ACS Nano, Год журнала: 2024, Номер 18(42), С. 29223 - 29232
Опубликована: Окт. 11, 2024
Fibroblast growth factor receptor 1 (FGFR1) is emerging as a promising molecular target of lung cancer, and various FGFR1 inhibitors have exhibited significant therapeutic effects on cancer in preclinical research. Due to their low targeting ability or bioavailability, direct administration these may cause side effects. Herein, hydrogelator, Nap-Phe-Phe-Phe-Glu-Thr-Glu-Leu-Tyr-OH (
Язык: Английский
Bone Research, Год журнала: 2025, Номер 13(1)
Опубликована: Апрель 7, 2025
Язык: Английский
Процитировано
2
Biomacromolecules, Год журнала: 2025, Номер unknown
Опубликована: Янв. 8, 2025
The rapid development of flexible electronics has led to unprecedented social and economic improvements. But conventional power devices cannot adapt the advances electronics. Triboelectric nanogenerators (TENGs) have been used as robust sources transform ambient mechanical energy into electricity, thus meeting requirements Hydrogels are widely for soft bioelectronics owing decent stretchability biocompatibility. This Review presents recent progress in use hydrogels TENGs self-powered hydrogel bioelectronics, including synthesis, fabrication, their applications wearable electricity generation, active sensing, therapeutics. Hydrogel-enabled emerging a novel form bioelectronics. We provided critical analysis insights future opportunities directions this rapidly evolving field. These advancements will push boundaries contribute personalized healthcare solutions.
Язык: Английский
Процитировано
0
Medical Science Monitor, Год журнала: 2025, Номер 31
Опубликована: Янв. 10, 2025
The oral cavity is an open and complicated structure with a variety of factors affecting topical medications. physical chemical surroundings the can influence action free drugs. Thus, drug delivery system serve as support or carrier. Hydrogels are prospective tissue engineering biomaterials that demonstrate immense potential for regeneration delivery. crosslinked polymer chains 3-dimensional network take up larger volumes liquid have soft, porous closely resembles living tissue. protect active from systemic elimination, increase bioavailability absorption into cells, release modify therapeutic immediately after dosing. In this review, we introduce classification hydrogels, application hydrogels in diseases (periodontal disease, endodontics, mucosal alveolar surgery, cancer, maxillofacial bone defects, implantation), summarize synthesis methods applications discuss possible directions future development which will provide new idea formulation production more advantageous efficient system.
Язык: Английский
Процитировано
0
Smart Medicine, Год журнала: 2025, Номер 4(1)
Опубликована: Фев. 26, 2025
Glucocorticoids such as dexamethasone have shown promising therapeutic effects in conquering oral ulcers. Challenges this area are focused on enhancing the localized curative and responsive release. Herein, we presented a novel MXene-integrated hydrogel microneedle delivering to promote healing of ulceration. By loading MXene, microneedles enable NIR (Near Infrared)-responsive release inner for inflammation control tissue regeneration. In addition, MXene-induced local hyperthermia could inhibit bacteria, preventing possible infection ulcer lesions cavity. Based these features, demonstrated that our strategy relieve inflammation, reconstruction, accelerate wound rat models. Overall, NIR-responsive show significant promise promoting bring new ways disease treatment.
Язык: Английский
Процитировано
0
ACS Nano, Год журнала: 2024, Номер 18(42), С. 29223 - 29232
Опубликована: Окт. 11, 2024
Fibroblast growth factor receptor 1 (FGFR1) is emerging as a promising molecular target of lung cancer, and various FGFR1 inhibitors have exhibited significant therapeutic effects on cancer in preclinical research. Due to their low targeting ability or bioavailability, direct administration these may cause side effects. Herein, hydrogelator, Nap-Phe-Phe-Phe-Glu-Thr-Glu-Leu-Tyr-OH (
Язык: Английский
Процитировано
1