Cyclodextrin in drug delivery: Exploring scaffolds, properties, and cutting-edge applications

International Journal of Pharmaceutics, Год журнала: 2024, Номер 662, С. 124485 - 124485

Опубликована: Июль 17, 2024

Язык: Английский

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Air plasma assisted directional electrodeposition of Ag nanoparticles on carbon cloth for electrochemical detection of rutin

Microchimica Acta, Год журнала: 2025, Номер 192(4)

Опубликована: Март 6, 2025

Язык: Английский

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Rutin‐Associated Hepatoprotection: A Review of Mechanisms and Therapeutic Prospects

Basic & Clinical Pharmacology & Toxicology, Год журнала: 2025, Номер 136(6)

Опубликована: Май 13, 2025

Liver disorders pose a considerable global health challenge, accompanied by rising mortality rates. Current therapeutic strategies, though effective, often face limitations due to adverse effects and resistance, prompting the exploration of alternative treatments, particularly safer natural compounds. Rutin, widely available bioflavonoid, has emerged as promising candidate owing its varied pharmacological properties. We conducted comprehensive search on PubMed Web Science using following keywords: 'rutin', 'liver diseases', 'hepatoprotection', 'clinical observations', 'mechanisms, pharmacology' various combinations these terms. This review systematically examines rutin's potential in hepatic disorders, focusing molecular mechanisms, inflammatory pathways, oxidative stress hepatocellular protection. analyse existing evidence supporting hepatoprotective efficacy, identify cellular targets evaluate applications liver diseases. Our systematic analysis provides theoretical support for developing rutin-based therapies disease management identifies future research directions clinical applications.

Язык: Английский

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Regulating Catalytic Oxidation Enantiomers Behavior by Imparting Chiral Microenvironment in Zr‐Based Metal–Organic Frameworks

Small, Год журнала: 2024, Номер 20(44)

Опубликована: Июль 5, 2024

Chiral inversions of enantiomers have significantly different biological activities, so it is important to develop simple and effective methods efficiently identify optically pure compounds. Inspired by enzyme catalysis, the construction chiral microenvironments resembling pockets in pore space structure metal-organic frameworks (MOFs) achieve asymmetric enantioselective recognition catalysis has become a new research hotspot. Here, super-stable porphyrin-containing material PCN-224 constructed solvothermal method microenvironment around existing catalytic site created post-synthesis modifications histidine (His) enantiomers. Experimental theoretical calculations results show that modulation ligands Zr oxide clusters produces spatial resistances, which can greatly affect adsorption level enantiomeric molecules tryptophan guests, resulting good property material. It provides ideas possibilities for future catalysis.

Язык: Английский

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An electrochemical sensor based on porous heterojunction hollow NiCo-LDH/Ti3C2Tx MXenes composites for the detection of quercetin in natural plants

Microchimica Acta, Год журнала: 2024, Номер 191(10)

Опубликована: Сен. 3, 2024

Язык: Английский

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Catalytic amplification platform based on Fe2O3 nanoparticles decorated graphene nanocomposite for highly sensitive detection of rutin

Nanoscale Advances, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Fe 2 O 3 nanoparticles decorated graphene nanocomposites prepared by one-pot pyrolysis exhibit high performance for the detection of rutin.

Язык: Английский

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Sea urchin-like Ni3(HITP)2 as the substrate of molecular imprinted polymer: the voltammetric mechanism for sensitive detection of dopamine

Microchimica Acta, Год журнала: 2024, Номер 191(10)

Опубликована: Сен. 17, 2024

Язык: Английский

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Trimetallic ZIFs-derived nanoarchitecture for portable wireless electrochemical determination of chlorogenic acid in natural medicine and food samples

Microchemical Journal, Год журнала: 2024, Номер 207, С. 111877 - 111877

Опубликована: Окт. 9, 2024

Язык: Английский

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Recent electrochemical applications of Two-Dimensional nanoclays based materials

Microchemical Journal, Год журнала: 2024, Номер unknown, С. 111908 - 111908

Опубликована: Окт. 1, 2024

Язык: Английский

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