Xolography for Biomedical Applications: Dual‐Color Light‐Sheet Printing of Hydrogels With Local Control Over Shape and Stiffness
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 27, 2025
Abstract
Current
challenges
in
tissue
engineering
include
creation
of
extracellular
environments
that
support
and
interact
with
cells
using
biochemical,
mechanical,
structural
cues.
Spatial
control
over
these
cues
is
currently
limited
due
to
a
lack
suitable
fabrication
techniques.
This
study
introduces
Xolography,
an
emerging
dual‐color
light‐sheet
volumetric
printing
technology,
achieve
mechanical
features
for
hydrogel‐based
photoresins
at
micro‐
macroscale
while
within
minutes.
A
water‐soluble
photoswitch
photoinitiator
system
library
naturally‐derived,
synthetic,
thermoresponsive
hydrogels
Xolography
are
proposed.
Centimeter‐scale,
3D
constructs
positive
20
µm
negative
≈100
fabricated
properties
(compressive
moduli
0.2
kPa–6.5
MPa).
Notably,
switching
from
binary
grayscaled
light
projection
enables
spatial
stiffness
(0.2–16
kPa).
As
proof
concept,
leveraged
introduce
reversible
anisotropic
shape
changes
beyond
isometric
shrinkage.
viable
cell
aggregates
finally
demonstrated,
laying
the
foundation
cell‐laden
dynamic,
cell‐instructive
tunable
fast
one‐step
process.
Overall,
innovations
unlock
unique
possibilities
across
multiple
biomedical
applications.
Язык: Английский
The road ahead in materials and technologies for volumetric 3D printing
Nature Reviews Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 18, 2025
Язык: Английский
Linear volumetric additive manufacturing of zirconia from a transparent photopolymerizable ceramic slurry via Xolography
Open Ceramics,
Год журнала:
2024,
Номер
19, С. 100655 - 100655
Опубликована: Авг. 10, 2024
Advanced
ceramics
printed
with
photon-based
additive
manufacturing
deals
anisotropic
mechanical
properties
from
the
layer-by-layer
manufacturing.
Motivated
by
success
in
using
highly
filled
transparent
slurries
containing
nanoparticles
for
powder-based
two-photon-polymerization
(2PP)
advanced
ceramic
printing,
this
works
approach
is
transfer
to
Xolography,
a
volumetric
technology
based
on
linear
two-photon
excitation
and
without
recoating
steps.
This
paper
reports
results
of
preliminary
investigation
optimizing
photocurable
slurry
requirements
Xolography
terms
transparency,
over
significantly
larger
mean
free
path,
compared
2PP.
A
feedstock
70
%
weight
fraction
particles
(∼30
vol%)
exhibiting
an
exceptionally
high
degree
transparency
relevant
wavelength
range
400–800
nm
was
prepared
5
zirconia
nanoparticles.
The
attributed
near-monomodal
particle
size
distribution
used.
Язык: Английский
Xolography for 3D Printing in Microgravity
Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 13, 2024
Abstract
Xolography
is
a
volumetric
3D
printing
technique
utilizing
intersecting
light
beams
within
volume
of
photopolymer
for
spatially
controlled
photopolymerization.
Unlike
layer‐based
methods,
creates
structures
continuously
closed
vat,
eliminating
the
prevalent
need
support
and
allowing
full
geometrical
freedom
at
high
speeds.
The
working
principle
does
not
rely
on
gravity,
making
an
outstanding
technology
additive
manufacturing
under
microgravity
conditions
as
illustrated
in
set
experiments
during
parabolic
flight
campaign.
environment
obviates
rheology
control
resins,
enabling
use
low‐viscosity
formulations
(e.g.,
11
mPa
s)
while
maintaining
fast
precise
acrylic
polymer
resins
hydrogels.
Xolography's
speed
reliability
facilitate
rapid
iterations
print
task
between
Earth's
gravity
conditions.
This
capability
positions
ideal
tool
material
research
space,
offering
significant
cost
efficiency
advantages
over
traditional
methods.
Язык: Английский