Theranostic Role of Advanced Nanotechnological Tools in Early Brain Metastases in Lung Cancer: An Updated Review

International Journal of Nanomedicine, Год журнала: 2025, Номер Volume 20, С. 7215 - 7232

Опубликована: Июнь 1, 2025

Язык: Английский

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Synergistic Gas Therapy and Targeted Interventional Ablation With Size‐Controllable Arsenic Sulfide (As₂S₃) Nanoparticles for Effective Elimination of Localized Cancer Pain

Small, Год журнала: 2024, Номер unknown

Опубликована: Окт. 2, 2024

Abstract The elimination of localized cancer pain remains a globally neglected challenge. A potential solution lies in combining gas therapy with targeted interventional ablation therapy. In this study, HA‐As 2 S 3 nanoparticles controlled sizes are synthesized using different molecular weights sodium hyaluronate (HA) as supramolecular scaffold. Initially, HA co‐assembles arsenic ions (As 3+ ) via coordinate bonds, forming scaffold intermediates. These intermediates, varying size, then react sulfur to produce size‐controlled particles. This approach demonstrates that enable precise control over the particle size sulfide, offering straightforward and environmentally friendly method for synthesizing metal sulfide an acidic environment, release hydrogen sulfide(H S) As . released directly damage tumor mitochondria, leading substantial reactive oxygen species (ROS) production from mitochondria. Concurrently, H inhibits activity catalase (CAT) complex IV, preventing beneficial decomposition ROS disrupting electron transfer mitochondrial respiratory chain. Consequently, it is found significantly enhances induced by nanodrugs, effectively killing local tumors ultimately eliminating mice.

Язык: Английский

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Research progress of paclitaxel nanodrug delivery system in the treatment of triple-negative breast cancer

Materials Today Bio, Год журнала: 2024, Номер 29, С. 101358 - 101358

Опубликована: Ноя. 23, 2024

Язык: Английский

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Polyethyleneimine-modified Laminarin nanoparticles as a novel vaccine adjuvant for ovalbumin to enhance the immune responses

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 139157 - 139157

Опубликована: Дек. 1, 2024

Язык: Английский

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Challenges in exosome nanovesicle-based drug delivery and diagnostics

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 203 - 252

Опубликована: Ноя. 29, 2024

Язык: Английский

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