Lipid-Based Nanocarriers in Topical Applications for Skin Infections DOI

Monali M Upare,

Koustubh Mansing Thorawade,

Abhay Prakash Mishra

и другие.

Current Opinion in Pharmacology, Год журнала: 2025, Номер 83, С. 102541 - 102541

Опубликована: Май 16, 2025

Язык: Английский

Revolutionizing Prostate Cancer Therapy: Artificial intelligence – based Nanocarriers for Precision Diagnosis and Treatment DOI
Moein Shirzad,

Afsaneh Salahvarzi,

Sobia Razzaq

и другие.

Critical Reviews in Oncology/Hematology, Год журнала: 2025, Номер unknown, С. 104653 - 104653

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

5
A computer-aided, carrier-free drug delivery system with enhanced cytotoxicity and biocompatibility: a universal model for multifunctional lung cancer therapy DOI
Zhonglei Wang,

Wenjing Xu,

Shizeng Lei

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер 250, С. 114557 - 114557

Опубликована: Фев. 9, 2025

Язык: Английский

Процитировано

1
Smart nanomedicines powered by artificial intelligence: a breakthrough in lung cancer diagnosis and treatment DOI

Moloudosadat Alavinejad,

Moein Shirzad,

Mohammad Javad Javid-Naderi

и другие.

Medical Oncology, Год журнала: 2025, Номер 42(5)

Опубликована: Март 25, 2025

Язык: Английский

Процитировано

1
Dual Biopolymer Layer Using Nanoparticles with Active Substance Enclosed in Microcapsules: Innovative Solution for Slow Release of Ginkgo biloba L. Extract for Potential Therapies DOI Open Access
Przemysław Sitarek, Monika Owczarek, Tomasz Kowalczyk

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 3066 - 3066

Опубликована: Март 27, 2025

The dynamic development of various branches medicine and pharmacy, along with the emergence new preventive alternative therapies for diseases, creates opportunities solutions utilizing carriers active substances. Their therapeutic effect may occur through direct contact skin lesions or indirectly, where medicinal substances penetrate capillary network in deeper layers reach bloodstream. aim research was to obtain a matrix consisting two renewable-source polymers (chitosan ethylcellulose) core material derived from Ginkgo biloba green leaf extract (GBE). obtained ethylcellulose microcapsules encapsulated chitosan nanoparticles {Et[Ch(GB)NP]} were characterized respect size, shape, surface morphology (SEM microscopy), substance release kinetics (UV-VIS mathematical models). analyzed using UV-VIS spectroscopy models. released components assessed microbiologically activity against six bacterial strains fungal strains, as well chromatographically HPLC-ESI-QTOF-MS/MS fingerprinting. dual polymer layer exhibited slow material, which demonstrated microbiological activity. strongest antimicrobial effects observed Klebsiella pneumoniae Salmonella enteritidis, minimum inhibitory concentration (MIC) 410 µg/mL. double-layer structures more efficient physiological saline environment, best fit following zero-order model (regression coefficient R2 = 0.9939). show great potential applications medical industry. controlled properties antibacterial effectiveness make them promising carrier modern therapies.

Язык: Английский

Процитировано

0
Antioxidants in cancer therapy mitigating lipid peroxidation without compromising treatment through nanotechnology DOI Creative Commons
Daniel Ejim Uti, Item Justin Atangwho, Esther Ugo Alum

и другие.

Discover Nano, Год журнала: 2025, Номер 20(1)

Опубликована: Апрель 24, 2025

Cancer treatments often exploit oxidative stress to selectively kill tumour cells by disrupting their lipid peroxidation membranes and inhibiting antioxidant enzymes. However, plays a dual role in cancer progression, acting as both promoter suppressor. Balancing through therapy remains challenge, excessive activity may compromise the efficacy of chemotherapy radiotherapy. This review explores antioxidants mitigating while maintaining treatment efficacy. It highlights recent advancements nanotechnology-based targeted delivery optimize therapeutic outcomes. A comprehensive literature was conducted using reputable databases, including PubMed, Scopus, Web Science, ScienceDirect. The search focused on publications from past five years (2020-2025), supplemented relevant studies earlier years. Keywords such "antioxidants," "lipid peroxidation," "nanotechnology therapy," "oxidative stress" were utilized. Relevant articles critically analysed, graphical illustrations created. Emerging evidence suggests that nanoparticles, liposomes, polymeric metal-organic frameworks, others, can effectively encapsulate control release minimizing systemic toxicity. Stimuli-responsive carriers with tumour-specific targeting mechanisms further enhance delivery. Studies indicate these strategies help preserve normal cells, mitigate stress-related damage, improve challenges bioavailability, stability, potential interactions standard therapies remain. Integrating nanotechnology antioxidant-based interventions presents promising approach for optimizing therapy. Future research should focus refining modulation strategies, assessing profiles during treatment, employing biomarkers determine optimal dosing. balanced use adverse effects.

Язык: Английский

Процитировано

0
Lipid-Based Nanocarriers in Topical Applications for Skin Infections DOI

Monali M Upare,

Koustubh Mansing Thorawade,

Abhay Prakash Mishra

и другие.

Current Opinion in Pharmacology, Год журнала: 2025, Номер 83, С. 102541 - 102541

Опубликована: Май 16, 2025

Язык: Английский

Процитировано

0