Frontiers in Plant Science,
Год журнала:
2022,
Номер
13
Опубликована: Ноя. 29, 2022
Bacterial
fruit
blotch,
caused
by
the
seedborne
gram-negative
bacterium
Acidovorax
citrulli,
is
one
of
most
destructive
bacterial
diseases
cucurbits
(gourds)
worldwide.
Despite
its
prevalence,
effective
and
reliable
means
to
control
blotch
remain
limited.
Transcriptomic
analyses
tissue
culture-based
regeneration
processes
have
revealed
that
organogenesis-associated
cellular
reprogramming
often
associated
with
upregulation
stress-
defense-responsive
genes.
Yet,
there
limited
evidence
supporting
notion
reprogrammed
metabolism
regenerated
tissued
confers
bona
fide
antimicrobial
activity.
Here,
we
explored
anti-bacterial
activity
protocorm-like-bodies
(PLBs)
Phalaenopsis
aphrodite.
Encouragingly,
found
PLB
extract
was
potent
in
slowing
growth
A.
reducing
number
bacteria
attached
watermelon
seeds,
alleviating
disease
symptoms
seedlings
citrulli.
Because
can
be
fractionated
chemically,
predict
during
process
produces
metabolites
antibacterial
In
conclusion,
our
data
demonstrated
developing
PLBs
potential
using
orchid
discover
chemicals
disease.
Cell Biochemistry and Function,
Год журнала:
2023,
Номер
41(3), С. 365 - 374
Опубликована: Март 14, 2023
The
current
study
aimed
to
investigate
the
inhibitory
activity
of
aqueous
extracts
different
plant
parts
Rosa
damascena,
represented
by
whole
rose,
petals,
and
calyces,
against
clinical
isolates
Staphylococcus
spp.,
Escherichia
coli,
Klebsiella
pneumoniae,
inhibition
bacterial
cell.
were
obtained
from
advanced
microbiology
laboratory
for
postgraduate
studies
in
Department
Biology,
Faculty
Education
Girls.
They
isolated
urinary
tract
infections,
which
subsequently
subjected
diagnosis
Vitek-2
compact
system
confirm
type
bacteria
as
well
their
sensitivity
antibiotics.
results
included
aureus,
haemolyticus,
lentus,
saprophyticus,
E.
K.
pneumoniae.
A
test
was
conducted
microbiological
calyces
using
diffusion
method
three
concentrations
each
extract
(25,
50,
100
mg/ml).
showed
ability
all
toward
coli
pneumoniae
not
affected
extract.
concentration
(100
mg/ml)
most
efficient
inhibiting
growth
compared
other
concentrations.
synergistic
effect
antibiotics
examined
(Amoxicillin-clavulanate
10/20
μg,
Piperacillin
Trimethoprim-sulfamethoxazole
23.75/1.25
μg)
investigated
both
it
found
a
action
between
some
towards
two
Resistance
alone.
Bacterial
significant
decrease
rate
adhesion
epithelial
cells
urine
samples
healthy
women
presence
at
with
control
treatment.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION),
Год журнала:
2023,
Номер
51(9), С. 100302 - 100302
Опубликована: Июль 7, 2023
Cordyceps
sinensis
is
a
rare
traditional
Chinese
herbal
material.
The
cultivated
cordyceps
instead
of
the
wild
potential
important
development
trend.
Assessing
consistency
and
very
significant
attention.
method
non-target
screening
mining
quality
markers
in
samples
was
established
by
liquid
chromatography-quadrupole
time-of-flight
high
resolution
mass
spectrometry
(LC-Q-TOF-MS)
combined
with
feature-based
molecular
networking(FBMN)
model
orthogonal
partial
least
square
discriminant
analysis
(OPLS-DA).
Forty-
seven
training
samples,
including
thirty-
three
fourteen
were
firstly
used
to
build
OPLS-DA
original
based
on
6827
feature
m/z
peaks.
1144
peaks
dimensionality
reduction
built
optimized
model,
which
acquired
variable
projected
importance
(VIP)
model.
Twenty
nine
mined
using
S-plot
Moreover,
17
29
identified
FBMN,
eight
markers.
Finally,
an
overall
correct
rate
95.5%
(twenty
two
test
samples)
obtained
for
classification
twenty
It
indicated
that
could
be
FBMN
coupled
OPLS-DA.
Molecules,
Год журнала:
2023,
Номер
28(20), С. 7058 - 7058
Опубликована: Окт. 12, 2023
Phytochemical
investigation
of
the
leaves
Camellia
ptilosperma
S.
Y.
Liang
et
Q.
D.
Chen
led
to
isolation
ten
undescribed
compounds,
including
six
new
triterpenes
(1–6)
and
four
pheophorbide-related
compounds
(7–10).
