ZnO quantum dots reduce acquisition of huanglongbing pathogen by Diaphorina citri DOI
Wenhua Rao, Yue Qi, Shang Gao

и другие.

Pest Management Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 6, 2024

Abstract BACKGROUND Diaphorina citri Kuwayama is the main vector of Huanglongbing (HLB) pathogen Candidatus Liberibacter asiaticus ( C Las). Therefore, reducing Las acquisition by D. crucial for controlling spread HLB. RESULTS This study aimed to investigate effect ZnO quantum dots (ZnO QDs) on . The results showed that QDs were absorbed citrus plants and , inducing reactive oxygen species generation in intestine causing intestinal cell apoptosis. uptake rate was reduced 75% 22.3% after treatment with 2 5 mg ∙ mL −1 QDs, respectively, compared 100% control group. Transcription analysis significant changes expression genes related apoptosis, oxidative stress, DNA replication repair. CONCLUSION suggested could efficiently reduce providing a safe reliable tool HLB prevention control. © 2024 Society Chemical Industry.

Язык: Английский

Microwave-Assisted Synthesized ZnO@APTES Quantum Dots Exhibits Potent Antibacterial Efficacy Against Methicillin-Resistant Staphylococcus aureus Without Inducing Resistance DOI Creative Commons

Fangyuan Du,

Jingqi Niu,

Yu Hong

и другие.

International Journal of Nanomedicine, Год журнала: 2025, Номер Volume 20, С. 523 - 540

Опубликована: Янв. 1, 2025

Antibiotic resistance of many bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), has become a major threat to global health. Zinc Oxide Quantum dots (ZnO-QDs) show good antibacterial activity, but most them are insoluble in water, limiting their application range, and there is lack research on drug inducement. The water-soluble zinc oxide quantum modified by APTES (ZnO@APTES QDs) were prepared microwave assisted synthesis. Then ZnO@APTES QDs characterized through various methods. After confirmation synthesized QDs, its bactericidal effect MRSA was detected vitro vivo experiments, mechanism action analyzed. Characterization analysis revealed that the have particle size 5 nm. minimum inhibitory concentrations (MIC) determined be 64 µg mL-1 for Escherichia coli (E. coli) 32 MRSA. showed significant inhibition biofilm formation effectively disrupted mature biofilms. Notably, did not induce tolerance or even after 30 days repeated exposure, whereas antibiotics led rise bacterial MIC within 3 60-fold increase days. Mechanistic indicated positively charged interact with surfaces, altering membrane fluidity. Once inside generate reactive oxygen species (ROS), causing DNA damage cell death. Moreover, possessed biocompatibility demonstrated therapeutic efficacy against drug-resistant infections both macrophage mouse wound infection models. In summary, we highly effective shows strong other bacteria. holds potential development as new treatment agent combating antibiotic-resistant infections.

Язык: Английский

Процитировано

1
Light-driven zinc oxide quantum dots control pear fire blight disease by inhibiting pathogen growth and modulating plant defense response DOI Creative Commons
Lanlan Sun, Haodong Wang,

Cancan Qian

и другие.

Pesticide Biochemistry and Physiology, Год журнала: 2025, Номер 208, С. 106286 - 106286

Опубликована: Янв. 7, 2025

Язык: Английский

Процитировано

0
An eco‐friendly water‐soluble Cu2O@His for efficient control of citrus canker DOI Creative Commons
Wenhua Rao, Shang Gao,

Minyu Li

и другие.

Pest Management Science, Год журнала: 2025, Номер unknown

Опубликована: Март 12, 2025

Abstract BACKGROUND Citrus canker, a bacterial disease caused by Xanthomonas citri subsp. (Xcc), is one of the major threats to citrus industry. Inorganic copper (Cu) formulations such as Bordeaux mixture and Kocide 3000 are currently used control canker; however, they poorly water‐soluble have negligible plant transport, making systemic treatment canker difficult. RESULTS This study synthesized Cu 2 O@His one‐pot self‐assembly 2+ histidine for controlling canker. The results showed that had uniform size distribution (≈2.7 nm) good water solubility. It could disrupt cell membrane Xcc enter into cells destroy DNA, thereby inhibiting growth (half maximal inhibitory concentration = 7.4 μg mL −1 ) production virulence factors Xcc. was attributed its excellent dispersibility reactive oxygen species‐inducing ability. therapeutic efficacy transport were much better than those 3000. Additionally, it remarkable biosafety plants earthworms (lethal 50% >> 40 mg kg ). CONCLUSION provides new, eco‐friendly more efficient option control. © 2025 Society Chemical Industry.

Язык: Английский

Процитировано

0
ZnO quantum dots reduce acquisition of huanglongbing pathogen by Diaphorina citri DOI
Wenhua Rao, Yue Qi, Shang Gao

и другие.

Pest Management Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 6, 2024

Abstract BACKGROUND Diaphorina citri Kuwayama is the main vector of Huanglongbing (HLB) pathogen Candidatus Liberibacter asiaticus ( C Las). Therefore, reducing Las acquisition by D. crucial for controlling spread HLB. RESULTS This study aimed to investigate effect ZnO quantum dots (ZnO QDs) on . The results showed that QDs were absorbed citrus plants and , inducing reactive oxygen species generation in intestine causing intestinal cell apoptosis. uptake rate was reduced 75% 22.3% after treatment with 2 5 mg ∙ mL −1 QDs, respectively, compared 100% control group. Transcription analysis significant changes expression genes related apoptosis, oxidative stress, DNA replication repair. CONCLUSION suggested could efficiently reduce providing a safe reliable tool HLB prevention control. © 2024 Society Chemical Industry.

Язык: Английский

Процитировано

0