Diaper-based wearable SERS sensing system with a silver nano dual-structure composite hydrogel for the detection of biomarkers and pH in urine

Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155207 - 155207

Опубликована: Авг. 26, 2024

Язык: Английский

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Advanced biomaterials for targeting mature biofilms in periodontitis therapy

Bioactive Materials, Год журнала: 2025, Номер 48, С. 474 - 492

Опубликована: Фев. 27, 2025

Язык: Английский

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A mussel-inspired wet-adhesive prolonged-acting antibacterial hydrogels for the treatment of periodontitis

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161262 - 161262

Опубликована: Март 1, 2025

Язык: Английский

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Polymer-based antimicrobial strategies for periodontitis

Frontiers in Pharmacology, Год журнала: 2025, Номер 15

Опубликована: Янв. 6, 2025

Periodontitis is a chronic inflammatory condition driven by plaque-associated microorganisms, where uncontrolled bacterial invasion and proliferation impair host immune responses, leading to localized periodontal tissue inflammation bone destruction. Conventional therapies face challenges, including incomplete microbial clearance the rise of antibiotic resistance, limiting their precision effectiveness in managing periodontitis. Recently, nanotherapies based on polymeric materials have introduced advanced approaches antimicrobial therapy through diverse mechanisms. This review explored specific mechanisms, emphasizing design polymer-based agents that employ individual or synergistic actions, evaluated innovations limitations current strategies while forecasting future trends development for

Язык: Английский

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Harnessing the functional role of polymeric nanocomposite in dental caries disease: A comprehensive review

Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100433 - 100433

Опубликована: Март 1, 2025

Язык: Английский

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Design and application of antimicrobial nanomaterials in the treatment of periodontitis

Nanomedicine, Год журнала: 2025, Номер unknown, С. 1 - 17

Опубликована: Март 5, 2025

Periodontitis is a chronic inflammatory disease induced by the microbiome, leading to destruction of periodontal structures and potentially resulting in tooth loss. Using local drug delivery systems as an adjunctive therapy scaling root planning periodontitis promising strategy. However, this administration method's effectiveness constrained complexity environment. Nanomaterials have demonstrated significant potential antibacterial treatment periodontitis, attributed their controllable size, shape, surface charge, high design flexibility, reactivity, specific area. In review, we summarize complex microenvironment difficulties explicitly reviewing application strategies nanomaterials with unique properties distinct periodontitis. Furthermore, review discusses limitations current research, proposes feasible solutions, explores prospects for using context.

Язык: Английский

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A Sequential Therapeutic Strategy Based on Aptamer/Polymer‐Functionalized PDA/Ag for Precise Acinetobacter Baumannii Imaging and Pneumonia Treatment

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 30, 2025

Abstract Acinetobacter baumannii ( A. ) is a leading cause of pneumonia. Conventional antibiotics can increase the risk drug resistance and non‐specifically harm microflora, disrupting their balance. In addition to pathogenic bacteria, lung inflammation also damages tissue. This study develops an aptamer/polymer‐functionalized mesoporous polydopamine/silver nanocomposite (Apt/ODEA‐PDA/Ag‐ICG) specifically target sequentially exhibit antibacterial/antioxidative properties for pneumonia treatment. After synthesizing polyzwitterion (ODEA), polymer/aptamer conjugated with PDA/Ag core, ICG further labeled fabricate nanocomposite. Upon intratracheal instillation, nanocomposites penetrate mucus barrier help polyzwitterions. The precisely targets through specific recognition by aptamer, without affecting other microflora. Moreover, distributed disorderedly within polymer. near core contributes high NIR‐I absorbance good photothermal ability. from acts as fluorescent molecule imaging. Furthermore, efficiently exhibits synergistic antibacterial activity owing acidic environment/heat‐accelerated Ag + release effect. Importantly, alongside release, antioxidant ability PDA scavenges reactive oxygen species alleviates inflammation, thereby accelerating summary, provide alternative approach designing advanced systems.

Язык: Английский

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Advances of functional nanomaterials as either therapeutic agents or delivery systems in the treatment of periodontitis

Biomaterials Advances, Год журнала: 2025, Номер 175, С. 214326 - 214326

Опубликована: Апрель 27, 2025

Язык: Английский

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Biomimicry-Inspired Zwitterionic Polyurethane Used for Vascular Implants Showing Water-induced Stiffening and Preventing Intimal Hyperplasia in Stent

Biomaterials, Год журнала: 2025, Номер 322, С. 123394 - 123394

Опубликована: Май 6, 2025

Язык: Английский

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A Review on Recently Developed Antibacterial Composites of Inorganic Nanoparticles and Non-Hydrogel Polymers for Biomedical Applications

Nanomaterials, Год журнала: 2024, Номер 14(21), С. 1753 - 1753

Опубликована: Окт. 31, 2024

Development of new antibacterial materials for solving biomedical problems is an extremely important and very urgent task. This review aims to summarize recent articles (from the last five mostly three years) on nanoparticle/polymer composites applications. Articles polymeric nanoparticles (NPs) hydrogel-based systems were not reviewed, since we focused our attention matrix with at least one inorganic filler in form NPs. The fields application newly developed NPs/polymer are described, along their composition synthetic approaches that allow researchers succeed preparing effective composite medical healthcare purposes.

Язык: Английский

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