Meanwhile,
cytotoxic
activity
against
cancer
cell
lines
was
evaluated
by
MTT
assay.
Compound
2
showed
potent
cytotoxicity
toward
HepG2
cells
with
an
IC50
value
2.57
μM.
Compounds
4
5
exhibited
MDA-MB231
cells,
values
11.31
5.52
μM,
respectively.
Additionally,
pheophorbides
these
both
in
presence
absence
light
treatment.
7
exceptional
photocytotoxicity
Hela,
MCF-7,
A549
0.43
0.28
0.92
10
demonstrated
significant
photodynamic
BEL-7402
0.77
μM
0.33
The
antibacterial
7–10
also
tested
for
aureus,
E.
coli,
K.
pneumoniae,
P.
aeruginosa
under
direct
illumination.
8
sensitivity
coli
a
effect,
MIC
0.625
Journal of Experimental Biology and Agricultural Sciences,
Год журнала:
2024,
Номер
12(1), С. 145 - 152
Опубликована: Март 15, 2024
Knema
linifolia
is
widely
used
for
fuel
wood,
fodder
and
healthcare
purposes.
This
plant
treats
various
diseases
in
different
parts
of
India,
including
Assam,
Meghalaya,
Alipurduar
Darjeeling
districts
West
Bengal.
study
was
carried
out
to
determine
the
bactericidal
properties
K.
aqueous
extract.
The
extract
leaves,
bark,
stem
sap
were
tested
against
Escherichia
coli
(gram-negative
bacteria)
&
Staphylococcus
aureus
(gram-positive
bacteria).
Among
extracts,
both
leaf
bark
extracts
found
have
high
potential
can
kill
more
than
60%
bacterial
strains
with
a
concentration
300µg/mL
through
an
agar
diffusion
test.
MIC
(Minimum
Inhibitory
Concentration)
values
recorded
at
≤1000µg/mL
≤500µg/mL,
respectively.
It
has
also
been
that
contain
tannins,
which
might
be
essential
antibacterial
sp.
There
currently
lack
proper
documentation
on
using
linifolia,
makes
it
challenging
conduct
clinical
or
commercial
research
support
new
uses
modern
phototherapy.
aims
fill
this
gap
provide
significant
information
could
lead
changes
medicine.
Natural Product Communications,
Год журнала:
2024,
Номер
19(3)
Опубликована: Март 1, 2024
Objectives
The
current
study
was
conducted
to
evaluate
the
antibacterial
potential
of
leaf
and
fruit
extracts
Zanthoxylum
armatum
against
two
pathogenic
bacterial
isolates,
Staphylococcus
aureus
epidermidis.
Methods
Twelve
commercially
available
antibiotics
were
tested
S.
epidermidis
by
antimicrobial
susceptibility
test
(AST).
Qualitative
analysis
phytochemicals
performed
presence
certain
secondary
metabolites.
activity
Z.
measured
as
a
maximum
zone
inhibition
exhibited
each
extract.
An
in-silico
on
flavonoids
alkaloids
show
their
binding
affinity
with
PBP2a
receptor
protein
TcaR
Results
AST
revealed
that
resistant
Penicillin,
Ampicillin,
Clindamycin,
Vancomycin,
Rifampicin,
Novobiocin,
Oxacillin,
whereas
Streptomycin,
Tetracycline,
Novobiocin.
resulted
in
Saponins,
fixed
oils,
flavonoids,
alkaloids,
starch,
fatty
acids
both
extracts.
produced
methanolic
chloroform
For
epidermidis,
best
benzene
showed
Nitidine
Nevadensin
higher
than
selected
antibiotics,
ie,
Chloramphenicol,
Oxacillin.
interacted
Tambuletin,
followed
Kaempferol.
Conclusion
After
vitro
testing,
silico
advised
extracting
purifying
bioactive
components
from
significant
interaction
virulence
proteins
for
use
natural
antibiotic-resistant
bacteria.
International Journal of Agriculture Environment and Food Sciences,
Год журнала:
2024,
Номер
8(2), С. 261 - 272
Опубликована: Май 2, 2024
This
study
evaluated
the
effects
of
pomegranate
(Punica
granatum
L.)
seed
essential
oil
(PSO)
on
chitosan-based
films.
The
results
showed
that
addition
PSO
slightly
increased
thickness,
while
significantly
decreasing
moisture
content,
and
solubility
properties.
color
values
composite
films
containing
changed
noticeably,
with
a
tendency
toward
light
brown,
which
was
beneficial
in
resisting
food
decomposition
caused
by
ultraviolet
light.
X-Ray
diffraction
analysis
(XRD)
Fourier-transform
Infrared
(FT-IR)
indicated
affected
structure
chitosan
films,
interaction
between
polyphenols
established
new
hydrogen
bonds.
Scanning
electron
microscopy
(SEM)
surface
PSO-containing
blend
rougher
compared
to
control
film,
roughness
as
content
increased.
