Neural Regeneration Research,
Год журнала:
2024,
Номер
20(2), С. 309 - 325
Опубликована: Март 1, 2024
Terahertz
biotechnology
has
been
increasingly
applied
in
various
biomedical
fields
and
especially
shown
great
potential
for
application
brain
sciences.
In
this
article,
we
review
the
development
of
terahertz
its
applications
field
neuropsychiatry.
Available
evidence
indicates
promising
prospects
use
spectroscopy
imaging
techniques
diagnosis
amyloid
disease,
cerebrovascular
glioma,
psychiatric
traumatic
injury,
myelin
deficit.
vitro
animal
experiments
have
also
demonstrated
therapeutic
value
technology
some
neuropsychiatric
diseases.
Although
precise
underlying
mechanism
interactions
between
electromagnetic
waves
biosystem
is
not
yet
fully
understood,
research
progress
shows
noninvasive
diagnostic
applications.
However,
biosafety
radiation
requires
further
exploration
regarding
two-sided
efficacy
practical
This
demonstrates
that
to
be
a
method
neuropsychiatry
based
on
unique
advantages.
Advanced Materials,
Год журнала:
2024,
Номер
36(14)
Опубликована: Янв. 5, 2024
High-sensitive
metasurface-based
sensors
are
essential
for
effective
substance
detection
and
insightful
bio-interaction
studies,
which
compress
light
in
subwavelength
volumes
to
enhance
light-matter
interactions.
However,
current
methods
improve
sensing
performance
always
focus
on
optimizing
near-field
response
of
individual
meta-atom,
fingerprint
recognition
bio-substances
necessitates
several
pixelated
metasurfaces
establish
a
quasi-continuous
spectrum.
Here,
novel
strategy
is
proposed
achieve
Terahertz
(THz)
refractive
sensing,
based
surface
waves
(SWs).
Leveraging
the
long-range
transmission,
strong
confinement,
interface
sensitivity
SWs,
metasurface-supporting
SWs
excitation
propagation
experimentally
verified
integrations.
Through
wide-band
information
collection
sensor
not
only
facilitates
up
215.5°/RIU,
but
also
enables
simultaneous
resolution
multiple
within
continuous
By
covering
5
µm
thickness
polyimide,
quartz
silicon
nitride
layers,
maximum
phase
change
91.1°,
101.8°,
126.4°
obtained
THz
band,
respectively.
Thus,
this
broadens
research
scope
metasurface-excited
introduces
paradigm
ultrasensitive
functions.
Photonics Research,
Год журнала:
2023,
Номер
12(2), С. 194 - 194
Опубликована: Дек. 4, 2023
The
terahertz
(THz)
wave
is
at
the
intersection
between
photonics
and
electronics
in
electromagnetic
spectrum.
Since
vibration
mode
of
many
biomedical
molecules
weak
interaction
inside
fall
THz
regime,
utilizing
radiation
as
a
signal
source
to
operate
substance
information
sensing
has
its
unique
advantages.
Recently,
metamaterial
sensor
(metasensor)
greatly
enhanced
substances
spectral
selectivity
on
subwavelength
scale.
However,
most
past
review
articles
have
demonstrated
metasensor
terms
their
structures,
applications,
or
materials.
Until
recently,
with
rapid
development
metasensing
technologies,
molecular
paid
much
more
attention
platform
metasensors.
In
this
review,
we
comprehensively
introduce
for
detecting
not
only
featureless
refractive
index
but
also
vibrational/chiral
analytes.
objectives
are
improve
specificity
either
by
chemical
material-assisted
analyte
capture
physical
information.
Later,
boost
absorption
features
certain
frequency,
resonant
responses
metasensors
can
be
tuned
vibrational
modes
target
molecules,
while
frequency
multiplexing
techniques
reviewed
enhance
broadband
spectroscopic
fingerprints.
chiral
summarized
specific
identification
molecules.
Finally,
potential
prospects
next
generation
discussed.
Compared
metasensing,
platforms
accelerated
material
modification
will
lead
greater
impact
advancement
trace
detection
conformational
dynamics
biomolecules
practical
applications.
Abstract
The
molecular
fingerprint
sensing
technology
based
on
metasurface
has
unique
attraction
in
the
biomedical
field.
However,
terahertz
(THz)
band,
existing
designs
multi-pixel
or
angle
multiplexing
usually
require
more
analyte
amount
possess
a
narrower
tuning
bandwidth.
