licensure
Diabetes Obesity and Metabolism,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 25, 2025
Abstract
Aims
We
assessed
changes
in
body
composition
following
tirzepatide
treatment
a
substudy
of
participants
with
obesity
or
overweight
from
the
SURMOUNT‐1
trial,
overall
and
post
hoc
clinically
relevant
subgroups.
Materials
Methods
Substudy
(
n
=
160
2539
SURMOUNT‐1)
underwent
dual‐energy
X‐ray
absorptiometry
(DXA)
at
baseline
Week
72.
Body
parameters
were
evaluated
by
analysis
covariance,
logistic
regression
Fisher's
exact
test.
Post
subgroup
analyses
conducted
sex
(female
male),
age
(<50,
50
to
<65,
≥65
years)
total
weight
reduction
tertiles
(≤15.3
kg,
>15.3
≤25.9
>25.9
kg).
Results
The
(pooled
doses
124,
placebo
36)
end
study
DXA
data
73%
female
had
mean
102.5
kg
mass
index
38.0
kg/m
2
.
change
weight,
fat
lean
72
was
−21.3%,
−33.9%
−10.9%
−5.3%,
−8.2%
−2.6%
placebo,
respectively
p
<
0.001
for
all
comparisons).
Of
lost,
approximately
75%
25%
both
placebo.
These
proportions
remained
consistent
across
most
analyses.
Conclusions
In
significantly
reduced
compared
while
analyses,
proportion
lost
as
relatively
including
Nutrition in Clinical Practice,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
Abstract
Incretin
mimetics,
including
glucagon‐like
peptide‐1
and
glucose‐dependent
insulinotropic
polypeptide
agonists,
have
become
first‐line
treatment
options
for
the
of
type
2
diabetes
obesity.
Their
therapeutic
status
is
attributed
to
their
high
level
efficacy
as
well
positive
impact
on
related
comorbidities,
such
sleep
apnea
heart
failure.
Multiple
incretin
mimetics
are
currently
available
with
different
durations
drug
action,
dosing
frequencies,
delivery
devices.
Patients
may
benefit
from
education
proper
administration,
anticipated
adverse
effects,
nutrition
considerations
treatment.
Practitioners
must
monitor
progress
support
patient
achieve
maintenance
doses
optimal
weight
reduction
diabetes‐related
outcomes.
This
review
aims
present
current
literature
supporting
US
Food
Drug
Administration–approved
indications
equip
healthcare
professionals
optimize
care
patients
who
prescribed
these
agents,
provide
insights
into
potential
future
applications,
which
include
dual‐
or
triple‐mechanism
agents
that
injected
administered
orally.
Additional
studies
existing
diabetes,
obesity,
comorbidities
in
a
rapidly
developing
pipeline.
Obesity Pillars,
Год журнала:
2024,
Номер
12, С. 100143 - 100143
Опубликована: Окт. 13, 2024
This
qualitative
study
used
semi-structured
interviews
to
examine
registered
dietitians'
perspectives
on
diet,
nutrition,
and
lifestyle
communication
for
patients
GLP-1
medications
obesity
management.
Nutrients,
Год журнала:
2025,
Номер
17(4), С. 716 - 716
Опубликована: Фев. 18, 2025
Observing
a
patient's
dietary
behaviour
before
bariatric
surgery
may
help
to
predict
their
diet
(and
indirectly,
the
rate
of
weight
loss)
after
procedure.
Consequently,
aim
this
study
was
identify
patterns
(DPs)
in
candidates,
as
well
assess
relationship
between
DPs,
degree
obesity,
and
body
composition.
The
participants
were
comprised
117
candidates.
Data
concerning
diet,
lifestyle,
socioeconomic
status
collected
using
KomPAN®
questionnaire.
following
three
DPs
identified
principal
component
analysis:
'Sandwiches
&
Sweets',
'Fast
Food,
Convenience
Food
Alcohol'
'Prudent'.
Baseline
nutritional
composition
electric
bioimpedance
assessed.
Differences
found
Prudent
DP
primarily
involved
high
consumption
healthy
products.
Following
DP,
differentiated
obesity
most.
In
turn,
Fast
Alcohol
associated
with
higher
likelihood
Degree
III
very
visceral
fat
level
(VFL).
Sandwiches
Sweets
included
most
VFL.
candidates
shown
follow
different
diets,
could
be
identified.
Patients
followed
more
beneficial
which
likely
due
awareness
risks
morbidity
post-surgical
complications.
Socioeconomic
factors
attenuate
association