Additionally,
contained
had
substantial
antibacterial
action,
particularly
against
pathogenic
E.
coli.
In
short,
novel
active
incorporated
present
broad
application
prospects
packaging
fresh-cut
meat
or
vegetables.
Therefore,
this
will
also
be
these
areas.
Chemistry & Biodiversity,
Год журнала:
2023,
Номер
20(11)
Опубликована: Сен. 30, 2023
Bacteria
are
associated
with
many
infections
that
affect
humans
and
present
antibiotic
resistance
mechanisms,
causing
problems
in
health
organisations
increased
mortality
rates.
Therefore,
it
is
necessary
to
find
new
antibacterial
agents
can
be
used
the
treatment
of
these
microorganisms.
Geopropolis
a
natural
product
from
stingless
bees,
formed
by
mixture
plant
resins,
salivary
secretions,
wax
soil
particles,
chemical
composition
this
diverse.
Thus,
study
aimed
evaluate
activity,
modulation
toxicity
geopropolis
extracts
Melipona
subnitida
(Ducke,
1910)
Scaptotrigona
depilis
(Moure,
1942)
against
standard
multi-resistant
Staphylococcus
aureus,
Escherichia
coli
Pseudomonas
aeruginosa
bacteria.
samples
were
collected
meliponary
located
Camaragibe,
Pernambuco,
Brazil.
To
determine
Minimum
Inhibitory
Concentration
(MIC)
we
performed
broth
microdilution
tests.
Mortality
tests
verify
extract
model
Drosophila
melanogaster.
The
microbiological
showing
M.
had
better
inhibitory
effects
compared
S.
depilis,
presenting
direct
activity
strains.
potentialized
effects,
suggesting
possible
synergy
did
not
used.
information
obtained
highlights
as
promising
first
bacterial
extracts,
addition
verifying
their
modulating
determining
Journal of Experimental Biology and Agricultural Sciences,
Год журнала:
2022,
Номер
10(2), С. 423 - 429
Опубликована: Апрель 30, 2022
Salmonella
enterica
serotype
typhi
is
a
gram-negative,
rod-shaped
bacterium,
and
has
flagella
with
the
human
body
as
its
only
reservoir.
Typhoid
fever
was
found
to
cause
21.7
million
illnesses
216,000
fatalities
worldwide
in
2000,
International
Vaccine
Institute
estimated
11.9
cases
129,000
deaths
low-
middle-income
countries
2010.
More
than
10
patients
were
infected
S.
each
year
mortality
rate
associated
more
0.1
patients.
Moreover,
it
also
drug
resistance
globally
which
makes
disease
dreadful.
Other
antibiotics,
various
flavonoids
showed
medicinal
effects
against
many
diseases
including
infection.
Flavonoids
are
type
of
plant
bioactive
metabolite
that
have
potential
efficacy.
The
goal
this
study
see
if
certain
(ellagic
acid,
eriodictyol,
naringenin)
could
interact
outer
membrane
osmoporin
(PDB
ID:
3uu2)
receptor
helps
inhibiting
growth.
To
look
for
probable
ligand-receptor
binding
relationships,
we
used
Pyrxmolecular
docking
software.
molecular
results
analyzed
using
Biovia
discovery
studio
visualizer.
current
discovered
selected
plant-based
compounds
interacted
an
receptor,
resulting
minimization
energy
range
of-6.6
-7.8
Kcal/mol.
Frontiers in Plant Science,
Год журнала:
2022,
Номер
13
Опубликована: Ноя. 29, 2022
Bacterial
fruit
blotch,
caused
by
the
seedborne
gram-negative
bacterium
Acidovorax
citrulli,
is
one
of
most
destructive
bacterial
diseases
cucurbits
(gourds)
worldwide.
Despite
its
prevalence,
effective
and
reliable
means
to
control
blotch
remain
limited.
Transcriptomic
analyses
tissue
culture-based
regeneration
processes
have
revealed
that
organogenesis-associated
cellular
reprogramming
often
associated
with
upregulation
stress-
defense-responsive
genes.
Yet,
there
limited
evidence
supporting
notion
reprogrammed
metabolism
regenerated
tissued
confers
bona
fide
antimicrobial
activity.
Here,
we
explored
anti-bacterial
activity
protocorm-like-bodies
(PLBs)
Phalaenopsis
aphrodite.
Encouragingly,
found
PLB
extract
was
potent
in
slowing
growth
A.
reducing
number
bacteria
attached
watermelon
seeds,
alleviating
disease
symptoms
seedlings
citrulli.
Because
can
be
fractionated
chemically,
predict
during
process
produces
metabolites
antibacterial
In
conclusion,
our
data
demonstrated
developing
PLBs
potential
using
orchid
discover
chemicals
disease.