Here,
we
propose
novel
single-pixel
graphene
metasurface.
Based
synchronous
voltage
tuning,
this
enables
ultra-wideband
(
$$\sim$$
∼
1.5
THz)
enhancement
of
trace
analytes,
including
chiral
optical
isomers,
with
limit
detection
(LoD)
≤
0.64
μg/mm
2
.
signal
17.4
dB)
originates
from
electromagnetically
induced
transparency
(EIT)
effect
excited
by
metasurface,
and
ideal
overlap
between
light
field
constrained
single-layer
(SLG)
ultra-thin
analyte.
Meanwhile,
due
to
nonlinear
mechanism
absorption
envelope
distortion
is
inevitable.
To
solve
problem,
universal
spectrum
inversion
model
developed
for
first
time,
restoration
standard
fingerprints
reaches
R
max
≥
0.99.
In
addition,
asynchronous
provides
an
opportunity
realizing
dynamic
reconfiguration
EIT
resonance
slow
modulation
broadband
range.
This
work
builds
bridge
THz
potential
applications
active
spatial
modulators,
devices
imaging
equipments.
Applied Physics Reviews,
Год журнала:
2024,
Номер
11(3)
Опубликована: Июль 10, 2024
Structural
symmetry
plays
a
pivotal
role
in
the
emergence
of
symmetry-protected
bound
states
continuum
(BICs),
often
observed
at
Γ-point
within
first
Brillouin
zone.
However,
structural
is
not
an
absolute
requirement
for
formation
BICs
Γ-point.
In
this
work,
we
demonstrate
that
all-dielectric
metasurfaces
and
photonic
crystal
slabs,
made
dimer
nanostructures
with
different
sizes
shapes,
can
sustain
We
show
nature
these
well
preserved,
irrespective
size
mismatch/difference,
as
long
center-to-center
distance
between
two
nanodisks
equal
to
half
lattice
constants
superunit
cell.
The
are
transformed
into
quasi-BICs
(QBICs)
finite
quality
(Q)
factors
by
varying
interspacing
nanodisks.
Multipole
decomposition
indicates
BIC
primarily
governed
toroidal
dipole,
secondary
contribution
from
magnetic
dipole
quadrupole.
Furthermore,
establish
such
robust
against
shape
Notably,
observe
Q-factor
QBICs
right
displaced
along
y-axis
three
orders
magnitude
higher
than
those
x-axis,
suggesting
effective
approach
realizing
ultrahigh-Q
resonances.
Finally,
present
experimental
demonstration
fabricating
silicon
slabs
nanoholes.
trend
measured
Q-factors
resonant
wavelengths
shows
good
agreement
theoretical
predictions.
maximum
up
22
633.
These
results
only
advance
our
understanding
compound
but
also
hold
great
promise
enhancing
light–matter
interactions.
Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 27, 2024
Abstract
As
a
2D
metamaterial,
metasurfaces
offer
an
unprecedented
avenue
to
facilitate
light‐matter
interactions.
The
current
“one‐by‐one
design”
method
is
hindered
by
time‐consuming,
repeated
testing
within
confined
space.
However,
intelligent
design
strategies
for
metasurfaces,
limited
data‐driven
properties,
have
rarely
been
explored.
To
address
this
gap,
data
iterative
strategy
based
on
deep
learning,
coupled
with
global
optimization
network
proposed,
achieve
the
customized
of
chiral
metasurfaces.
This
methodology
applied
precisely
identify
different
molecules
in
label‐free
manner.
Fundamentally
from
traditional
approach
collecting
purely
through
simulation,
proposed
generation
encompasses
entire
space,
which
inaccessible
conventional
methods.
dataset
quality
significantly
improved,
21‐fold
increase
number
structures
exhibiting
desired
circular
dichroism
(CD)
response
(>0.6).
method's
efficacy
validated
monolayer
structure
that
easily
prepared,
demonstrating
advanced
sensing
abilities
enantiomer‐specific
analysis
bio‐samples.
These
results
demonstrate
superior
capability
schemes
photonic
and
potential
metasurface‐based
platforms
calibration‐free
biosensing
applications.
will
accelerate
development
complex
systems
rapid
molecular
detection,
spectroscopic
imaging,
other
Nanophotonics,
Год журнала:
2024,
Номер
13(4), С. 463 - 475
Опубликована: Фев. 2, 2024
Abstract
The
metasurface
refractive
index
sensor
has
a
high
degree
of
tunability
and
flexibility,
providing
excellent
performance
for
precision
sensing
applications.
absorber
with
metallic
structure
been
hindered
in
further
applications
due
to
the
inherent
Ohmic
loss
material.
