Advanced Materials,
Год журнала:
2023,
Номер
36(7)
Опубликована: Сен. 18, 2023
Microfluidics,
with
its
remarkable
capacity
to
manipulate
fluids
and
droplets
at
the
microscale,
has
emerged
as
a
powerful
platform
in
numerous
fields.
In
contrast
conventional
closed
microchannel
microfluidic
systems,
free-boundary
manufacturing
(FBMM)
processes
continuous
precursor
into
jets
or
relatively
spacious
environment.
FBMM
is
highly
regarded
for
superior
flexibility,
stability,
economy,
usability,
versatility
of
advanced
materials
architectures.
this
review,
comprehensive
overview
recent
advancements
provided,
encompassing
technical
principles,
material
manufacturing,
their
applications.
categorized
based
on
foundational
mechanisms,
primarily
comprising
hydrodynamics,
interface
effects,
acoustics,
electrohydrodynamic.
The
mechanisms
fluid
manipulation
are
thoroughly
discussed.
Additionally,
various
dimensions
ranging
from
zero-dimensional
three-dimensional,
well
diverse
applications
science,
biomedical
engineering,
engineering
presented.
Finally,
current
progress
summarized
future
challenges
prospected.
Overall,
review
highlights
significant
potential
tool
wide-ranging
International Journal of Molecular Sciences,
Год журнала:
2021,
Номер
22(4), С. 2011 - 2011
Опубликована: Фев. 18, 2021
Microfluidics
is
a
relatively
newly
emerged
field
based
on
the
combined
principles
of
physics,
chemistry,
biology,
fluid
dynamics,
microelectronics,
and
material
science.
Various
materials
can
be
processed
into
miniaturized
chips
containing
channels
chambers
in
microscale
range.
A
diverse
repertoire
methods
chosen
to
manufacture
such
platforms
desired
size,
shape,
geometry.
Whether
they
are
used
alone
or
combination
with
other
devices,
microfluidic
employed
nanoparticle
preparation,
drug
encapsulation,
delivery,
targeting,
cell
analysis,
diagnosis,
culture.
This
paper
presents
technology
terms
available
platform
fabrication
techniques,
also
focusing
biomedical
applications
these
remarkable
devices.
Advanced Functional Materials,
Год журнала:
2021,
Номер
32(14)
Опубликована: Дек. 16, 2021
Abstract
The
manufacture
of
bionic
materials
to
simulate
the
natural
counterparts
has
attracted
extensive
attention.
As
one
subcategories
biomimetic
materials,
development
artificial
enzyme
is
intensive
pursuing.
a
kind
enzyme,
nanozymes
are
dedicated
solve
limitations
enzymes.
In
recent
years,
attributed
explosive
nanotechnology,
biotechnology,
catalysis
science,
computational
design
and
theory
calculation,
research
on
made
great
progress.
To
highlight
these
achievements
help
researchers
understand
current
investigation
status
nanozyme,
state‐of‐the‐art
in
from
fabrication
bioapplications
summarized.
First
different
raw
summarized,
including
metal‐based,
metal‐free,
metal‐organic
frameworks‐based,
some
other
novel
matters,
which
applied
fabricate
nanozymes.
types
enzymes‐like
catalytic
activities
briefly
discussed.
Subsequently,
wide
applications
such
as
anti‐oxidation,
curing
diseases,
anti‐bacteria,
biosensing,
bioimaging
Finally,
challenges
faced
by
outlined
future
directions
for
advancing
nanozyme
outlooked.
authors
hope
this
review
can
inspire
fields
chemistry,
biology,
theoretical
computing,
contribute
Droplet,
Год журнала:
2022,
Номер
1(1), С. 11 - 37
Опубликована: Июль 1, 2022
Abstract
Droplet
manipulation
techniques
such
as
transport
and
merging
have
been
widely
used
in
many
fields
including
biology,
chemistry,
material
energy
applications.
Moreover,
droplet
strategies
extensively
investigated
reviewed
terms
of
placement
on
solid
surfaces.
However,
less
attention
has
paid
to
the
practice
technology
other
environments,
limiting
our
understanding
broadening
application.
In
this
article,
we
provided
an
overview
recent
progress
controlling
droplets
various
situations,
a
surface
mediated
by
passive
strategy
(Laplace
pressure
wettability
gradients)
active
(electric
field,
magnetic
light
heat).
We
also
presented
principle
detailed
application
bionic
surfaces
manipulation,
applications
prospects
were
summarized.
Biosensors and Bioelectronics X,
Год журнала:
2022,
Номер
10, С. 100106 - 100106
Опубликована: Янв. 8, 2022
The
attention
in
lab-on-a-chip
devices
with
their
potent
application
medical
engineering
has
prolonged
swiftly
over
the
last
ten
years.
Travelling
through
technology
development,
innovative
microfluidics
shown
enormous
potential
to
lift
biomedical
research
traditions
that
are
not
imaginable
using
conventional
techniques.
advances
arena
of
have
prompted
high-tech
uprisings
numerous
disciplines,
including
diagnostics,
single-cell
analysis,
micro-
and
nano
device
fabrication,
organ-in-chip
platforms,
med-tech
applications.
speedy
development
is
motivated
by
cumulative
cooperation
among
central
nanomaterials
microfluidic
aptitudes
range
Microfluidic
gadgets
presently
undertake
a
significant
part
organic,
synthetic,
designing
applications,
multiple
approaches
create
vital
channel
highlight
measurements.
