Lab on a Chip, Год журнала: 2024, Номер 24(7), С. 2039 - 2048
Опубликована: Янв. 1, 2024
Development of wearable sensing devices for minimally invasive and real time monitoring physiological information in ambulatory conditions.
Язык: Английский
Chemical Reviews, Год журнала: 2023, Номер 123(12), С. 7854 - 7889
Опубликована: Май 30, 2023
With the rising diabetic population, demand for glucose sensing devices has also been on an increasing trend. Accordingly, field of biosensors diabetes management witnessed tremendous scientific and technological advancements since introduction first enzymatic biosensor in 1960s. Among these, electrochemical hold considerable potential tracking dynamic profiles real time. The recent evolution wearable opened opportunities to use alternative body fluids a pain-free, noninvasive or minimally invasive manner. This review aims present comprehensive report about status promise sensors on-body monitoring. We start by highlighting importance how can contribute toward its effective then discuss mechanisms, such over time, different versions targeting various biofluids, multiplexed optimal management. Finally, we focus commercial aspects biosensors, starting with existing continuous monitors, followed other emerging technologies, concluding key prospects personalized connection autonomous closed-loop artificial pancreas.
Язык: Английский
Процитировано
193
Nature Electronics, Год журнала: 2024, Номер unknown
Опубликована: Сен. 23, 2024
Язык: Английский
Процитировано
46
Advanced Materials, Год журнала: 2023, Номер 36(2)
Опубликована: Сен. 15, 2023
Dermal interstitial fluid (ISF) is emerging as a rich source of biomarkers that complements conventional biofluids such blood and urine. However, the impact ISF sampling in clinical applications has been limited owing to challenges associated with extraction. The implementation microneedle-based wearable devices can extract dermal pain-free easy-to-use manner attracted growing attention recent years. Here, fully integrated touch-activated device based on laser-drilled hollow microneedle (HMN) patch for continuous sensing introduced. developed platform produce maintain required vacuum pressure (as low ≈ -53 kPa) collect adequate volumes (≈2 µL needle
Язык: Английский
Процитировано
44
TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 159, С. 116938 - 116938
Опубликована: Янв. 13, 2023
Язык: Английский
Процитировано
31
npj Flexible Electronics, Год журнала: 2023, Номер 7(1)
Опубликована: Сен. 1, 2023
Abstract As sweat biomarker levels are continuously changing over metabolism and daily activities, pathological physiological processes can be dynamically analyzed by wearable devices. The colorimetric skin-interfaced microfluidic devices that do not have external circuit modules exhibit enhanced deformability with a small footprint. However, it is difficult to achieve sampling time self-feedback for closed-loop systems. This review summarizes recent advances in valves biofluid management chrono-sampling, as well active triggers microfluidics self-feedback. After enumerating the current limitations temporal resolution reliability, we further point out few potential feasible strategies future developments.
Язык: Английский
Процитировано
31
Chemical Engineering Journal, Год журнала: 2024, Номер 495, С. 153382 - 153382
Опубликована: Июнь 21, 2024
Язык: Английский
Процитировано
12
Biosensors and Bioelectronics, Год журнала: 2025, Номер 277, С. 117289 - 117289
Опубликована: Фев. 20, 2025
Язык: Английский
Процитировано
2
Materials Science and Engineering R Reports, Год журнала: 2025, Номер 164, С. 100971 - 100971
Опубликована: Март 12, 2025
Язык: Английский
Процитировано
1
Nature Communications, Год журнала: 2025, Номер 16(1)
Опубликована: Март 18, 2025
Portable biosensors mainly focus on detecting biomarkers in biofluids but neglect the abundant skin stratum corneum, which are associated with functionality and integrity of barrier. Here, we propose a sensing patch designed for direct sampling situ quantification epidermal serine, an important biomarker healthcare. The consists porous hydrogel serine diffusion ion conduction, molecular imprinted polymer-based electrochemical sensor. By integrating customized handheld tester, system enables measurement levels. We demonstrate application this assessing moisturizing effect skincare product tracking recovery progress barrier function patient atopic dermatitis. Our work opens up potential scenario portable personalized Serine is authors introduce capable
Язык: Английский
Процитировано
1
Aggregate, Год журнала: 2025, Номер unknown
Опубликована: Апрель 22, 2025
ABSTRACT Recent advancements in hydrogel‐based flexible materials have revolutionized wound healing and monitoring strategies. These offer promising solutions for medical treatment real‐time diagnostics. Their rich water content, biocompatibility, tunable properties closely mimic the natural extracellular matrix, supporting regeneration. Unlike traditional materials, systems address critical issues such as material stability toxicity while integrating advanced devices. This review highlights latest innovations materials. It focuses on flexibility, potential integration with smart systems. The covers design principles fabrication techniques nanofibers, elastomers, conducting polymers. also discusses development of electronic skin innovative dressings. In addition, explains how sensing capabilities, stimuli‐responsive functions, antibacterial agents are incorporated into these Finally, article examines challenges future directions field. emphasizes transformative multifunctional improving continuous monitoring.
Язык: Английский
Процитировано
1