Enhanced carrier separation and decreased reaction barrier in cobalt-doped CdIn2S4 nanosheets for photocatalytic hydrogen evolution
Journal of Colloid and Interface Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Efficient Al–H3NTB-MOG ECL Emitter with Self-Enhanced and AIECL Performance for Ultrasensitive Sensing of miRNA-141 Combined with a Y-Shaped Multiregion Dual-Drive DNA Walker
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 16, 2025
In
this
work,
using
Al-H3NTB-MOG
with
self-enhanced
and
aggregation-induced
electrochemiluminescence
(AIECL)
performance
as
an
efficient
emitter,
a
biosensor
based
on
Y-shaped
multiregion
dual-drive
DNA
walker
was
constructed
for
the
sensitive
detection
of
miRNA-141.
Notably,
4,4',4″-nitrilotribenzoic
acid
(H3NTB)
selected
luminescent
ligand
ECL
property
co-reactive
tertiary
amine
in
its
structure.
Al3+
served
central
ion
to
coordinate
H3NTB
form
three-dimensional
porous
gel
structure,
which
restricted
internal
rotation
vibration
benzene
molecules
exhibited
excellent
AIECL
property.
More
interestingly,
N-2-hydroxyethylpiperazine-N'-ethane-sulfonic
(HEPES)
chosen
system
buffer,
could
not
only
stabilize
test
environment
but
also
play
co-reaction
compensation
role
compensate
consumption
groups
process,
then
significantly
resulting
better
stability
response.
Besides,
dynamic
signal
amplification
established
synergistic
effect
rolling
cycle
(RCA)
process
ionic
cleavage
at
both
ends
nanostructure
assembled
by
catalytic
hairpin
self-assembly
(CHA)
reaction.
Specifically,
two
long
chains
abundant
recognition
regions
were
formed
RCA
reaction
walker,
simultaneously
walk
along
predesigned
tracks
shear
specific
sites
from
directions,
effectively
improving
efficiency.
that
way,
realized
miRNA-141
10
aM
1
nM
range
limit
low
6.48
aM.
Язык: Английский
Dual‐Mode Detection of RNA Demethylation Protein ALKBH3 Using a Two‐Legged DNA‐Walker‐Mediated BiOI/In2O3‐Gated Organic Photoelectrochemical Transistor Biosensor
Small,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 19, 2025
Abstract
Organic
photoelectrochemical
transistor
(OPECT)
biosensors
have
emerged
as
prevalent
candidates
for
bioanalytical
technologies
because
of
their
intrinsic
amplification
properties
and
excellent
detection
performance.
Herein,
a
novel
OPECT
biosensor
analyzing
the
RNA
demethylation
protein
ALKBH3
is
developed.
A
BiOI/In
2
O
3
type‐II
heterojunction
employed
photoactive
material
gate,
an
organic
semiconductor,
poly(3,4‐ethylenedioxythiophene):
poly(styrenesulfonic)
(PEDOT:PSS),
used
channel
modification
material.
ALKBH3‐mediated
demethylation,
switch,
triggered
trans‐cleavage
activity
CRISPR‐Cas12a
system,
which
subsequently
leads
to
failure
in
formation
bipedal
DNA
walker.
Contrarily,
ferrocenecarboxylic
acid
(FcA),
acts
effective
electron
donor,
cannot
be
captured,
leading
modulation
gating
characteristics
degradation
current
response.
Compared
conventional
method,
exhibits
higher
sensitivity
lower
limit
protein,
thereby
facilitating
monitoring
changes
under
effect
environmental
pollutants
demonstrating
crucial
biomarker
potential
evaluating
its
toxicological
effects.
Язык: Английский