In
this
review,
critical
assessments
on
frontiers
platforms
carried
out
towards
advancements
capabilities
for
new-edge
It
been
exhibited
offers
scope
benefits
contrasted
customary
strategies,
further
developed
controllability
consistency
specified
nanomaterial
attributes.
Herein,
authors
discussed
how
innumerable
empower
manufacture
systems
advanced
optical,
mechanical,
electrical
chemical,
bio-interfacial
properties
ranging
from
basics
microfluidics,
various
factors,
types,
fabrication
procedure
A
comprehensive
investigation
state-of-the-art
usage
field
steered
exemplarily
understand
advantages.
Moreover,
our
assessment
provides
an
interdisciplinary
overview
modern
microfabrication
strategies
can
be
adopted
academic
industrial
interests.
ACS Nano,
Год журнала:
2022,
Номер
16(10), С. 15705 - 15733
Опубликована: Окт. 13, 2022
Artificial
cells
are
constructed
to
imitate
natural
and
allow
researchers
explore
biological
process
the
origin
of
life.
The
construction
methods
for
artificial
cells,
through
both
top-down
or
bottom-up
approaches,
have
achieved
great
progress
over
past
decades.
Here
we
present
a
comprehensive
overview
on
development
their
properties
applications.
derived
from
lipids,
polymers,
lipid/polymer
hybrids,
cell
membranes,
colloidosome,
metal-organic
frameworks
coacervates.
They
can
be
endowed
with
various
functions
incorporation
proteins
genes
surface
encapsulated
inside
cells.
These
modulations
determine
including
producing
energy,
growth,
morphology
change,
division,
transmembrane
transport,
environmental
response,
motility
chemotaxis.
Multiple
applications
these
discussed
here
focus
therapeutic
used
as
carriers
materials
information
exchange
been
shown
function
targeted
delivery
systems
personalized
drugs.
Additionally,
substitute
impaired
function.
Enzyme
therapy
immunotherapy
using
an
intense
research.
Finally,
prospects
future
cell-mimic
broader
highlighted.
Abstract
The
origin
of
life
is
still
one
humankind's
great
mysteries.
At
the
transition
between
nonliving
and
living
matter,
protocells,
initially
featureless
aggregates
abiotic
gain
structure
functions
necessary
to
fulfill
criteria
life.
Research
addressing
protocells
as
a
central
element
in
this
diverse
increasingly
interdisciplinary.
authors
review
current
protocell
concepts
research
directions,
address
milestones,
challenges
existing
hypotheses
context
conditions
on
early
Earth,
provide
concise
overview
methods.
Nature Communications,
Год журнала:
2022,
Номер
13(1)
Опубликована: Янв. 25, 2022
Abstract
A
continuous
flow
cascade
of
multi-step
catalytic
reactions
is
a
cutting-edge
concept
to
revolutionize
stepwise
synthesis
yet
still
challenging
in
practical
applications.
Herein,
method
for
one-pot
catalysis
developed
by
combining
Pickering
emulsions
with
flow.
Our
involves
co-localization
different
catalytically
active
sub-compartments
within
droplets
emulsion
yielding
cell-like
microreactors,
which
can
be
packed
column
reactor
catalysis.
As
exemplified
two
chemo-enzymatic
the
chiral
cyanohydrins
and
ester,
5
−
420
fold
enhancement
efficiency
as
high
99%
enantioselectivity
were
obtained
even
over
period
80
240
h.
The
compartmentalization
effect
enriching-reactant
properties
arising
from
biomimetic
microreactor
are
theoretically
experimentally
identified
key
factors
boosting
regulating
kinetics
Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Фев. 21, 2024
Miniaturized
droplets,
characterized
by
well-controlled
microenvironments
and
capability
for
parallel
processing,
have
significantly
advanced
the
studies
on
enzymatic
evolution,
molecular
diagnostics,
single-cell
analysis.
However,
manipulation
of
small-sized
including
moving,
merging,
trapping
targeted
droplets
complex
biochemical
assays
subsequent
analysis,
is
not
trivial
remains
technically
demanding.
Among
various
techniques,
light-driven
methods
stand
out
as
a
promising
candidate
droplet
in
facile
flexible
manner,
given
features
contactless
interaction,
high
spatiotemporal
resolution,
biocompatibility.
This
review
therefore
compiles
an
in-depth
discussion
governing
mechanisms
underpinning
manipulation.
Besides,
light-responsive
materials,
representing
core
light-matter
interaction
key
character
converting
light
into
different
forms
energy,
are
particularly
assessed
this
review.
Recent
advancements
materials
most
notable
applications
comprehensively
archived
evaluated.
Continuous
innovations
rational
engineering
expected
to
propel
development
manipulation,
equip
with
enhanced
functionality,
broaden
routine
investigations.