In
this
study,
dual
nanorod
based
on
semiconductor
Si
was
designed,
introducing
symmetry-breaking
excite
ultra-narrow
q-BIC
resonance
peaks
Fano
line
shapes.
Both
are
located
near-infrared
region,
multipole
analysis
shows
that
strong
field
enhancement
effect
is
induced
by
magnetic
dipole.
Experimental
results
demonstrate
potential
provide
dual-channel
detection
while
achieving
sensitivity
Q-factor.
We
believe
device
exhibits
outstanding
practicality,
reference
development
application
biological
environmental
sensors.
Biosensors,
Год журнала:
2023,
Номер
14(1), С. 3 - 3
Опубликована: Дек. 21, 2023
In
recent
decades,
THz
metamaterials
have
emerged
as
a
promising
technology
for
biosensing
by
extracting
useful
information
(composition,
structure
and
dynamics)
of
biological
samples
from
the
interaction
between
wave
samples.
Advantages
with
include
label-free
non-invasive
detection
high
sensitivity.
this
review,
we
first
summarize
different
sensing
principles
modulated
metamaterial
bio-analyte
detection.
Then,
compare
various
resonance
modes
induced
in
range
enhancement.
addition,
non-conventional
materials
used
to
improve
performance
are
evaluated.
We
categorize
review
types
using
metamaterials.
Finally,
discuss
future
perspective
biosensing.
Nanotechnology Reviews,
Год журнала:
2024,
Номер
13(1)
Опубликована: Янв. 1, 2024
Abstract
Terahertz
metasurface
(THz-MS)
biosensor
is
a
hybrid
technology
that
combines
terahertz
time-domain
spectroscopy
and
for
the
detection
of
biomolecules
cells.
Compared
with
traditional
strategies,
it
label-free,
non-invasive,
time-saving,
easy
to
operate.
However,
three
fundamental
issues,
namely,
low
sensitivity,
specificity,
drastic
water
absorption,
hinder
development
THz-MS
biosensors
clinical
application.
Recently,
numerous
studies
have
been
performed
solve
these
problems,
results
show
great
potential
sensitive
nucleotides,
proteins,
Therefore,
important
summarize
in
biomedical
detection.
In
this
review,
we
summarized
mechanism,
manufacturing,
implementation
biosensors.
Then,
strategies
improve
selectivity,
means
reduce
absorption
are
presented.
Sensitivity
can
be
improved
by
suppressing
electromagnetic
radiation
strengthening
interaction
between
target
molecules
meta-atoms.
Antibodies
aptamers
most
effective
improving
specificity.
Microfluidics
hydrogels
two
ways
absorption.
Subsequently,
applications
nucleotide,
cells
summarized.
Finally,
prospects
future
outlined.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
16(12), С. 15193 - 15201
Опубликована: Март 16, 2024
Chiral
metasurfaces
are
capable
of
generating
a
huge
superchiral
field,
which
has
great
potential
in
optoelectronics
and
biosensing.
However,
the
conventional
fabrication
process
suffers
greatly
from
time
consumption,
high
cost,
difficult
multilayer
alignment,
hinder
its
commercial
application.
Herein,
we
propose
twisted
stacking
carbon-based
terahertz
(THz)
chiral
metasurface
(TCM)
based
on
laser-induced
graphene
(LIG)
technology.
By
repeating
two-step
sticking
polyimide
film,
followed
by
laser
direct
writing,
two
layers
TCM
aligned
automatically
fabrication.
Laser
manufacturing
also
brings
such
processing
speed
that
with
size
15
×
mm
can
be
prepared
60
s.
In
addition,
due
to
greater
dissipation
LIG
than
metals
THz
band,
giant
circular
dichroism
(CD)
+99.5
−99.6%
is
experimentally
realized.
The
biosensing
bovine
serum
albumin
enhanced
proposed
TCMs
then
demonstrated.
A
wide
sensing
range
(0.5–50
mg
mL–1)
good
sensitivity
[ΔCD:
2.09%
(mg
mL–1)−1,
Δf:
0.0034
mL–1)−1]
proved.
This
LIG-based
provides
an
environment-friendly
platform
for
research
application
rapid
low-cost
