Evodiamine alleviates DEHP-induced hepatocyte pyroptosis, necroptosis and immunosuppression in grass carp through ROS-regulated TLR4 / MyD88 / NF-κB pathway

Fish & Shellfish Immunology, Год журнала: 2023, Номер 140, С. 108995 - 108995

Опубликована: Авг. 11, 2023

Язык: Английский

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Sex, Nutrition, and NAFLD: Relevance of Environmental Pollution

Nutrients, Год журнала: 2023, Номер 15(10), С. 2335 - 2335

Опубликована: Май 16, 2023

Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic and represents an increasing public health issue given limited treatment options its association with several other metabolic inflammatory disorders. The epidemic, still growing prevalence NAFLD worldwide cannot be merely explained by changes in diet lifestyle that occurred last few decades, nor from their genetic epigenetic risk factors. It conceivable environmental pollutants, which act as endocrine disruptors, may contribute to spreading this pathology due ability enter food chain ingested through contaminated water. Given strict interplay between nutrients regulation hepatic metabolism reproductive functions females, pollutant-induced dysfunctions particular relevance for female liver, dampening sex differences prevalence. Dietary intake pollutants can particularly detrimental during gestation, when endocrine-disrupting chemicals interfere programming metabolism, accounting developmental origin offspring. This review summarizes cause-effect evidence increased incidence emphasizes need further studies field.

Язык: Английский

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Early clues and molecular mechanism involved in neurodegenerative diseases induced in immature mice by combined exposure to polypropylene microplastics and DEHP

Environmental Pollution, Год журнала: 2023, Номер 336, С. 122406 - 122406

Опубликована: Авг. 17, 2023

Язык: Английский

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Polystyrene microplastics with different sizes induce the apoptosis and necroptosis in liver through the PTEN/PI3K/AKT/autophagy axis

The Science of The Total Environment, Год журнала: 2023, Номер 899, С. 165461 - 165461

Опубликована: Июль 12, 2023

Язык: Английский

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Selenium deficiency exacerbates ROS/ER stress mediated pyroptosis and ferroptosis induced by bisphenol A in chickens thymus

Journal of Environmental Sciences, Год журнала: 2024, Номер 148, С. 13 - 26

Опубликована: Янв. 21, 2024

Язык: Английский

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Effects of microplastics on chemo-resistance and tumorigenesis of colorectal cancer

APOPTOSIS, Год журнала: 2025, Номер unknown

Опубликована: Фев. 9, 2025

Язык: Английский

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Short-term subacute di(2-ethylhexyl) phthalate exposure disrupts gut microbiota, metabolome, liver transcriptome, immunity, and induces liver injury in rats

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 292, С. 117948 - 117948

Опубликована: Фев. 26, 2025

Язык: Английский

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New insights into DEHP-induced inflammatory injury in chicken spleen: ROS/TLR4/MyD88 pathway and apoptosis/necroptosis-M1 polarization crosstalk

Poultry Science, Год журнала: 2025, Номер unknown, С. 105074 - 105074

Опубликована: Март 1, 2025

Язык: Английский

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CncC-Keap1-P450s pathway is involved in the detoxification of emamectin benzoate in the spongy moth Lymantria dispar

Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 199, С. 105765 - 105765

Опубликована: Янв. 2, 2024

Язык: Английский

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Fairy shrimp Branchinella kugenumaensis displays sensitivity to microplastic exposure

Journal of Oceanology and Limnology, Год журнала: 2024, Номер 42(4), С. 1186 - 1199

Опубликована: Март 27, 2024

Язык: Английский

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